recent publications

2014

  1. 1.      Hanson MC, Bershteyn A, Crespo MP, and Irvine DJ, “Antigen Delivery by Lipid-enveloped PLGA Microparticle Vaccines Mediated by in situ Vesicle Shedding,” Biomacromolecules in press.  Pubmed Central Journal – in process

  2. 2.      Liu H, Moynihan KD, Zheng Y, Szeto GL, Li AV, Huang B, Van Egeren DS, Park C, and Irvine DJ, “Structure-based programming of lymph node targeting in molecular vaccines,” Nature 507 519–522 (2014). Pubmed Central Journal – in process

  3. 3.      Foley MH, Forcier T, McAndrew E, Gonzalez M, Chen H, Juelg B, Walker BD, and Irvine DJ, “High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function,” PLoS ONE 9 e87873 (2014). Pubmed Central Journal – in process

  4. 4.      DeMuth PC, Min Y, Irvine DJ, and Hammond PT, “Implantable silk composite microneedles for programmable vaccine release kinetics and enhanced immunogenicity in transcutaneous immunization,” Advanced Healthcare Materials 3(1) 47-58 (2014). PMCID:PMC3950936


2013

  1. 1.      DeMuth PC, Li AV, Abbink P, Liu J, Li H, Stanley KA, Smith KM, Lavine CL, Seaman MS, Kramer JA, Miller AD, Abraham W, Suh H, Elkhader J, Hammond PT, Barouch DH, and Irvine DJ, “Immunogenic delivery of adenoviral vectors in non-human primates from microneedle skin-patches,” Nature Biotechnology 31 1082-1085 (2013). PMC Journal – in process

  2. 2.      Irvine DJ, Swartz MA, and Szeto GL, “Engineering synthetic vaccines using cues from natural immunity,” Nature Materials 12(11) 978-990 (2013). Pubmed Central Journal – in process

  3. 3.      Li AV, Moon JJ, Abraham W, Suh H, Elkhader J, Seidman MA, Yen M, Im EJ, Foley MH, Barouch DH, and Irvine DJ, “Generation of effector memory T-cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination,” Science Translational Medicine 5 204ra130 (2013). PMC Journal – in process

  4. 4.      Drake A, Joshi NS, Szeto GL, Zhu EF, Eisen HN, and Irvine DJ, “Koch Institute symposium on cancer immunology and immunotherapy,” Cancer Immunology Research 1(4) 217-222 (2013).  PMCID: Pubmed Central Journal – in process.

  5. 5.      Kim M, Song L, Moon J, Sun Z-YJ, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, and Reinherze E, “Immunogenicity of membrane-bound HIV-1 gp41 MPER segments is dominated by residue accessibility and modulated by stereochemistry,” Journal of Biological Chemistry published online Sept 18 (2013). PMCID: Pubmed Central Journal – in process.

  6. 6.      Van Lehn RC, Atukorale PU, Carney RP, Yang Y-S, Stellacci F, Irvine DJ, and Alexander-Katz A, “Effect of Particle Diameter and Surface Composition on the Spontaneous Fusion of Monolayer-Protected Gold Nanoparticles with Lipid Bilayers,” Nano Letters 13 4060-4067 (2013). PMCID: Pubmed Central Journal – in process.

  7. 7.      Zheng Y, Stephan M, Gai SA, Abraham W, Shearer A, and Irvine DJ, “In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes,” Journal of Controlled Release in press.  PMCID: Pubmed Central Journal – in process.

  8. 8.      Su X, Yang N, Wittrup KD, and Irvine DJ, “Synergistic anti-tumor activity from two-stage delivery of targeted toxins and endosome-disrupting nanoparticles,” Biomacromolecules 14(4) 1093-1102 (2013). PMCID: Pubmed Central Journal – in process.

  9. 9.      Kwong B, and Irvine DJ, “Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity,” Cancer Res. 73(5) 1547–58 (2013). PMCID: Pubmed Central Journal – in process.

  10. 10.     Ackerman M, Dugast A-S, McAndrew E, Tsoukas S, Licht A, Irvine DJ, and Alter G, “Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b" J. Virology in press. PMCID: Pubmed Central Journal – in process.

  11. 11.    DeMuth PC, Min Y, Huang B, Kramer JA, Miller AD, Barouch DH, Hammond PT, and Irvine DJ, “Polymer multilayer tattooing for enhanced DNA vaccination,” Nature Materials 12 367–376 (2013). PMCID: Pubmed Central Journal – in process.

  12. 12.    Wang Y and Irvine DJ, “Convolution of chemoattractant secretion rate, source density, and receptor desensitization direct diverse migration patterns in leukocytes,” Integrative Biology 5(3) 481-494 (2013). PMCID: Pubmed Central Journal – in process.

  13. 13.    Mata-Fink J, Kriegsman B, Yu HX, Zhu H, Hanson MC, Irvine DJ, and Wittrup KD, “Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed on Yeast,” J. Mol. Biol. 425 444–456 (2013). PMCID: Pubmed Central Journal – in process.


Full publication list