得意(とくい)、上手(じょうず)、苦手(にがて)、下手(へた), etc.
得意 or 上手 carries the meaning of 'be good at/be skillful', whereas 苦手 or 下手 carries the meaning of 'be poor at/be unskillful'. These words belong to な-adjectives.
(NOTE: 上手 and 下手 concern purely 'skills/skillfullness', whereas 得意 and 苦手 may involve one's '(subjective) preference or favor', in addition to one's skill/skillfullness
These adjectives take -が to indicate at what one is good/bad, and
in this repsect, they are similar to 好き/きらい.
For instance, consider the following examples.