A filter function for univariate Cox regression.

Description

A function that performs Cox regression with bindings for surt, cens, and p is returned. This function filters genes according to the attained p-value from a Cox regression using surt as the survival times, and cens as the censoring indicator. It requires survival.

Usage

coxfilter(surt, cens, p)

Arguments

Value

Calls to the coxph function in the survival library are used to fit a Cox model. The filter function returns TRUE if the p-value in the fit is less than p.

Author(s)

R. Gentleman

See Also

Anova

Examples

   set.seed(-5)
   sfun <- coxfilter(rexp(10), ifelse(runif(10) < .7, 1, 0), .05)
   ffun <- filterfun(sfun)
   dat <- matrix(rnorm(1000), ncol=10)
   out <- genefilter(dat, ffun)