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Publications - 2009

Hensley SE, Suman RD, Bailey AL, Schmidt LM, Hickman HD, Jayaraman A, Viswanathan K, Raman R, Sasisekharan R, Bennick JR, and Yewdell JW. Hemagluttinin Receptor Binding Avidity Drives Influenza A Virus Antigenic Drift. Science [In Press]

Guerrini M, Shriver Z, Bisio A, Naggi A, Casu B, Sasisekharan R, Torri G. The tainted heparin story: an update. Thromb Haemost. 2009 Nov;102(5):907-11.

Kishimoto TK, Qi YW, Long A, Capila I, Sasisekharan R, Guerrero L, Fier I, Roach J, Venkataraman G. M118 - A rationally engineered low-molecular-weight heparin designed specifically for the treatment of acute coronary syndromes. Thromb Haemost. 2009 Nov;102(5):900-6.

Bisio A, Vecchietti D, Citterio L, Guerrini M, Raman R, Bertini S, Eisele G, Naggi A, Sasisekharan R, Torri G. Structural features of low-molecular-weight heparins affecting their affinity to antithrombin. Thromb Haemost. 2009 Nov;102(5):865-73.

Sasisekharan R, Shriver Z. From crisis to opportunity: A perspective on the heparin crisis. Thromb Haemost. 2009 Nov;102(5):854-8.

Harfouche R, Hentschel DM, Piecewicz S, Basu S, Print C, Eavarone D, Kiziltepe T, Sasisekharan R, Sengupta S. Glycome and Transcriptome Regulation of Vasculogenesis. Circulation 2009 Oct 26 [Epub ahead of print]

Guerrini M, Zhang Z, Shriver Z, Naggi A, Masuko S, Langer R, Casu B, Linhardt RJ, Torri G, Sasisekharan R. Orthogonal analytical approaches to detect potential contaminants in heparin. Proc Natl Acad Sci U S A 2009 Oct 6; 106(40):16956-61.

Myette JR, Soundararajan V, Behr J, Shriver Z, Raman R, Sasisekharan R. The heparin/heparan sulfate N-sulfamidase from Flvobacterium heparinum : Structuaral and biochemical investigation of catalytic Nitrogen-Sulfur bond cleavage. J Biol Chem 2009 Sep 2 [Epub ahead of print]

Myette JR, Soundararajan V, Shriver Z, Raman R, Sasisekharan R. The heparin/heparan sulfate 6-O-sulfatase from Flavobacterium heparinum : Integrated Structural and biochemical investigation of enzyme active site and substrate specificity. J Biol Chem 2009 Sep 2 [Epub ahead of print]

Shriver Z, Raman R, Viswanathan K, Sasisekharan R. Context-specific target definition in influenza a virus hemagglutinin-glycan receptor interactions. Chem Biol 2009 Aug 28;16(8):803-14.

Maines TR, Jayaraman A, Belser JA, Wadford DA, Pappas C, Zeng H, Gustin KM, Pearce MB, Viswanathan K, Shriver ZH, Raman R, Cox NJ, Sasisekharan R, Katz JM, Tumpey TM. Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice. Science 2009 Jul 24; 325(5939):484-7.

Soundararajan V, Tharakaraman K, Raman R, Raguram S, Shriver Z, Sasisekharan V, Sasisekharan R. Extrapolating from sequence--the 2009 H1N1 'swine' influenza virus. Nat Biotechnol 2009 Jun; 27(6):510-3

Bulmer MS, Bachelet I, Raman R, Rosengaus RB, and Sasisekharan R. Targeting an antimicrobial effector function in insect immunity as a pest control strategy. Proc Natl Acad Sci USA. 2009 Aug 4; 106(31):12652-7

Prabhakar V, Capila I, and Sasisekharan R The structural elucidation of glycosaminoglycans. Methods Mol Biol 2009; 534:147-56

Prabhakar V, Capila I, and Sasisekharan R Glycosaminoglycan characterization methodologies: probing biomolecular interactions. Methods Mol Biol 2009; 534:331-40

Van Hoeven N, Pappas C, Belser JA, Maines TR, Zeng H, Garcia-Sastre A, Sasisekharan R, Katz JM, and Tumpey TM. Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air. Proc Natl Acad Sci USA. 2009 Mar 3; 106(9):3366-71

Prabhakar V, Capila I, Soundararajan V, Raman R, and Sasisekharan R. Recombinant expression, purification, and biochemical characterization of chondroitinase ABC II from proteus vulgaris. J Biol Chem 2009 Jan 9;284(2):974-82.

Last Updated: November 6, 2009