Virtual Matrices:											Pocket 1
																										Pocket #							1	2
																						Allele	Allele	Allele	Allele	1	4	6	7	9		A	-5.00	-5.00
																									B1*0101	1	1	1	1	1		C	-5.00	-5.00		Virtual Matrices are from J. Hammer in the
																									B1*1502	1	2	2	2	1		D	-5.00	-5.00		paper by T. Sturniolo, et al., Nat. Biotech.,
																									B1*0305	1	3	3	3	3		E	-5.00	-5.00		June, 1999, 17:555-61
																									B1*0309	1	3	3	3	2		F	0.00	-1.00
																									B1*0421	1	4	4	4	2		G	-5.00	-5.00
																								B1*0426	B1*0401	1	4	4	4	3		H	-5.00	-5.00
																									B1*0405	1	6	4	6	5		I	-1.00	0.00
Matrices																									B1*0408	1	6	4	6	3		K	-5.00	-5.00
																									B1*1101	1	7	3	7	3		L	-1.00	0.00
Hammer, DR1 (additive)											Sette, DR1 (multiplicative)													B1*1305	B1*1128	1	7	3	7	2		M	-1.00	0.00
	1	2	3	4	5	6	7	8	9			1	2	3	4	5	6	7	8	9					B1*1307	1	7	3	9	3		N	-5.00	-5.00
A	-5	0	0	0	0	0	0	0	0		A	0	1.93	3.51	4.14	1.59	2.42	1.89	1.25	4.09					B1*1321	1	7	3	7	5		P	-5.00	-5.00
C	0	0	0	0	0	0	0	0	0		C	0	0.22	0.15	0.49	0.06	0.14	0.31	0.45	0.35				B1*0703	B1*0701	1	8	5	8	4		Q	-5.00	-5.00
D	-5	-1.3	-1.3	-2.4	0	-2.7	-2	0	-1.9		D	0	0.85	0.31	0.2	0.21	0	0.11	0.08	0.39					B1*0801	1	9	3	9	5		R	-5.00	-5.00
E	-5	0.1	-1.2	-0.4	0	-2.4	-0.6	0	-1.9		E	0	0.31	0.47	0.59	0.57	0	0.16	0.53	0.27					B1*0802	1	9	3	9	3		S	-5.00	-5.00
F	0	0.8	0.8	0.08	0	-2.1	0.3	0	-0.4		F	1.51	2.05	0.49	0.22	0.4	0	0.91	0.89	0.79					B1*0813	1	9	3	6	3		T	-5.00	-5.00
G	-5	0.5	0.2	-0.7	0	-0.3	-1.1	0	-0.8		G	0	1.29	3.38	2.13	1.73	0	0.23	1.58	0.44					B1*0817	1	9	3	7	5		V	-1.00	0.00
H	-5	0.8	0.2	-0.7	0	-2.2	0.1	0	-1.1		H	0	0.51	0.11	0.68	1.57	0	1.81	1.2	0.55				B5*0105	B5*0101	1	10	6	10	6		W	0.00	-1.00
I	-1	1.1	1.5	0.5	0	-1.9	0.6	0	0.7		I	1	3.84	1.59	1.1	1.3	0.75	3.47	0.67	1.32				B1*1323	B1*1114	1	11	3	11	3		Y	0.00	-1.00
K	-5	1.1	0	-2.1	0	-2	-0.2	0	-1.7		K	0	2.69	2.32	0.49	0.67	0	1.33	2.24	0.44				B1*1302	B1*1120	1	11	3	11	2
L	-1	1	1	0.9	0	-2	0.3	0	0.5		L	0.97	1.2	0.64	3.08	2.32	0.85	2.02	3.1	0.83					B1*0102	2	1	1	1	1			Pocket 4
M	-1	1.1	1.4	0.8	0	-1.8	0.09	0	0.08		M	2.82	1.07	2.62	7.66	0.93	2.67	7.27	1.01	4.39				B1*1506	B1*1501	2	2	2	2	1			1	2	3	4	5	6	7	8	9	10	11
N	-5	0.8	0.5	0.04	0	-1.1	0.1	0	-1.2		N	0	0.63	1.41	1.2	0.75	0	1.16	0.43	1.15					B1*0301	2	3	3	3	2		A	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
P	-5	-0.5	0.3	-1.9	0	-0.2	0.07	0	-1.1		P	0	0.43	0.88	5.42	2.57	0.63	1.78	1.63	1.52		B1*0311	B1*0307	B1*0308	B1*0306	2	3	3	4	3		C	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Q	-5	1.2	0	0.1	0	-1.8	0.2	0	-1.6		Q	0	1.38	1.27	7.07	1.58	0	1.06	3.65	1.54					B1*1107	2	3	3	3	3		D	-2.40	-0.40	2.30	1.40	-2.30	-1.10	-1.70	-1.60	-1.00	-1.90	-1.40
R	-5	2.2	0.7	-2.1	0	-1.8	0.09	0	-1		R	0	0.8	0.49	0.43	0.37	0	1.08	1.43	0.83					B1*0402	2	5	4	5	3		E	-0.40	-0.60	-1.00	1.50	-2.30	-1.10	-1.70	-1.40	-1.00	-1.30	-1.10
S	-5	-0.3	0.2	-0.7	0	-0.6	-0.2	0	-0.3		S	0	0.87	0.48	0.32	0.58	0.74	1.03	1.25	1.03				B1*0423	B1*0404	2	6	4	6	3		F	0.08	2.40	-1.00	-0.90	0.30	1.00	0.40	0.20	0.50	-0.60	0.80
T	-5	0	0	-1	0	-1.2	0.09	0	-0.2		T	0	0.57	2.08	0.3	1.59	1.26	1.51	1.73	2.32					B1*0410	2	6	4	6	5		G	-0.70	0.00	0.50	-1.60	-0.70	-2.40	-1.70	-1.10	-1.00	-1.60	-1.50
V	-1	2.1	0.5	-0.1	0	-1.1	0.7	0	0.3		V	0.74	2.95	1.08	0.79	1.97	1.16	2.89	0.57	5.89			B1*1106	B1*1311	B1*1104	2	7	3	7	3		H	-0.70	1.10	0.00	1.10	1.20	-1.00	-0.60	0.10	-1.00	-1.40	1.50
W	0	-0.1	0	-1.8	0	-2.4	-0.1	0	-1.4		W	0.3	0.63	0.69	0.56	0.14	0	0.61	0.35	0.58					B1*0804	2	9	3	9	3		I	0.50	0.60	0.50	0.80	0.08	1.10	0.90	1.10	0.30	1.30	-0.60
Y	0	0.9	0.8	-1.1	0	-2	0.5	0	-0.9		Y	0.88	0.51	1.22	0.36	2.04	0	0.99	0.26	0.42					B1*0806	2	9	3	9	5		K	-2.10	-0.70	-1.00	-1.70	0.10	-1.50	-0.50	-1.30	2.30	-1.70	0.80
	DR4 plus Virtual Matrix (Nat Biotech 17:555)											Southwood, et al., JI '98, 160:3363-73											B1*1121	B1*1322	B1*1102	2	11	3	11	3		L	0.90	0.50	0.00	0.80	-0.60	1.00	1.10	-0.80	0.70	0.60	0.40
Hammer, DR4 (additive)											Sette, DR4 (multiplicative)												B1*1327	B1*1328	B1*1301	2	11	3	11	2		M	0.80	1.00	0.00	0.90	0.60	1.80	1.00	-0.40	1.40	1.70	0.80
	1	2	3	4	5	6	7	8	9			1	2	3	4	5	6	7	8	9					B1*1304	2	11	3	11	5		N	0.04	-0.20	0.20	0.90	-0.40	-0.70	0.00	-1.10	0.00	-1.70	0.10
A	-5	0	0	0	0	0	0	0	0		A	0	0.96	1.04	1.57	0.59	0.65	0.86	0.82	1.62												P	-1.90	-0.30	-1.00	-1.60	-1.30	-1.30	-1.70	-1.20	-1.00	-1.50	-1.50
C	0	0	0	0	0	0	0	0	0		C	0	0.57	0.74	1.12	0.83	0.47	0.94	0.28	1.1												Q	0.10	-0.80	0.00	0.80	-0.40	0.00	-0.40	-1.50	-1.00	-0.70	0.60
D	-5	-1.3	-1.3	1.7	-0.2	0	-1.1	-1.1	-2.6		D	0	0.34	0.33	1.4	0.4	0	0.58	0.53	0.24												R	-2.10	0.20	-1.00	-1.90	1.00	-2.40	-0.70	-1.10	2.30	-1.70	0.20
E	-5	0.1	-1.2	0.8	-0.1	-1.2	-0.2	-0.2	-1.8		E	0	0.31	1.09	0.42	0.42	0	0.29	0.61	0.25												S	-0.70	-0.30	0.70	0.80	-1.00	-0.70	-0.70	1.50	-1.00	-0.50	-0.60
F	0	0.8	0.8	-0.8	0.3	-1.3	-0.8	0.1	-0.8		F	2.33	3.66	1.85	0.8	1.58	0	1.84	1.34	1.12												T	-1.00	-0.30	-1.00	0.70	-0.50	-0.90	-0.60	1.40	-1.00	0.30	-1.10
G	-5	0.5	0.2	-1.5	-0.2	-1.1	-1.5	-0.5	-0.2		G	0	1.14	0.64	0.43	0.48	0	0.49	1.19	0.52												V	-0.05	0.20	0.00	-0.90	-0.70	0.50	0.40	0.90	0.30	1.10	-0.90
H	-5	0.8	0.2	0.8	-0.1	-1.6	-0.8	0	0.3		H	0	0.78	0.15	1.14	0.93	0	13.8	1.4	5.15												W	-1.80	0.40	-1.00	-1.20	1.60	-0.05	-0.10	-1.10	0.00	-1.40	0.70
I	-1	1.1	1.5	0.8	0.1	-0.2	-0.2	-0.1	-0.4		I	0.79	1.74	1.01	1.91	4.39	0.98	2.36	1.66	2.75												Y	-1.10	2.50	-1.00	-1.60	-0.40	-0.40	-0.70	-0.90	2.20	-0.60	0.40
K	-5	1.1	0	-2.2	0.3	-2.3	-1.2	0.9	-0.9		K	0	1.44	1.25	0.53	0.4	0	0.62	0.64	0.55
L	-1	1	1	-0.6	0.1	-1.3	0.4	0.6	-1.3		L	0.81	0.86	1.88	1.28	1.11	0.67	1.36	1.08	0.83													Pocket 6
M	-1	1.1	1.4	1.4	0.3	-1.3	0.7	0.4	-0.4		M	1.14	12.8	1.49	2.77	0.32	0.74	8.11	1.98	4.05													1	2	3	4	5	6
N	-5	0.8	0.5	0.5	0.2	1.7	-0.1	0.7	-1.1		N	0	0.44	1.72	1.42	1.89	0	0.84	0.43	1.64												A	0.00	0.00	0.00	0.00	0.00	0.00
P	-5	-0.5	0.3	-2.1	0.5	0.1	-0.3	-0.2	-1.6		P	0	0.56	0.31	1.44	2.46	0.86	2.83	2.12	2.18												C	0.00	0.00	0.00	0.00	0.00	0.00
Q	-5	1.2	0	1.1	0.1	-1.2	-0.5	1.6	0.7		Q	0	0.4	0.38	1.61	2.09	0	0.31	0.71	0.62												D	-2.70	-0.40	-2.40	-1.10	-2.50	-2.00
R	-5	2.2	0.7	-1.5	0	-2.2	-1.2	0.7	-0.9		R	0	1.09	0.5	0.69	0.39	0	0.14	0.41	1.22												E	-2.40	-1.00	-1.40	-2.40	-2.50	-2.00
S	-5	-0.3	0.2	1.1	0.4	1.7	-0.4	0.6	1.2		S	0	1.55	1.31	1.29	1.76	1.11	1.23	2.93	1.54												F	-2.10	-0.30	-1.40	-1.10	-0.80	-1.70
T	-5	0	0	0.8	0.6	1.9	-0.2	0.5	-0.3		T	0	1	4.34	0.89	1.32	1.86	3.07	1.76	1.64												G	-0.30	0.50	-0.70	-1.50	-0.60	-0.30
V	-1	2.1	0.5	0.5	0.4	1.3	0.5	0.4	0.5		V	0.79	3.34	0.93	1.05	0.7	2.36	0.69	0.54	1.53												H	-2.20	-0.50	-0.10	-1.40	-0.80	-1.20
W	0	-0.1	0	-1.2	-0.1	-0.9	-1.3	0.6	-0.3		W	0.82	2.04	2.52	0.21	0.91	0	0.39	0.35	0.22												I	-1.90	0.05	0.70	-0.10	-0.50	-1.40
Y	0	0.9	0.8	-1	-0.2	-1.1	-0.7	1.3	-1.5		Y	1.07	0.74	1.51	0.39	1.41	0	0.44	0.61	0.35												K	-2.00	-0.30	1.30	-2.40	-1.10	-1.50
	Hammer, et al., JExMed '94, 180:2353											Southwood, et al., JI '98, 160:3363-73																				L	-2.00	0.20	0.20	-1.10	-0.90	-1.00
																																M	-1.80	0.10	-0.90	-1.10	-0.80	-1.50
																																N	-1.10	0.70	-0.60	1.30	-0.60	-1.30
																																P	-0.20	-0.20	0.50	0.00	-0.50	0.20
																																Q	-1.80	-0.80	-0.30	-1.50	-1.10	-1.40
																																R	-1.80	1.00	1.00	-2.40	-1.10	-1.30
																																S	-0.60	0.60	-0.10	1.00	0.60	-0.50
																																T	-1.20	-0.04	0.80	1.90	-0.08	-0.80
																																V	-1.10	-0.30	1.20	0.90	0.10	-1.30
																																W	-2.40	-0.40	-1.40	-1.00	-0.90	-1.70
																																Y	-2.00	0.40	-1.40	-1.50	-1.00	-1.00
																																	Pocket 7
																																	1	2	3	4	5	6	7	8	9	10	11
																																A	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
																																C	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
																																D	-2.00	-0.70	-0.60	-0.30	-2.10	-1.20	-2.70	-1.30	-2.40	-1.50	-1.50
																																E	-0.60	-0.70	-0.20	0.20	-1.20	-0.70	-1.30	0.90	-2.40	-0.90	-1.00
																																F	0.30	1.40	0.50	-1.00	0.50	-0.05	-0.40	2.10	-0.90	1.50	0.60
																																G	-1.10	0.00	0.10	-1.30	-2.10	-1.20	-0.40	0.00	-0.50	0.60	-1.50
																																H	0.10	0.60	-0.80	0.00	0.50	-0.40	-0.20	0.90	-0.90	1.20	0.30
																																I	0.60	1.50	0.40	0.08	0.50	0.08	0.80	2.40	-0.80	1.20	-0.50
																																K	-0.20	-0.30	-0.90	-0.30	0.00	-1.30	-0.20	0.50	-0.80	0.90	0.00
																																L	0.30	1.90	0.20	0.70	1.00	0.30	1.50	2.20	-0.30	0.60	0.40
																																M	0.09	1.70	1.10	0.80	0.80	0.70	1.30	1.80	-0.30	0.40	0.00
																																N	0.10	0.70	-0.09	0.60	0.60	0.70	-1.00	1.40	-1.30	0.50	0.10
																																P	0.07	0.30	0.70	-0.70	-1.00	-1.00	-0.05	-0.20	-1.20	-0.60	-0.50
																																Q	0.20	-0.30	-0.10	0.00	1.10	-0.20	-1.10	1.10	-1.20	0.70	-0.40
																																R	0.09	-0.50	-0.90	-1.20	1.70	-0.90	-0.40	0.70	-0.60	1.30	1.20
																																S	-0.20	0.30	0.07	-0.20	-0.40	0.50	-1.30	0.40	-1.30	-0.20	-0.90
																																T	0.09	0.20	-0.10	-0.10	0.10	0.40	-1.30	0.90	-2.40	0.30	-0.90
																																V	0.70	0.30	0.20	0.08	0.20	-0.10	-0.60	1.60	-1.10	-0.30	-0.10
																																W	-0.08	0.60	-0.60	-1.40	1.40	-0.70	-0.40	1.40	-1.20	0.40	0.40
																																Y	0.50	0.70	-0.05	-1.20	0.90	-0.20	-0.40	1.70	-1.10	1.20	-0.20
																																	Pocket 9
																																	1	2	3	4	5	6
																																A	0.00	0.00	0.00	0.00	0.00	0.00
																																C	0.00	0.00	0.00	0.00	0.00	0.00
																																D	-1.90	-0.60	-1.70	-1.20	1.00	-1.50
																																E	-1.90	-0.30	-1.70	-0.30	1.30	-0.60
																																F	-0.40	0.90	-1.00	2.10	-0.10	1.20
																																G	-0.80	0.40	-1.00	-0.60	0.30	0.40
																																H	-1.10	-0.50	0.08	-0.20	1.30	1.00
																																I	0.70	0.60	-0.30	3.40	-0.10	1.20
																																K	-1.70	-0.20	-0.30	-1.10	-1.00	2.70
																																L	0.50	-0.04	-1.00	3.40	0.00	1.30
																																M	0.08	1.10	-0.40	2.00	0.70	0.50
																																N	-1.20	-0.60	-1.40	-0.50	0.60	0.00
																																P	-1.10	-0.30	-1.30	-0.60	-0.90	-0.80
																																Q	-1.60	-0.20	0.50	-0.90	1.30	0.70
																																R	-1.00	0.50	-1.00	-0.80	-1.00	2.50
																																S	-0.30	1.10	0.70	-0.30	0.70	0.70
																																T	-0.20	-0.50	-1.20	0.40	-0.30	-0.20
																																V	0.30	0.30	-0.70	2.00	-0.40	-0.20
																																W	-1.40	-1.00	-1.00	0.80	-0.10	-0.70
																																Y	-0.90	0.30	-1.00	1.10	0.10	1.30