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Biotechnology Process Engineering Center (BPEC)

The Biotechnology Process Engineering Center (BPEC) is an interdisciplinary research center under the Biological Engineering Division at the Massachusetts Institute of Technology (MIT). BPEC was founded in 1985 as one of the first national Engineering Research Centers (ERCs) funded by the National Science Foundation (NSF) and has evolved to a current core mission of fusing the practice of engineering with the science of biology to meet technological challenges in the biotechnology industry. The underlying premise of this mission is that the molecular and genomics revolutions in biology require engineering analysis, design, and synthesis in order that breakthrough discoveries can be translated effectively into products and create new industries – as well as to foster further developments in basic science.

The BPEC focuses on 2 specific problems in the areas of therapeutic gene and stem cell technologies: (a) gene delivery to stem cells that form blood, in order to correct inborn genetic problems; and (b) gene delivery to cells in liver to treat liver cancer. The results of BPEC research activities also provide a foundation for treating other degenerative diseases (like diabetes), the repair of injured tissues (e.g., spinal cord), and therapies for other types of cancers – and also to preventative DNA vaccines that can arrest the onset of disease altogether. BPEC research activities thus encompass problems important in the western world but -- like liver cancer – are also highly endemic in developing countries. The problems addressed provide a unifying thread among the diverse, active labs of the BPEC investigators, each of whom brings perspective from an array of other basic science and engineering projects funded by NIH, other NSF divisions, DOD, industry, and foundations.

The Faculty

Prof. Linda G. Griffth, Director
MIT Biological Engineering Division; MIT Department of Mechanical Engineering

Prof. Douglas Lauffenburger, Executive Director of Development
MIT Biological Engineering Division; MIT Department of Chemical Engineering; MIT Department of Biology; Center for Biomedical Engineering; Center for Cancer Research

MIT Biological Engineering Division; MIT Department of Chemical Engineering; MIT Department of Biology; Center for Biomedical Engineering; Center for Cancer Research



Prof. Harvey F. Lodish,
Executive Director of Research
MIT Department of Biology; MIT Biological Engineering Division; Whitehead Institute

Prof. Alexander M. Klibanov
MIT Department of Chemistry; MIT Biological Engineering Division

Prof. Robert S. Langer
MIT Department of Chemical Engineering; MIT Biological Engineering Division; MIT/HMS Division of Health Sciences & Technology

Prof. Leona D. Samson
Center for Environmental Health Sciences; MIT Biological Engineering Division

Prof. Forrest White
Assistant Professor of Biological Engineering
 

Prof. K. Dane Wittrup
MIT Department of Chemical Engineering

 
 
MIT
Massachuesetts Institute of Technology


77 Massachusetts Avenue, Bldg. 7-104, Cambridge, MA 02139
Tel: 617-253-7306, Fax: 617-258-8816

UROP Contacts

UROP Coordinator:

Mr. Dan Darling
16-429, x3-0805
ddarling@mit.edu

Department Head:

Prof. Linda G. Griffith
16-429, x3-0805
griff@mit.edu

UROP Payroll:

Mr. Dan Darling
16-429, x3-0805
ddarling@mit.edu

UROP for Credit:

Arranged through the faculty supervisor's academic department.

Some Related Areas for UROPs:

Biological Engineering, Biology, Chemical Engineering, Chemistry and Computational and Systems Biology.