recent publications

2013

  1. 1.    Su X, Yang N, Wittrup KD, and Irvine DJ, “Synergistic anti-tumor activity from two-stage delivery of targeted toxins and endosome-disrupting nanoparticles,” Biomacromolecules in press. PMCID: Pubmed Central Journal – in process.

  2. 2.     Kwong B, and Irvine DJ, “Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity,” Cancer Res. in press. PMCID: Pubmed Central Journal – in process.

  3. 3.      Ackerman M, Dugast A-S, McAndrew E, Tsoukas S, Licht A, Irvine DJ, and Alter G, “Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b" J. Virology in press. PMCID: Pubmed Central Journal – in process.

  4. 4.     DeMuth PC, Min Y, Huang B, Kramer JA, Miller AD, Barouch DH, Hammond PT, and Irvine DJ, “Polymer multilayer tattooing for enhanced DNA vaccination,” Nature Materials published online Jan 27 (2013). PMCID: Pubmed Central Journal – in process.

  5. 5.   Wang Y and Irvine DJ, “Convolution of chemoattractant secretion rate, source density, and receptor desensitization direct diverse migration patterns in leukocytes,” Integrative Biology 5(3) 481-494 (2013). PMCID: Pubmed Central Journal – in process.

  6. 6.     Mata-Fink J, Kriegsman B, Yu HX, Zhu H, Hanson MC, Irvine DJ, and Wittrup KD, “Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed on Yeast,” J. Mol. Biol. 425 444–456 (2013). PMCID: Pubmed Central Journal – in process.


2012

  1. 1.     Yamanaka YJ, Szeto GL, Gierahn TM, Forcier TL, Benedict KF, Brefo MSN, Lauffenburger DA, Irvine DJ, Love JC, “Cellular barcodes for efficiently profiling single-cell secretory responses by microengraving,” Anal. Chem. online (2012).

  2. 2.   DeMuth PC, Moon JJ, Suh H, Hammond PT, and Irvine DJ, “Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery,” ACS Nano in press.

  3. 3.  DeMuth PC, Garcia-Beltran WF, Ai-Ling ML, Hammond PT, and Irvine DJ, “Composite dissolving microneedles for coordinated control of antigen and adjuvant delivery kinetics in transcutaneous vaccination,” Adv. Funct. Mater. in press.

  4. 4.    Stephan MT, Stephan S, Bak SP, Chen J, and Irvine DJ, “Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles,” Biomaterials. 33(23) 5776-5787 (2012).

  5. 5.    Moon JJ, Huang B, and Irvine DJ, “Engineering nano- and micro-particles to tune immunity,” Advanced Materials. 24(28) 3724-3746 (2012).

  6. 6.     Moon JJ, Suh H, Li AV, Ockenhouse CF, Yadava A, and Irvine DJ, “Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction,” Proc. Natl. Acad. Sci., U.S.A. 109 1080-1085 (2012).

  7. 7.    Moon JJ, Suh H, Polhemus ME, Ockenhouse CF, Yadava A, and Irvine DJ, “Antigen-displaying lipid-enveloped PLGA nanoparticles as delivery agents for a Plasmodium vivax malaria vaccine,” PLoS ONE 7, e31472 (2012).

  8. 8.      Bershteyn A, Hanson MC, Crespo MP, Moon JJ, Li AV, Suh H, and Irvine DJ, “Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine,” Journal of Controlled Release 157 3543-365 (2012).

  9. 9.   Metallo CM, Gameiro PA, Bell EL, Mattaini KR, Yang J, Hiller K, Jewell CM, Johnson ZR, Irvine DJ, Guarente L, Kelleher JK, Vander Heiden MG, Iliopoulos O, and Stephanopoulos G, “Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia,” Nature 481, 380–384 (2012).


Full publication list