Noteworthy Protein Knots

 Table of knotted proteins.

circa 2007

  The 52 knot of Ubiquitin Hydrolase (1xd3):

              

  Conjecture: the complex knot makes it difficult for proteosome to denature this protein

  Folding studies in the Jackson Lab.

Evolutionary origin of the 31 knot   1yh0  of X. campestris

Structures of Transcarbamylase from X. campestris with a trefoil knot and from Human without a knot

Simple mutation causes change in the enzyme's specificity

circa 2008

  The smallest knot: 31 in (2evf) with only 92 amino-acids

  

  The most complex knot: 61 in the dehalogenase (3bjx)

    

A Stevedore's Protein Knot (possible folding scenario)