Singapore-MIT Alliance for Research & Technology

BioSystems and Micromechanics (BioSyM) Inter-Disciplinary Research Group

  • BioSyM brings together a multidisciplinary team of faculties and researchers from MIT and the Universities and Research Institutes of Singapore. Our research deals with the development of new technologies to address critical medical and biological questions applicable to a variety of diseases. We aim to provide novel soultions to the healthcare industry and to the broader research infrastructure in Singapore.

  • The guiding tenet of BioSyM is that accelerated progress in biology and medicine will critically depend upon the development of modern analytical methods and tools that provide a deep understanding of the interactions between mechanics and biology at multiple length scales – from molecules to cells to tissues – that impact maintanance or disruption of human health.


BioSyM Highlights

Schematic of decellularized ECM study. MSCs are plated on TCPS and cultured to generate extracellular matrices. The MSCs are decellularized to expose the layer of ECM for proliferation studies with aMSCs.


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Upcoming Events

BioSyM Seminar Series 2014

Prof. Yong-Ak (Rafael) Song, Assistant Professor, New York University Abu Dhabi will present "New Microchip Technologies for Manipulation of Biomolecules and Ions in Bioengineering".

Date: 25th April 2014, Time: 3.30 pm, Venue: BioSyM, SMART Centre,
1 CREATE Way, Level 4, Enterprise Wing, Singapore 138602

7th World Congress of Biomechanics (WCB 2014), Boston, US, 6-11 July, 2014. (

Our people

Meet the Principal Investigators, Collaborators, researchers, students and staff of SMART-BioSyM

Our research

Read about our research thrusts/projects, lab facilities and publications