- Z.-Y. J. Sun, K. J. Oh, M. Kim, M. Adamowicz, J. West, J. Yu, V. Brusic, Z. Qiao, J.-h. Wang, G. Wagner, E. L. Reinherz: HIV-1 broadly neutralizing antibody extracts its epitope from a kinked MPER segment on the viral membrane, Immunity, 28, 52-63 (January 2008).
- D. P. Frueh, H. Arthanari, A. Koglin, D. Vosburg, A. E. Bennett, C. T. Walsh, and G. Wagner, Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase. Nature, 454, 903-906 (2008), PMC2597408.
- A. Koglin, F. Löhr, F. Bernhard, V. Rogov, D. P. Frueh, P. Güntert, G. Wagner, C. T. Walsh, M. A. Marahiel and V. Dötsch: Structural basis for the selectivity of the external thioesterase of the surfactin synthetase. Nature, 454, 907-911 (2008). PMC2854587.
- S. Kang, J. Kang, H. Kwon, D. Frueh, S. Hyun Yoo, G. Wagner, and S. Park: Effects of redox potential and Ca2+ on the inositol 1,4,5-trisphosphate receptor L3-1 loop region: implications for receptor regulation, J.Biol. Chem., 283, 25567-25575 (2008). PMC Journal - PMCID In Process.
- C. Suzuki, R. Garces, K. Edmonds, S. Hiller, S. Hyberts, A. Marintchev, G. Wagner: PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. PNAS 105,3274-3279 (2008). PMC2265113
- J. K. Thakur, H. Arthanari, F. Yang, S.-J. Pan, X. Fan, J. Breger, D. P. Frueh, K. Gulshan, D. Li, E. Mylonakis, K. Struhl, W. S. Moye-Rowley, B. P. Cormack, G. Wagner, A. M. Näär: A Nuclear Receptor-Like Pathway Regulating Multidrug Resistance in Fungi. Nature, 452, 604-609 (2008).
- P. Selenko, D. P. Frueh, S. J. Elsaesser, W. Haas, S. P. Gygi, G. Wagner: In situ observation of protein phosphorylation by high-resolution NMR spectroscopy. NSMB, 15, 321-329 (2008).
- A. Catic, Z.-Y. J Sun, D.M Ratner, S. Misaghi, E. Spooner, J. Samuelson, G. Wagner, H.L Ploegh: Sequence and structure evolved separately in a ribosomal ubiquitin variant. EMBO J. 26, 3474 - 3483 (2007).
- K. Takeuchi; H. Yang; E. Ng; S. Park; Z.-Y. J. Sun; Ellis L Reinherz; Gerhard Wagner: Structure of the CD3e-Nck complex and its role in TCR signaling and internalization. J. Mol. Biol., 380,704-716 (2008), PMC2577852.
- G. Wagner: Introduction: NMR Resonance in Undergraduate Education. Chapter 1, Modern NMR Spectroscopy in Education. D. Rovnyak, R. Stockland Jr. (eds.) American Chemical Society,Washington DC, (2007).
- Moerke N.J., Fahmy A., Degterev A., Harbinski F., Gross J.D., Aktas H., Halperin J.A., Wagner G. “Identification of small molecule inhibitors of eIF4E complex formation”, Clinical Cancer Research 9 (16): 6170S-6170S Part 2 Suppl. S, Dec. 2003.
- H. Arthanari, D. Frueh, G. Wagner, B. Pryor, N. Khaneja: Fourier synthesis techniques for NMR spectroscopy in iomogenous fields. J. Chem. Phys, 128, 21503 (2008). PMC Journal - PMCID In Process.
- L. Lindqvist, M. Oberer, M. Reibarkh, R. Cencic, M.-E. Bordeleau, E. Vogt, A. Marintchev, J. Tanaka, F. Fagotto, M. Altmann, G. Wagner, J. Pelletier: Selective Pharmacological Targeting of a DEAD box RNA helicase, PLoS ONE, 3, e1583 (2008). PMC2216682
- Degterev, J. Hitomi, M. Germscheid, I. Ch’en, O. Korkina, X. Teng, D. Abbott, G. D. Cuny, C. Yuan, G. Wagner, S. M. Hedrick, S. A. Gerber, A. Lugovskoy & J. Yuan: Identification Of Rip1 Kinase As A Specific Cellular Target Of Necrostatins. Nature Chem. Biol., 4, 313-321 (2008). PMC: Accepted for publication Mar. 6, 2008.
- S. Hiller, R. G. Garces, T. J. Malia, V. Y. Orekhov, M. Colombini, G. Wagner: Solution structure of the integral human membrane protein VDAC-1 in detergent micelles, Science 321, 1206- 1210 (2008). PMC2579273.
- Marintchev, K. A. Edmonds, B. Marintcheva, E. Hendrickson, M. Oberer, C. Suzuki, B. Herdy, N. Sonenberg, G. Wagner: The topology of the human eIF4A/4G/4H complex and the regulation of helicase activity, Cell, 136, 447-460. (2009), PMC2656774.
- M. Hemond, T. L. Rothstein, G. Wagner: Fas Apoptosis Inhibitory Molecule (FAIM) contains a novel beta sandwich in contact with a partially ordered domain J. Mol. Biol., 386, 1024-1037 (2009). DOI: 10.1016/j.jmb.2009.01.004. PMC274528
- S. T. Kim, K. Takeuchi, Z.-Y. J. Sun, M. Touma, C. E. Castro, A. Fahmy, V. P. Dave, D. J. Kappes, M. J. Lang, G. Wagner, E. L. Reinherz: The ab T cell receptor is an anisotropic mechanosensor J. Biol.Chem. 284, 31028-31037 (2009). PMC2781503
- M. Billeter, G. Wagner, K. Wüthrich: Solution NMR structure determination of proteins revisited, J. Biomol. NMR, 42, 155-158 (2008), PMC2748914
- K. Takeuchi, Z.-Y. J. Sun, G. Wagner: Alternate 13C-12C labeling for complete mainchain resonance assignments using C alpha direct-detection with applicability toward fast relaxing protein systems. J. Am. Chem. Soc., 130, 17210-17211 (2008), PMC2626166
- J. K. Thakur, H. Arthanari, F. Yang, G. Wagner, A. M. Näär: Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast nuclear receptor-like transcription factor Oaf1p, JBC, 284, 4422-4428 (2009). PMC Journal – Free Article.
- Y. Yoffe, M. Léger, A. Zinoviev, J. Zuberek, E. Darzynkiewicz, G. Wagner, M. Shapira: Evolutionary adaptation of the Leishmania eIF4F complex to cap-4 binding involves changes in the eIF4E-eIF4G interactions, Nucleic Acid Res, 37, 3243-3253, (2009) Epub 2009 Mar 24, PMC2691829
- L. Song, Z-Y. J. Sun, K. E. Coleman, M. Zwick, J. Gach, J.-H. Wang, E. L. Reinherz, G. Wagner, M. Kim: Broadly neutralizing anit-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface. PNAS, 22, 9057-9062, (2009), PMC2690059
- S. Hiller, H. Arthanari, G. Wagner: The T-lock: Automated compensation of radio-frequency induced sample heating. J.Biomol.NMR, 44 (2) 69-76 (2009). PMC2733869
- S. Hiller, G.Wagner: The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins. Curr. Opin. Struct. Biol., 19, 396-401 (2009). PMCID2739811
- S. Hiller, I. Ibragimov, G. Wagner, V. Orekhov: Complete decomposition of four-dimensional NOESY spectra, J Am Chem Soc. 131, 12970-12978 (2009). PMC2771277
- S. G. Hyberts, D. P. Frueh, H. Arthanari, G. Wagner: FM reconstruction of non-uniformly sampled protein NMR data at higher dimensions and optimization by distillation, J. Biomol. NMR, 45, 283-294 (2009). PMC2858293
- D. P. Frueh, H. Arthanari, A. Koglin, C.T. Walsh, G. Wagner: A double TROSY hNCAnH experiment for efficient assignment of large and challenging proteins, J. Am. Chem. Soc., 131, 12880-12881 (2009). PMC2749991
- D. P. Frueh, A. Leed, H. Arthanari, A. Koglin, C. T. Walsh, G. Wagner: Time-shared HSQC-NOESY for accurate distance constraints measured at high-field in 15N-13C-ILV methyl labeled proteins, J. Biomol. NMR, 45, 311-318 (2009). PMC2778061
- T. Raschle, S. Hiller, T.Y. Yu, A.J. Rice, T. Walz, G. Wagner: Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs. J Am Chem Soc. 131,17777-17779 (2009). PMC2793270
- Wagner, G.: A topical issue: production and labeling of biological macromolecules for NMR investigations. J Biomol NMR 46, 1–2 (2010). Editorial.
- Zhou P, Wagner: Overcoming the solubility limit with solubility-enhancement tags: successful applications in biomolecular NMR studies. J Biomol NMR 46, 23–31 (2010). PMC2879018
- Takeuchi, K, Frueh, DP, Hyberts, SG, Sun, Z-Y, Wagner, G: High-resolution 3D CANCA NMR experiments for complete mainchain assignments using Ca direct-detection. J Am Chem Soc., 132, 2945-2951 (2010). PMC2832079
- S.G. Hyberts, K. Takeuchi, G. Wagner: Poisson-Gap Sampling and FM Reconstruction for Enhancing Resolution and Sensitivity of Protein NMR Data. J Am Chem Soc., 132, 2945-2951 (2010). PMC2825045
- Y. Yu, A. Marintchev, V.G. Kolupaeva, A. Unbehaun, T. Veryasova, S.C. Lai, P. Hong, G. Wagner, C.U.Hellen, T.V. Pestova: Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing. Nucleic Acid Res. 37, 5176-5182 (2009). PMC2731904
- S. Hiller, J. Abramson, C. Mannella, G. Wagner, K. Zeth: The 3D structures of VDAC represent a native conformation. Trends Biochem. Sci., 35, 514-521 (2010). PMC2933295
- K. Takeuchi, D. P. Frueh, Z.-Yu J. Sun, S. Hiller, G. Wagner: CACA-TOCSY with alternate 13C-12C labeling: a 13C direct detection experiment for mainchain resonance assignment, dihedral angle information, and amino acid type identification. J. Biomol. NMR, 47, 55-63 (2010). PMC2868269
- K. Takeuchi, Z.-Y. Sun, S. Park, G. Wagner: Auto-inhibitory interaction in multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity, Biochemistry, 49, 5634-5641 (2010). PMC2899887
- K. Takeuchi, G. Heffron, Z.-Yu J. Sun, D.P. Frueh, G. Wagner: Nitrogen-detected CAN and CON experiments as alternative experiments for main chain NMR resonance assignments. J. Biomol. NMR, 47, 271-282 (2010). PMC2946331
- S. Hiller, G. Wagner: Solution NMR Spectroscopy of Integral Membrane Proteins. Comprehensive Biophysics, Chapter 5.8: Solution NMR of Integral Membrane Proteins,
In: Edward H. Egelman, editor: Comprehensive Biophysics, Vol 5, Membranes, Lukas Tamm. Oxford: Academic Press, 2012. pp. 120-138.
- S.T. Kim, M. Touma, K. Takeuchi, Z.-Y. Sun, V.P. Dave, D. J. Kappes, G. Wagner, E. L. Reinherz: Distinctive CD3 Heterodimeric Ectodomain Topologies Maximize Antigen-triggered Activation of αβ T Cell Receptors, J. Immunology, 185, 2951-2959 (2010). PMC2936104
- M. G. Van der Heiden, J. W. Locasale, K. D. Swanson, H. Sharfi, G.J. Heffron, D. Amador-Noguez, H. R. Christofk, G. Wagner, J. D. Rabinowitz, J. M. Asara, L. C. Cantley: Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science, 329 1492-1499 (2010). PMC3030121.
- S. Kang, H. Kwon, H. Wen, Y. Song, D. Frueh, H.-C. Ahn, S. H. Yoo, G. Wagner, S. Park: Global dynamic conformational changes in the suppressor domain of IP3 receptor by stepwise binding of the two lobes of calmodulin. FASEB J., 25, 840-850 (2011). PMC Journal - In Process.
- F. Shaw, H. Arthanari, M. Narovlyansky, A. Durazo, D. P. Frueh, M. P. Pollastri, A. Lee, B. Bilgicer, S. P. Gygi, G. Wagner, G. M. Whitesides: Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability. J. Amer. Chem. Soc., 132,17411-17425 (2010) PMC3135700
- K. Takeuchi, M. Gal, H. Takahashi, I. Shimada, G. Wagner: HNCA-TOCSY-CANH experiments with alternate 13C-12C labeling: a set of 3D experiment with unique supra-sequential information for mainchain resonance assignment. J. Biomol. NMR, 49, 17-26 (2011). PMC3072286
- J.-S. Li, J. Ruths, T.-Y. Yu, H. Arthanari, G. Wagner: Optimal pulse design in quantum control: A unified computational method. PNAS, 108, 1879-1884 (2011) PMC Journal – Free Article.
- G. Milbradt, M. Kulkarni, T. Yi, K. Takeuchi, Z.-Y. J. Sun, R. E. Luna, P. Selenko, A. M. Näär, G. Wagner: Structure of the VP16 Transactivator Target in ARC/Mediator, Nature Str. & Mol. Biology, 18, 410-415 (2011). PMC3076674
- Arthanari, G. Wagner, N. Khaneja: Heteronuclear Decoupling by Multiple Rotating Frame Technique”, J. Magn. Reson., 209, 8-18 (2011). PMC3101322
- S. G. Hyberts, H. Arthanari, G. Wagner, "Wagner, G: Applications of non-uniform sampling and processing. Top. Curr. Chem., 316, 125-148 (2012).
- T. Raschle, S. Hiller, M. Etzkorn, G. Wagner Nonmicellar systems for solution NMR spectroscopy of membrane proteins. Curr Opin Struct Biol. 20, 471-479 (2010) PMC2928847
Miaoa, I. Skidan, J. Yang, A. Lugovskoy, M. Reibarkh, K.Long, T. Brazell, K.A. Durugkar, J. Maki, C. V. Ramana, B. Schaffhausen, G.Wagner, V. Torchilin, J.Yuan, A. Degterev: Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains. PNAS, 107, 20126-20131 (2010). PMC2993381
- A. Hoeffer, K. K. Cowansage, E.C. Arnold, J. L Banko, N. J. Moerke, R. Rodriguez, E. K. Schmidt, E. Klosi , M. Chorev, R. E. Lloyd, P. Pierre, G. Wagner, J. E. LeDoux, E. Klann: Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. PNAS, 108, 3383-3388 (2011). PMC3044415
- Zinoviev, M. Léger, G. Wagner, M. Shapira: A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways. Nucleic Acid Res, 39, 8404-8415 (2011). PMC Journal – Free Access.
- Yi, I.-H. Jang, H. Pan, J. Seebacher, S. G. Hyberts, G. J. Heffron, M.G. Vander Heiden, R. Yang, F. Li, J. W. Locasale, H. Sharfi, B. Zhai, R. Rodriguez-Mias, H. Luithardt, L. C. Cantley, G. Q. Daley, J. M. Asara, S.P. Gygi, G. Wagner, C.-F. Liu, J. Yuan: Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival, Cell, 146, 607-620 (2011). PMC3182480
- Fahmy, G. Wagner: Optimization of van Der Waals energy for protein side-chain placement and design. Biophysical J., 101, 1690-1698 (2011). (PMC Journal – In Process)
- B.F. Shaw, G. Schneider, H. Arthanari, M. Narovlyansky, D. Moustakas, A. Durazo, G. Wagner, G. Whitesides: Complexes of native Ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants. JACS, October 13 (2011). [Epub ahead of print] PMID: 21939262
- Kim, Z.-Y.J Sun, K. D. Rand, X. Shi, L. Song, Y. Cheng, A. F. Fahmy, S. Majumdar, G. Ofek, Y. Yang, P. D. Kwong, J.-H. Wang, J. R Engen, G. Wagner, E.L Reinherz: Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization. Nature Str. & Mol. Biology, 18, 1235-1234 (2011).
- S. Narayanan, H. Arthanari, M. Wolfe, G. Wagner: Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly. J. Biol. Chem., (2011). published October 13, 2011 as doi:10.1074/jbc.M111.271593
- Gal, K. A. Edmonds, A. G. Milbradt, K. Takeuchi, G. Wagner: Speeding up 15N detection: hCaN 2D NMR experiment. J. Biomol. NMR, 51, 497-504 (2011).
- B.H. Aktas, J.A. Halperin, G. Wagner, M. Chorev: Inhibition of Translation Initiation as a Novel Paradigm for Cancer Therapy. Ann. Rep. in Med. Chem. 46, 189-210 (2011).
- S. T. Kim, Y. Shin, K. Brazin, R. J. Mallis, J. Sun, G. Wagner, M.W. Lang, E. L Reinherz: TCR mechanobiology: Torques and tunable structures linked to early T cell signaling. Frontiers in T Cell Biology, in press.
- S.G. Hyberts, A.G. Milbradt, A.B. Wagner, H. Arthanari, G. Wagner: Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling. J. Biomol. NMR, 52, 315-27 (2012).
- R.E. Luna, H. Arthanari , H. Hiraishi, J. Nanda, P. Martin-Marcos, M. A. Markus, B. Akabayov, A. G. Milbradt, L. E. Luna, H.-C. Seo, S. G. Hyberts, A. Farmy, M. Reibarkh, D. Miles, P. R. Hagner, E. M. O’Day, T. Yi, A. Marintchev, A. Hinnebusch, J. Lorsch, K. Asano, G. Wagner: C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2. Cell Reports, in press. NIHMSID # 373329
- K. Takeuchi, M. Gal, I. Shimada, G. Wagner: Low detection experiments for biomolecular NMR. In “Recent developments in Biomolecular NMR” . M.C. Clore, J. Potts, editors, in press.
- T.-Y. Yu, T. Raschle, S. Hiller, G. Wagner: Solution NMR Spectroscopic Characterization of Human VDAC-2 in Detergent Micelles and Lipid Bilayer Nanodiscs. Biochim Biophys Acta. 1818,1562-1569 (2012). PMC3321126
- M.T. Eddy, T.C. Ong, L. Clark, O. Teijido, P.C. van der Wel, R. Garces, G. Wagner, T.K. Rostovtseva, R.G. Griffin: Lipid dynamics and protein-lipid interactions in 2D crystals formed with the ?-barrel integral membrane protein VDAC1. J. Am. Chem. Soc. 134, 6375-6387 (2012). PMC333839.
- L. Chen, B.H. Aktas, Y. Wang, X. He, R. Sahoo, N. Zhang, S. Denoyelle, E. Kabha, H. Yang, R.Y. Freedman, J.G. Supko, M. Chorev, G. Wagner, J.A. Halperin: Tumor suppression by small molecule inhibitors of translation initiation. Oncotarget 3, 869-881 (2012). Free Journal.
- J.C. Schmidt, H. Arthanari, A. Boeszoermenyi, N. M. Dashkevich, E. M. Wilson-Kubalek, N. Monnier, M. Markus, M. Oberer, R. A. Milligan, M. Bathe5, G. Wagner, E.a L. Grishchuk, I. M. Cheeseman: The kinetochore-bound Ska1 complex tracks depolymerizing microtubules by binding to curved protofilaments. Develop. Cell, Nov 13;23(5):968-80. doi: 10.1016/j.devcel.2012.09.012. Epub 2012 Oct 18. (2012)
- P. Coote, H. Arthanari, T. Yu, A. Natarajan, G. Wagner, N. Khaneja: Pulse design for broadband correlation NMR spectroscopy by multi-rotating frames. J. Biomol. NMR, 55, 291-302 (2013) Feb 19. [Epub ahead of print]
- S. G. Hyberts, S.A. Robson, G. Wagner: Exploring signal-to-noise ratio and sensitivity in non-uniformly sampled multi-dimensional NMR spectra. J Biomol NMR. 55, 167-78 (2013) PMC3570699
- A. J. Wommack, S. A. Robson, Y. A. Wanniarahchi, A. Wan, C. J. Turner, G. Wagner, E. M. Nolan. NMR Solution Structure Determination and Analytical Ultracentrifugation Studies of the Antimicrobial Peptide Human Defensin. Biochemistry, 51, 9624-9634 (2012) PMC3579768
- F. Hagn, M. Etzkorn, T. Raschle, G. Wagner: Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins, JACS, 135, 1919-1925 (2013). PMC3566289
- M. Etzkorn, T. Raschle, F. Hagn, V. Gelev, A.T. Rice, T. Walz, G. Wagner: Cell-Free Expressed Bacteriorhodopsin in Different Soluble Membrane Mimetics: Biophysical Properties and NMR Accessibility, Structure, 21, 394-401 (2013doi:pii: S0969-2126(13)00009-9. 10.1016/j.str.2013.01.005. [Epub ahead of print] PMID: 23415558, PMC3595385.
- S. Akabyov, G. Wagner: Backbone resonance assignment of the HEAT1-domain of the human eukaryotic translation initiation factor 4GI, J. Biomolec. Assignments, 2013 Jan 17. [Epub ahead of print] PMID: 23325513, PMC3640741
- B. Akabayov, S. R. Akabayov, S.–J. Lee, G. Wagner, C. C. Richardson: Impact of macromolecular crowding on DNA replication. Nature Communications 4, 1615, (2013). doi: 10.1038/ncomms2620. NIHMSID 448127
- T. Yi, E. Papadopoulos, G. Wagner: HIF-1α promotes cap-dependent translation of selective mRNAs through upregulating eIF4E1 in breast cancer cells under hypoxia conditions. J. Biol. Chem., 288, 18732-42, (2013) PMC3696647
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