2010-

  1. Ciaccio M.F., J.P. Wagner, C.-P. Chuu, D.A. Lauffenburger, and R.B. Jones, “Systems Analysis of EGF Receptor Signaling Dynamics with Micro-Western Arrays”, Nature Methods 7: 148-155 (2010).
  2. Kreeger, P.K., Y. Wang, K.M. Haigis, and D.A. Lauffenburger, “Integration of Multiple Signaling Pathway Activities Resolves K-Ras/N-Ras Mutation Paradox in Colon Epithelial Cell Response to Inflammatory Cytokine Stimulation”, Integrative Biology 2: 202-208 (2010).
  3. Lazzara, M.J., K. Lane, R. Chan, P.J. Jasper, M.B. Yaffe, P.K. Sorger, T. Jacks, B.G. Neel, and D.A. Lauffenburger, “Impaired SHP2-Mediated ERK Activation Contributes to Gefitinib Sensitivity of Lung Cancer Cells with EGFR-Activating Mutations”, Cancer Res. 70: 3843-3850 (2010).
  4. Das, A., D.A. Lauffenburger, H. Asada, and R.D. Kamm, “A Hybrid Continuum-Discrete Modelling Approach to Predict and Control Angiogenesis: Analysis of Combinatorial Growth Factor and Matrix Effects on Vessel-Sprouting Morphology”, Phil. Trans. Roy. Soc. A 368: 2937-2960 (2010).
  5. Prince, R.N., E.R. Schreiter, P. Zou, H.S. Wiley, A.Y. Ting, R.T. Lee, and D.A. Lauffenburger, “The Heparin-Binding Domain of HB-EGF Mediates Localization to Cell-Cell Contact Sites and Prevents HB-EGF Release”, J. Cell Sci. 123: 2308-2318 (2010).
  6. Cosgrove, B.D., L.G. Alexopoulos, T.-c. Hang, B.S. Hendriks, P.K. Sorger, L.G. Griffith, and D.A. Lauffenburger, “Cytokine-Associated Drug Toxicity in Human Hepatocytes is Associated with Signaling Network Dysregulation”, Molec. BioSyst. (in press, 2010).
  7. Joslin, E.J., H. Shankaran, L.K. Opresko, N. Bollinger, D.A. Lauffenburger, and H.S. Wiley, “Structure of the EGF Receptor Transactivation Circuit Integrates Multiple Signals with Cell Context”, Molec. BioSyst. (in press, 2010).
  8. Alexopoulos, L.G., J. Saez-Rodriguez, B.D. Cosgrove, D.A. Lauffenburger, and P.K. Sorger, “Networks Inferred from Biochemical Data Reveal Profound Differences in TLR and Inflammatory Signaling Between Normal and Transformed Hepatocytes”, Molec. Cell. Proteomics (in press, 2010).
  9. Espelin, C.W., A. Goldsipe, P.K. Sorger, D.A. Lauffenburger, D. de Graaf, and B.S. Hendriks, “Elevated GM-CSF and IL-1β Levels Compromise the Ability of p38 MAPK Inhibitors to Modulate TNFα Levels in the Human Monocytic/Macrophage U937 Cell Line”, Molec. BioSyst. (accepted for publication, 2010).
  10. Spangler, J.B., J.R. Neil, S. Abramovitch, Y. Yarden, F.M. White, D.A. Lauffenburger, and K.D. Wittrup, “Combination Antibody Treatment Downregulates EGF Receptor by Inhibiting Endosomal Recycling”, Proc. Natl. Acad. Sci. USA (accepted for publication)

 

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