Welcome to the Baker Lab at MIT - 
Our goal is to understand the mechanism
and regulation of two
classes of macromolecular
machines: the Clp/Hsp100 ATPases that catalyze protein unfolding and
the disassembly of protein complexes, and the tranposase/integrase family
of recombinases that catalyze DNA transposition. These biological catalysts
are being studied using biochemistry, structural biology, molecular
biology, and genetics.
