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IAP 2004 Subjects

Health Sciences & Technology

HST.021/HST.020
Musculoskeletal Pathophysiology
Dwight R.Robinson
Mon, Wed, Fri, Jan 5, 7, 9, 12, 14, 16, 21, 23, 26, 28, 30, 09-11:30am, HAR-MED MEC 209

Pre-register on WebSIS and attend first class.
No listeners
Prereq:
Level: H 6 units Standard A - F Grading   

Growth and development of normal bone and joints, the process of mineralization, the biophysics of bone and response to stress and fracture, calcium and phosphate homeostasis and regulation by parathyroid hormone and vitamin D, and the pathogenesis of metabolic bone diseases and disease of connective tissue, joints, and muscles, with consideration of possible mechanisms and underlying metabolic derangements. (Only HST students may register under HST.020, graded P/D/F.) Enrollment is limited and only open to medical and graduate students. Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu

HST.146/HST.147
Human Biochemistry and Metabolic Diseases
John A Badwey
Tue, Thu, Jan 6, 8, 13, 15, 20, 22, 27, 29, 08:30am-12:30pm, HAR MED- MEC 209

Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Graded P/D/F   

First-year graduate level intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism and structures of key intermediates and enzymes important in human disease. Subject is divided into four areas: carbohydrates, lipids, amino acids and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations. (Only HST students may register under HST.146, graded P/D/F.) Enrollment limited.
Note:HST.146/147 is a units-to-be arranged subject, usually 6 units.
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu

HST.147/HST.146
Human Biochemistry and Metabolic Diseases
John A Badwey
Tue, Thu, Jan 6, 8, 13, 15, 20, 22, 27, 29, 08:30am-12:30pm, HAR MED-MEC 209

Pre-register on WebSIS and attend first class.
Prereq: Permission of instructor
Level: H 6 units Standard A - F Grading   

First-year graduate level intensive subject in human biochemistry and physiological chemistry that focuses on intermediary metabolism and structures of key intermediates and enzymes important in human disease. Subject is divided into four areas: carbohydrates, lipids, amino acids and nucleic acids. The importance of these areas is underscored with examples from diseases and clinical correlations. (Only HST students may register under HST.146, graded P/D/F.) Enrollment limited. Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu

HST.181/HST.180
Genetics in Medicine
David Harris
Tue, Thu, Jan 6, 8, 13, 15, 20, 22, 27, 29, 01-03:00pm, 66-160

Pre-register on WebSIS and attend first class.
No listeners
Prereq: 7.012 or 7.013 or 7.014, 7.05
Level: H 6 units Standard A - F Grading   

Introduction to basic concepts of medical genetics, with emphasis on patterns of genetic transmission, cellular and molecular basis of genetic disorders, and population genetics. In-depth consideration of both rare and more common genetic disorders, including single gene disorders (e.g. albinism, thalassemia, muscular dystrophy), chromosomal disorders (e.g. Down syndrome), cancer predisposition syndromes (e.g. neurofibromatosis), and the genetic contribution to common disorders (e.g. hemochromatosis). Includes patient presentations, consideration of genetic counseling issues, and the likely clinical impact of new genetic diagnostic techniques. (Only HST students may register under HST.180, graded P/D/F.)
Enrollment limited to medical and graduate students
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu

HST.191/HST.190
Statistical Planning and Analysis of Biomedical Investigations
Dianne Finkelstein
Mon, Wed, Fri, Jan 5, 7, 9, 12, 14, 16, 21, 23, 26, 28, 30, 01:30-03:30pm, HAR MED--MEC 209

Pre-register on WebSIS and attend first class.
No listeners
Prereq: 18.02
Level: H 6 units Standard A - F Grading   

Introduces statistical logic and technique as a basis for clinical decisions and scientific inference. Students learn to perform elementary statistical calculations, use a statistics computer program (STATA), and acquire the concepts and vocabulary to read biomedical literature critically and communicate productively with statistical professionals. Includes probability theory, normal sampling, chi-square and t-tests, analysis of variance, linear regression, and survival analysis. Case studies include applications to diagnostic screening, clinical drug trials, and physiological experiments. Emphasis on experimental studies rather than epidemiology. (Only HST students may register under HST.190, graded P/D/F.) Enrollment is limited and is only open to medical and graduate students. Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu

HST.505
Laboratory in Molecular and Cellular Sciences
Jeffrey R Morgan
Mon-Fri, Jan 5-9, 12-13, 23, 09am-05:30pm, MGH, 16th St., Charlestown

Pre-register on WebSIS and attend first class.
No listeners
Prereq: Biochemistry or cell biology
Level: H 12 units Standard A - F Grading   

Subject provides hands-on laboratory training in state-of-the-art experimental approaches and techniques in molecular and cellular sciences. Lab training is reinforced with didactic lectures which stress the theory behind these methodologies. Topics covered include: mammalian cell culture; tissue engineering; DNA cloning; gene transfer and gene therapy; transgenic animals; protein purification and analysis; and microscopy. Emphasis on the quantitative aspects of these methodologies. Students learn how to incorporate these approaches into an interdisciplinary research strategy aimed at addressing important questions in biomedical research.
Also meets at Shriners Hospital (Boston) 9-5:30 on 1/14 to 1/16 and 9-11 on 1/20 and 9-4:30 on 1/23.
Contact: Jeffrey R. Morgan, E25-518, (401) 863-9879, Jeffrey_Morgan@brown.edu

HST.718
Anatomy of Speech and Hearing
Barbara C. Fullerton
Schedule: TBD
Selection by departmental lottery. Do not pre-register on WebSIS.
Limited to 8 participants.
No listeners
Prereq: 7.012 or 7.013 or 7.014, permission of instructor
Level: H 6 units Standard A - F Grading   

The anatomical structures of speech and hearing. Gross anatomy of the head and neck, cranial nerves, and the central nervous system. Laboratory exercises provide experience in dissection and the analysis of microscopic specimens.
Only HST-students are allowed to enroll.
Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu

HST.935
Narrative Ethics: Literary Texts and Moral Issues in Medicine
Martha Montello
Tue, Thu, Jan 6, 8, 13, 15, 20, 22, 27, 29, 04-06:00pm, HAR MED--MEC 209

Pre-register on WebSIS and attend first class.
No listeners
Prereq:
Level: G 6 units Graded P/D/F   

The eight-session subject uses literary narratives and poetry to study ethical issues in medicine. Methodology emphasizes the importance of context, contingency, and circumstance in recognizing, evaluating, and resolving moral problems. Focus on developing the skills of critical and reflective reading that increase effectiveness in clinical medicine. Texts include short fiction and poetry by Woolf, Chekhov, Carver, Kafka, Hurston, Marquez, and Tolstoy. Instructor provides necessary philosophic and literary context followed by class discussion. Students keep a reading journal that examines the meanings of illness, the moral role of the physician, and the relevance of emotions, culture, faith, values, social realities, and life histories to patient care. Enrollment is limited and only open to medical and graduate students. Contact: Ron Smith, E25-518, 253-7470, ronsmith@mit.edu


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