8.592 - HST.452J (Spring 2022)

Statistical Physics in Biology

Lecture 10

(zoom link: https://mit.zoom.us/j/93992933747)

Recording of the zoom session

Physical forces relevant to biology

1. Amino Acids:
• Structure: backbone, residues, bending, ...
• Characteristics: size, charge, ...
2. Forces:
• van der Waals attraction & Lenard-Jones potential
• Hydrogen bonds
• Hydrophobic forces
3. Protein structure
   • secondary
   • 3D structure
4. Sequence-structure mapping
   • analogous and homologous proteins
   • hydrophobic core
   • periodicity
                                                                                            (Slides)