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Publications - 2003

Sasisekharan R, and Myette J (2003) The Sweet Science of Glycobiology American Scientist, September-October Issue

Sengupta S, Sellers LA, Cindrova T, Skepper J, Gherardi E, Sasisekharan R, and Fan TP. (2003) Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit hepatocyte growth factor/scatter factor-induced angiogenesis Cancer Res. 63: 8351-8359

Sengupta S, Sellers L, Lee RC, Gherardi E, Zhao G, Watson N, Sasisekharan R, and Fan TP (2003) Targeting of mitogen activated protein kinases and PI3 kinase inhibits HGF induced angiogenesis, Circulation 107 (23): 2955-2961.

Dull RO, Dinavahi R, Schwartz I, Humphries DE, Berry D, Sasisekharan R, and Garcia JG (2003) Lung endothelial heparan sulfates mediate cationic peptide-induced barrier dysfunction: a new role for the glycocalyx, Am J Physiol Lung Cell Mol Physiol 285(5):L986-95

Berry D, Shriver, Z, Natke B, Kwan CP, Venkataraman G, and Sasisekharan R (2003) Heparan sulfate glycosaminoglycans derived from endothelial cells and smooth muscle cells differentially modulate Fibroblast Growth Factor-2 biological activity through Fibroblast Growth Factor Receptor-1, Biochem J, 373:241-9.

Myette J, Shriver Z, Claycamp C, McLean M, Venkataraman G, and Sasisekharan R (2003) The heparin/heparan sulfate 2-O-sulfatase fro m Flavobacterium heparinum: molecular cloning, recombinant expression, and biochemical characterization. J Biol Chem, 278, 12157-66.

Raman R, Myette J, Shriver Z, Pojasek K, Venkataraman G, and Sasisekharan R (2003) The heparin/heparan sulfate 2-O-sulfatase from flavobacterium heparinum: a structural and biochemical study of the enzyme active site and saccharide substrate specificity. J Biol Chem, 278, 12167-74.

Raman R, Venkataraman G, Ernst S, Sasisekharan V, and Sasisekharan R (2003) Structural specificity of heparin binding in FGF family of proteins. Proc Natl Acad Sci U S A, 100, 2357-62.

Sundaram M, Qi Y, Shriver Z, Liu D, Zhao G, Venkataraman G, Langer R, and Sasisekharan R (2003) Rational design of low molecular weight heparins with improved in vivo activity. Proc Natl Acad Sci U S A, 100, 651-6.

Sengupta S, Gherardi E, Sellers LA, Wood JM, Sasisekharan R, and Fan TP (2003) Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor. Arterioscler Thromb Vasc Biol, 23, 69-75

Last Updated: August 29, 2005