5.310 is a 12 unit class (2-8-2) which introduces experimental chemistry for students who are not majoring in Course V. See the Registrar's listing for the other administrative information. The course covers principles and applications of chemical laboratory techniques, including preparation and analysis of chemical materials, measurement of pH, gas and liquid chromatography, visible-ultraviolet spectrophotometry, infrared spectroscopy, kinetics, data analysis, and elementary synthesis. Enrollment is limited. Students gain experience by completing the five experiments detailed below.
In this experiment, the student is given an "unknown" amino acid and asked to identify it using several procedures. This introduces several basic manipulative techniques of preparative chemistry and quantitative volumetric analysis including preparation and characterization of a derivative, recrystallization, determination of equivalent weight by using titration and determination of melting points.
This experiment involves the separation and characterization of the major components found in either caraway oil or spearmint oil. These two oils each contain limonene and carvone, but each oil contains a different isomer of these chiral compounds. During the course of the experiment, the student will be exposed to fractional distillation under vacuum, gas chromatography, refractometry, polarimetry, and IR absorption spectroscopy.
In this experiment, the student is given a mixture of a strong monoprotic acid and a weak polyprotic acid. A standardized base solution is prepared and then potentiometric titrations are performed. The resulting data are used to determine the molar concentrations of the two acids and the second pKa value for the polyprotic acid.
This is an integrated experiment comprising topics from inorganic, organic, analytical, physical, and computational chemistry. It introduces the student to some of the basics of acquiring kinetic data, manipulating the data to extract information such as reaction order and rate constants, and how to assess the catalytic effect of the reaction environment upon rate constants.