Install on build machine: libxslt1-dev elinks Download extra Perl modules HTML::Template, XML::Simple with: cpan -i HTML::Template cpan -i XML::Simple (these will also be needed at runtime and need to also be installed in locker). To verify which are installed, run instmodsh. Using meme_4.11.4.tar.gz, run: ./configure --prefix=/mit/meme_v4.11.4 --with-url=http://meme-suite.org make make test make install Download HTML-Template-2.97.tar.gz, XML-Simple-2.24.tar.gz with: cpan -g HTML::Template cpan -g XML::Simple unpack in temp location and install with: perl Makefile.PL PREFIX=/mit/meme_v4.11.4 make make test make install Look in /mit/meme_v4.11.4/bin, grepping for HTML::Template and XML::Simple to see which scripts use these. For each that does (currently meme-chip, nmica2meme, also lib/perl/MemeWebUtils.pm) add line near top: use lib qw(/mit/meme_v4.11.4/share/perl/5.18.2); Separate architecture installs with @sys links; launch with .attachrc* scripts that put /mit/meme_v4.11.4/bin on path and create "${HOME}/.meme/LOGS" if it doesn't exist already.