Family | Zebrafish Gene | Phenotypic Description | Image #1 | Image #2 | Image #3 | Image #4 |
hi2394 | reptin | day 2: body bent ventrally; days 3-4, cns necrosis, small head and eyes, pericardial edema, body stays ventrally curved, kidney cyst develops; day 5: kidney cyst larger; necrosis begins to spread through body | | | | |
hi2404 | novel (AK022581-like) | day 1: pinched midbrain/hindbrain boundary, a bit of cns necrosis, head flatter; day 2: small head and eyes; day 5: small head and eyes, slightly underdeveloped gut | | | | |
hi2430 | 40S ribosomal protein S15 | day 1: pinched midbrain/hindbrain boundary, a bit of cns necrosis; day 2: a bit smaller head and eyes, round grey yolk with thin extension; day 5: small head and eyes, thin body, underdeveloped guts, round grey yolk | | | | |
hi2437 | 60S ribosomal protein L3 | day 1: slightly pinched midbrain/hindbrain boundary, a little cns necrosis; day 2: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped guts, sometimes a little pericardial edema | | | | |
hi2452 | RNA 3'-terminal phosphate cyclase-like protein | day 2: slightly smaller head and eye; day 5: small head and eyes, underdeveloped liver/gut, a little pericardial edema | | | | |
hi2453 | ATP-binding cassette, sub-family E , member 1 (RNAse L inhibitor) | day 2: slightly smaller head and eye; day 5: small head and eyes, underdeveloped liver/gut, a little pericardial edema | | | | |
hi2462 | clatherin, heavy chain | day 5: smaller and rounder head with thick jaw, a bit of pericardial edema, variably swollen yolk, underdeveloped liver/gut, sometimes slightly necrotic body | | | | |
hi2470 | eukaryotic translation initiation factor 3, subunit 6 | day 2: slightly smaller head and eye; day 5: very small head and eyes, pericardial edema with grey swollen yolk, underdeveloped liver/gut, sometimes slightly necrotic body | | | | |
hi2473 | mortalin-2 | day 3: slightly smaller head and eys; day 5: small head and eyes, a bit of pericardial edema with grey swollen yolk, underdeveloped liver/gut | | | | |
hi2479 | wee1a | d1: arrest during epiboly, never really becomes fish-shaped | | | | |
hi2487 | TFIIIA | day 3: slightly smaller head and eys; day 5: slightly small head and eyes, slightly underdeveloped gut | | | | |
hi2491 | TAF II 150 | day 4: smaller head and eyes, a bit of pericardial edema; day 5: small head and eyes, pericardial edema with grey swollen yolk, underdeveloped liver/gut, sometimes necrosis in body | | | | |
hi2499a | vacuolar sorting protein 18 | day 2: no/less body pigment; day 5: less body pigment (melanophores and iridophores), slightly underdeveloped gut | | | | |
hi2529 | RAD21 homolog | day 1: cns necrosis; day 2 worse necrosis; day 5: quite necrotic, very small head and eyes, pericardial edema, thin and degrading body, sometimes dead | | | | |
hi2557 | laminin C1 | day 1: short body with wavy notochord and slightly flat head, brain folds are irregular; day 2: really sick looking, very short body, head a bit swollen, a little pericardial edema; day 5: often dead, otherwise, almost no trunk, small eyes, reduced jaw, pericardial edema which may also be over head (note hi1193, hi3890, hi4131 all less severe, are short and bent dorsally, but overall healthier) | | | | |
hi2561 | b-myb | day 1: cns necrosis; day 2 worse necrosis (probably dead by day 5) | | | | |
hi2573a | novel (twistnb-like) | day 1: cns necrosis; day 2: small head and eyes, bubble brain, round yolk with thin extension; day 3 small head and eyes, round grey yolk, thin body, often bent down; day 5: small head and eyes, swollen unconsumed yolk, some pc edema, thin body & underdeveloped guts | | | | |
hi2578 | Nop10 | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped liver/gut, pericardial edema | | | | |
hi2581 | fibrillarin | day 1: pinched midbrain/hindbrain boundary, a little cns necrosis; day 2: small head and eyes, inflated hindbrain ventricle, thin body, rounder yolk with thin externsion; day 5: small head and eyes, thin body, underdeveloped liver/gut, round grey yolk | | | | |
hi2586 | lysyl-tRNA synthetase | day 3: slightly smaller head and eyes; day 5: small head and eyes, a little pericardial edema, underdeveloped liver/gut, sometimes some degeneration in body | | | | |
hi2596 | eukaryotic translation initiation factor 4A | day 2: slightly smaller head and eye, rounder yolk with thin extension, slightly thinner body; day 3: small head and eye, round grey yolk; day 5: very small head and eyes, pericardial edema, round grey yolk, underdeveloped liver/gut, sometimes slightly necrotic body | | | | |
hi2618 | Replication Protein A 70kd subunit | day 1: cns necrosis, flat head; day 2 very bad necrosis (probably dead by day 5) | | | | |
hi2635 | RNA polymerase II subunit B | day 1: cns necrosis, flat head; day 2 very bad necrosis; usually dead by day 5 | | | | |
hi2639a | TAF1B/RNA polymerase I, B | day 3: slightly smaller head and eyes; day 5: narrow/pointy head, small eyes, underdeveloped liver/gut | | | | |
hi2639b | Sds3 (Suppressor of Defective Silencing 3) | day 5: smaller and rounder head, variably smaller eyes, underdeveloped gut, sometimes a little pericardial edema | | | | |
hi2648 | Fbox protein 5 | day 1: brain folds a bit unusual, ventricles not well inflated, a little cns necrosis, eyes misshapen (not closed ventrally); day 2: smaller, bumpy head, thinner and sometimes bent body with round yolk, thin extension; day 5: often dead, if not: much smaller head and eyes, thin, bent, degenerating body | | | | |
hi2649 | 40S ribosomal protein S15A | day 1: cns necrosis and inflated hindbrain ventricle; day 2: smaller head and eyes, inflated hindbrain ventricle, rounder yolk with thin externsion, ventrally bent trunk; often dea by day 5, if not: very small head and eyes, thin and possibly curled and/or degrading body | | | | |
hi2653 | myosin-binding subunit of myosin phosphatase | d1: flat head (underinflated brain ventricles); d2: slightly smaller and bumpy head with irregular brain folds, preicardial edema, sometimes with pooling blood, trunk/tail sometimes wavy and/or necrotic d3-5: progressive necrosis in the body, often dead by day 5, if not: necrotic, bloated, edema (pericardial and over yolk and/or head) | | | | |
hi2666 | Cleavage and polyadenylation specificity factor 3 | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped liver/gut, pericardial edema | | | | |
hi2667 | novel (FLJ10290-like) | day 1: cns necrosis, flat head; day 2 very bad necrosis (probably dead by day 5) | | | | |
hi2675 | Cleavage and polyadenylation specificity factor 1 | day 4-5: small head and eyes , a little pericardial edema, underdeveloped liver/gut, sometimes bent and/or thin/necrotic body or tail | | | | |
hi2688 | multifunctional protein ADE2 | day 3: slightly smaller head and eyes, spotty pigment in eyes; day 5: slightly narrow head, eye pigment speckled, no xanthophores, sometimes inflate swim bladder | | | | |