8.592 - HST.452J (Spring 2022)
Statistical Physics in Biology
Lecture 6
(No recordings for Friday lectures)
Evolving Populations (backward Kolmogorov)
The backward Kolmogorov equation:
Steady states with absorbing states
Derivation of the backward Kolmogorov equation
Fixation:
General solution of the backward Kolmogorov equation
Fixation probability with selection
Fixation probability of a new mutation
Mean first passage times:
Mean time to fixation
Mean time to loss
Mean survival time
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Lecture Notes
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8.592
lec6- last update 2/10/2022 by M. Kardar