Final Project
Format of Final Report
Paper Assignments
- Nature Cell Biology 9, 724 - 728 (2007)
Irreversible cell-cycle transitions are due to systems-level feedback
Bela Novak, John J. Tyson, Bela Gyorffy and Attila Csikasz-NagyJames Kraemer and Russell Spitzer
- Nature 403: 6767(2000)
A synthetic oscillatory network of transcriptional regulators
Elowitiz and LeiblerAnthony Shiver and Geoffrey Rollins
- PLoS Computational Biology (2008)
Spatial Bistability Generates hunchback Expression Sharpness in the Drosophila Embryo
Lopes, Vieira, Holloway, Bisch and SpirovHenry Lin and Edwin Rodriguez
- PLoS Computational Biology 2: e59 (2006)
Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System
Hiroyuki Kurata, Hana El-Samad, Rei Iwasaki, Hisao Ohtake, John C. Doyle, Irina Grigorova, Carol A. Gross, Mustafa KhammashEmmanuel Yera and Ryan Gile
- Nature, 427:737
Multistability in the lactose utilization network of Escherichia coli
Ozbudak, Thattai, Lim, Shralman and van OudenaarGenevieve Erwin and Christopher Fuller
- Cell. 2005 Aug 26;122(4):565-78
Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations
Pomerening JR, Kim SY, Ferrell JE Jr.Joanna Lipinski and Roxana Ordonez
- Current Biology, 18: R244 (2008)
Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses
FerrellDan Lu and Rocco Varela
- PNAS, 88:9107-9111
A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase
A GoldbeterAaron Daub and Jason Park