| Family | Zebrafish Gene | Phenotypic Description | Image #1 | Image #2 | Image #3 | Image #4 |
| hi1942 | RNA polymerase III 39kDa subunit | day 3: slightly smaller head and eyes; day 5: small head and eyes, a little pericardial edema, underdeveloped liver/gut |  | | | |
| hi1950 | splicesome-associated factor 61 | day 1: cns necrosis; day 2 very bad necrosis; embryos become increasingly necrotic and die day 3-5 |  | | | |
| hi1951 | RAE1 homolog (RNA export) | day 3: slightly smaller head and eyes; day 5: small head and eyes, a little pericardial edema, underdeveloped liver/gut |  |  | | |
| hi1974 | 40S ribosomal protein s8 | day 1: slightly pinched midbrain/hindbrain boundary, a little cns necrosis, day 2: small head, some cns necr, inflated hindbrain ventricle, thin yolk extension; day 5: very small head and eyes, underdeveloped liver/gut, thin body |  |  |  | |
| hi1987 | 60s ribosomal protein L19 | day 1: slightly pinched midbrain/hindbrain boundary, a little cns necrosis, day 2: small head, some cns necr, a inflated hindbrain ventricle, thin yolk extension; day 5: very small head and eyes, round grey yolk, thin/wasting body, underdeveloped guts, sometimes dead |  |  |  | |
| hi1988 | v-atpase subunit F | day 2: no body pigment, less eye pigment; d5: less pigment, small and blocky head with some necrosis, small eye, underdeveloped liver/gut, a little pericardial edema |  |  |  | |
| hi2026a | inhibitor of apoptosis protein with a caspsase recruitment domain | day 4-5: somewhat dark/necrotic head, pericardial edema, some degeneration in body |  | | | |
| hi2039a | synembryn-like | day 2: a little less pigment, pigment in tighter spots ; day 5: rounder head, thick jaw, a bit smaller eye, smaller/tighter pigment spots, sometimes inflate swim bladder |  |  |  | |
| hi2062 | cdc37-like | day 3: a little cns necrosis, a bit smaller head, pericardial edema; day 4-5: necrosis in body, small head and eyes, pericardial edema, underdeveloped liver/gut, unconsumed yolk |  |  | | |
| hi2078 | nucleolin | day 1: slightly pinched midbrain/hindbrain boundary, a little cns necrosis, day 2: slightly smaller head; day 5: small head and eyes, pericardial edema, underdeveloped liver/gut |  |  |  | |
| hi2080 | NDC80 / HEC (highly expressed in cancer) | day 1: cns necrosis, flat head; day 2 very bad necrosis; embryos become increasingly necrotic and die day 3-5 |  |  | | |
| hi2091 | RING+BBOX zinc finger protein | day 1: cells appear to be shedding off; day 2: more severe, maybe dying/rotting. Usually totally rotten by day 2-3 |  |  |  | |
| hi2092 | caudal | day 1: short body (almost nothing past yolk); later days: short body, also develops cystic kidney |  |  | | |
| hi2109 | tbx16/spadetail | day 1: anterior trunk is thinner with indistinct notochord and somite boundaries, sometimes yolk is pinched where extension meets yolk, trunk is a bit broad just posterior to that; day 2: head a bit short A-P, tall D-V; anterior trunk thin, posterior of trunk a little bulbous; day 5: head looks swollen, a little pericardial edema, anterior trunk still thin and/or kinked with disruptions in notochord and somites, underdeveloped liver/ gut |  |  | | |
| hi2143 | EXML1 | day 5: slightly smaller and rounder head, a bit of pericardial edema, underdeveloped liver/ gut |  | | | |
| hi2151 | novel (pan-epithelial glycoprotein) | day 2-3: small otoliths. Indistinguishable from wild type by day 5 |  |  |  | |
| hi2155 | novel (FLJ12949-like) | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped liver/gut, a little pericardial edema |  |  |  | |
| hi2188b | v-atpase AC39 subunit | day 2: no/less body pigment, head a little shorter/blockier; day 5: less body pigment, body a little thinner, gut slightly underdeveloped |  |  |  | |
| hi2211 | IFT172 / LIM-interacting protein | day 2: ventrally curved body, small kidney cyst; day 5, curved or wavy body, kidney cyst |  | | | |
| hi2216 | glutaminyl-tRNA synthetase | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped liver/gut, a little pericardial edema |  | | | |
| hi2217 | serine protease inhibitor HGFAI | day 2: fins seem not so full; head, eyes and/or body sometimes a little smaller; day 5: fins small and very rough edged, head, eyes and/or body sometimes a little smaller, sometimes do inflate swim bladder - these are viable, and have normal fins within a few weeks |  |  | | |
| hi2226 | nagie oko (MAGUK family) | day 1: brain folds are irregular, hindbrain ventricle underinflated; day 2: small, bumpy head, pericardial edema, trunk bent dorsally; day 5: a bit smaller, bumpy head, a bit of pericardial edema, severely curved trunk |  |  |  | |
| hi2230 | eukaryotic translation initiation factor 3, subunit 7 | day 2: a little cns necrosis, a little smaller head and eyes; day 5: small head and eyes, pericardial edema, round grey yolk, underdeveloped liver/gut, sometimes dead |  | | | |
| hi2246 | novel (FLJ11294-like) | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped liver/gut, pericardial edema |  |  | | |
| hi2271 | Splicing factor 3B subunit 10 | day 2: cns necrosis, small head and eyes, inflated hindbrain ventricle, thin and often curved body, rounder yolk with no extension; days 3-5, necrosis spreads throughout body, body wasting, small head and eyes and body, edema (pericardial and elsewhere), some dead by day 5 |  |  | | |
| hi2285 | syntaxin binding protein 3 | days 3-5: slightly smaller and rounder head, very small ears and otoliths, shorter body, a bit of pericardial edema, slightly underdeveloped gut |  |  | | |
| hi2289 | DEAD/H box 51 RNA helicase | day 3: begin small head/eye; day 5: small head/eye, underdev guts, sometimes a little pc edema |  | | | |
| hi2293 | chordino | day 1: slightly short trunk, ventral trunk thickened just posterior to yolk; day 2-5: tail tip bent up a bit, still thickened ventral trunk |  |  | | |
| hi2329a | novel (KIAA0682-like) | day 5: slightly narrow head, slightly underdeveloped gut |  | | | |
| hi2335 | phospholipase C gamma 1 | day 2: head and eyes a little smaller, pericardial edema; day 5: smaller head and eyes, pericardial edema and other edema, body bent up and/or necrotic |  |  |  | |
| hi2345 | novel (GTP binding protein NGB) | day 2: a little cns necrosis, inflated hindbrain ventricle, thin yolk extension; day 5: small head and eyes, round grey yolk, thin body underdeveloped liver/gut |  |  | | |
| hi2393 | RNA polymerase I polypeptide D | day 2: mild cns necrosis; day 3: small head and eyes, round yolk; day 5: small head and eyes, pericardial edema, underdeveloped liver/gut |  |  | | |
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