"Angiogenesis "

     Angiogenesis, the growth of new capillary blood vessels from pre-existing ones is critical for several physiological processes (development, growth) as well of pathological ones (e.g., tumor growth). Endogenous proangiogenic and antiangiogenic factors have been identified in the past three decades, and currently constitute the basis for multiple therapeutic approaches design to control tumor growth and other angiogenesis-dependent diseases including macula degeneration and vascular malformations