R: Model function for the Phenobarb data

phenoModel {nlme}

R Documentation

Model function for the Phenobarb data

A model function for a model used with the Phenobarb data. This function uses compiled C code to improve execution speed.

phenoModel(Subject, time, dose, lCl, lV)

`Subject`	an integer vector of subject identifiers. These should be sorted in increasing order.
`time`	numeric. A vector of the times at which the sample was drawn or the drug administered (hr).
`dose`	numeric. A vector of doses of drug administered (μg/kg).
`lCl`	numeric. A vector of values of the natural log of the clearance parameter according to `Subject` and `time`.
`lV`	numeric. A vector of values of the natural log of the effective volume of distribution according to `Subject` and `time`.

See the details section of Phenobarb for a description of the model function that phenoModel evaluates.

a numeric vector of predicted phenobarbital concentrations.

José Pinheiro and Douglas Bates bates@stat.wisc.edu

Pinheiro, J. C. and Bates, D. M. (2000) Mixed-effects Models in S and S-PLUS, Springer. (section 6.4)

[Package nlme version 3.1-131 Index]