Klavs F Jensen, Professor Chemical Engineering
Enrollment: Send CV, candidate interview
Sign-up by 01/01
Limited to 3 participants
Attendance: Participants must attend all sessions
The Pharmacy on Demand initiative seeks to create mobile, reconfigurable platforms capable of synthesizing multiple active pharmaceutical ingredients. Following on from past iterations, the group is now working towards the design build and implementation of this platform for one selected API and gaining regulatory approval of the synthesis and platform. To accomplish this, the system and synthesis needs to be characterized to ensure a complete understanding of the different process parameters, residence time distributions (RTD) etc.
UROPs will be involved with the characterization of different system components, i.e. reactors, liquid/liquid separators, pumps etc. Accurate RTD measurements will be acquired for each of the components and integrated into a basic software model that can predict RTD of the entire system; an essential criterion if the project goal of regulatory approval is to be realized. Students will also get some exposure to organic flow synthesis, the creation and use of FTIR models as a process monitoring tool and some basic HPLC exposure.
Prerequisites (if any): The major requirements are motivation and an eye for detail. Knowledge of (or interest in) the Pharmaceutical industry, basic organic chemistry, reactor characterization/RTD models and some experience with LabVIEW/Matlab.
Contact: Luke Rogers, 66-5.07, 857 559-3226, LROGERS@MIT.EDU