MIT IAP

IAP 2002 Activity


Cutting-edge Technologies for Biomedical Research: Bioinformatics and Microarrays
Prof. Ilaria Rebay
No enrollment limit, no advance sign up
Participants welcome at individual sessions (series)
Prereq: none

This series will discuss cutting edge genomic-based technologies that are currently revolutionizing every aspect of biological research. There will be presentations on the latest advances in microarray technologies, including DNA, protein, and cell-based assay systems, as well as discussions of the bioinformatics being developed to analyze the vast amounts of information generated by these approaches.
Contact: Prof. Ilaria Rebay, WI 501B, x8-6399, rebay@wi.mit.edu
Sponsor: Biology

Cell and Drug Microarrays: New Tools to Study Gene Function in Mammalian Cells
David Sabatini, M.D., Ph.D, Whitehead Institute
Discussion of innovative genomic approaches using cell-based microarray technology.
Tue Jan 15, 12-01:30pm, WI Auditorium

Chemical Genetic Screens in Mammalian Cells
Brent Stockwell, Ph.D., Whitehead Institute
Discussion of the use of small molecule screening to identify chemical compounds that can be used to alter a protein in ways that illuminate the functionality of individual genes and the proteins they produce. In the future, this exciting technology will be used to develop new therapies for the treatment of human disease.
Thu Jan 17, 12-01:30pm, WI Auditorium

Bioinformatics of RNA Splicing
Chris Burge, Ph.D., MIT
One of the major challenges after obtaining the complete genomic sequence of an organism, whether it be a fungus or a primate, is to annotate the sequence so as to accurately identify all of the predicted gene products. Discussion of novel computational approaches to studying RNA splicing specificity and improved methods for identifying genes in eukaryotic genomes.
Tue Jan 22, 12-01:30pm, WI Auditorium

The Path Not Taken: How to Recognize Signaling Pathways in Global Protein Networks
Trey Ideker, Ph.D., Whitehead Institute
Discussion of new computational tools for building models of molecular interactions that are predictive of gene expression.
Thu Jan 24, 12-01:30pm, WI Auditorium

Hunting for Disease Genes in the Post-genomic World
Mark Daly, Whitehead Institute
Discussion of the use of genomic information in understanding how patterns of genetic variation can be used to predict disease susceptibility in human populations.
Mon Jan 28, 12-01:30pm, 68-181

Using Microarrays to Study Protein Function
Gavin MacBeath, Ph.D., Harvard University
Discussion of how small molecule, protein, and antibody based microarray technology can be used to understand protein regulation on a genomic scale.
Tue Jan 29, 12-01:30pm, 68-181
Latest update: 16-Nov-2001


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