Function

1. Filaments in the cycloskeleton:

  • Actin, threadmilling
  • Microtubules, dynamic instability
  • Molecular motors, ratchet models, asymmetric hopping models

2. Protein-Nucleic acid composites:

  • Electrostatic interactions
  • Specific and non-specific binding of factors to DNA regulatory elements
  • Berg-von Hippel, wight matrices (profiles), information content

Thursday October 22
L12: (HP)  Rouse model

Tuesday  October 27
L13: (MK) Microtubules  

Thursday October 29
L14:   (MK) Molecular motors   

Tuesday November 3 
L15:  (LM)  Protein/DNA energetics

Thursday  November 5 
L16: (LM) Protein/DNA search

 

Thursday  November 19 
L20: (HP)  Molecular search: compact exploration

Tuesday November 24
L21: (HP) Inference : how cells sense the environment, Berg-Purcell


lec1- function