Selected Publications


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Orgueira, H.A.; Bartolozzi, A.; Schell, P.H.; Litjens, R.; Palmacci, E.R.; Seeberger, P.H.; Modular Synthesis of Heparin Oligosaccharides Chem. Eur. J. 2002, in press.
Bosse, F.; Marcaurelle, L.A.; Seeberger, P.H.; Linear Synthesis of the Tumor-Associated Carbohydrate Antigens Globo-H, SSEA-3 and Gb3; J. Org. Chem. 2002, 66, in press.
Herzner, H.; Palmacci, E.R.; Seeberger, P.H.; A Short Total Synthesis of 8,10-O-Methylbergenin; Organic Letters 2002, 4, in press.
Schofield, L.; Hewitt, M.C.; Evans, K.; Siomos, M.A.; Seeberger, P.H.; Synthetic Glycosylphosphatidylinositol of Malaria as a Candidate Anti-toxic Vaccine; Nature, 2002, in press.
Hunt, D.K.; Seeberger, P.H.; Linker Influence on the Stereochemical Outcome of Glycosylations Utilizing Solid Support-bound Glycosyl Phosphates; Organic Letters 2002, 4, 2751-2754.
Orgueira, H.A.; Bartolozzi, A.; Schell, P.H.; Seeberger, P.H.; Stereocontrol of Glycosylation Reactions by Conformational Locking of the Glycosyl Acceptor in Disaccharide Formation; Angew. Chem. Int. Ed. 2002, 41, 2128-2131.
Ratner, D.M.; Plante, O.J.; Seeberger, P.H.; A Linear Synthesis of Branched High-Mannose Oligosaccharides from the HIV-1 Viral Surface Envelope Glycoprotein gp120; Eur. J. Org. Chem. 2002, 826-833.

Love, K.R.; Andrade, R.B.; Seeberger, P.H.; Linear Synthesis of a Protected H-type II Pentasaccharide Using Glycosyl Phosphate Building Blocks; J. Org. Chem. 2001, 66, 8165-8176.

Palmacci, E.R.; Hewitt, M.C.; Seeberger P.H.; 'Cap-Tag' - Novel Methods for the Rapid Purification of Oligosaccharides Prepared by Automated Solid-Phase Synthesis; Angew. Chem. Int. Ed. 2001, 40, 4433-4437.
Hewitt, M.C.; Seeberger P.H.; Automated Solid-Phase Synthesis of the Leishmania Cap
Tetrasaccharide; Organic Letters 2001, 3, 3699-3702.
Plante, O.J.; Palmacci, E.R.; Andrade, R.B.; Seeberger, P.H.
Oligosaccharide Synthesis Using Glycosyl Phosphate and Dithiophosphate Triesters as Glycosylating Agents., J. Am. Chem. Soc. 2001, 123, 9545-9554.

Yabe, T.; Shukla, D.; Spears, P.; Rosenberg, R.D.; Seeberger, P.H.; Shworak, N.W.A Portable Sulfotransferase Domain Determines Sequence Specificity of Heparan Sulfate 3-O-Sulfotransferases., Biochem. J. 2001, 359, 235-241.

Hewitt, M.C.; Seeberger, P.H. Solution and Solid Support Synthesis of a Potential Leishmaniasis Carbohydrate Vaccine., J. Org. Chem. 2001, 66, 4233-4243.

Plante, O.J.; Palmacci, E.R.; Seeberger, P.H. Automated Solid-Phase Synthesis of Oligosaccharides, Science 2001, 291, 1523-1527.
[ Abstract ] [ full text ]

Seeberger, P.H.; Haase, W.-C. Solid-Phase Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries., Chem. Rev. 2000, 100, 4349-4394.


Plante, O.J.; Buchwald, S.L.; Seeberger, P.H. Halobenzyl Ethers as Protecting Groups for Organic Synthesis., J. Am. Chem. Soc. 2000, 122, 7148-7149.

Plante, O.J.; Andrade, R.B.; Seeberger, P.H. Synthesis and Use of Glycosyl Phosphates as Glycosylating Agents., Org. Lett. 1999, 1, 211-214.

Seeberger, P.H.; Eckhardt, M.; Gutteridge, C.A.; Danishefsky, S.J. Coupling of Glycal Derived Thioethyl Glycosyl Donors with Glycal Acceptors. An Advance in the Scope of the Glycal Assembly., J. Am. Chem. Soc. 1997, 119, 10064-10072.

Seeberger, P.H.; Beebe, X.; Sukenick, G.D.; Pochapsky, S.; Danishefsky, S.J. Monitoring the Progress of Solid-Phase Oligosaccharide Synthesis by High-Resolution Magic Angle Spinning NMR: Observation of Enhanced Selectivity for beta-Glycoside Formation from alpha-1,2-Anhydrosugar Donors in Solid Phase Couplings., Angew. Chem. 1997, 109, 507-509 and Angew. Chem. Int. Ed. 1997, 36, 491-493.

Seeberger, P.H.; Jorgensen, P.N.; Bankaitis-Davis, D.; Beaton, G.; Caruthers, M.H. 5'-Dithiophosphoryl Deoxyoligonucleotides: Synthesis and Biological Studies., J. Am. Chem. Soc. 1996, 118, 9562-9566.

Seeberger, P.H.; Yau, E.; Caruthers, M.H. 2'-Deoxynucleoside-dithiophosphates: Synthesis and Biological Studies., J. Am. Chem. Soc. 1995, 117, 1472-1478.

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