The control network group focuses on the development of fundamental theory and algorithms for the analysis and design of two different types of control networks: (a) ground transportation networks and (b) biomolecular networks in living cells.

News

New Device Could Make Large Biological Circuits Practical MIT News Office, November 2014

Costruito il Primo Circuito Biologico di Precisione ANSA, November 2014

Older News

Bulding a Smarter 'Smart Car' Discovery News, June 2011

Are we ready for driverless cars? by C. Gillis, Maclean's Canadian news magazine, November 2011

Enlightening the Load by L. Bryan Ray, Science, October 2011

Living cells say: Can you hear me now? by D. L. Chandler MIT News Office, November 2011

'Smart cars' that are actually, well, smart by E. Finn MIT News Office, June 2011

Modularity Defined by H. Sauro, Nature/EMBO Molecular Systems Biology 2008

Transportation Networks


Multi-agent Hybrid Systems Lab

The decreasing costs of embedded computing and communication technologies are pushing several of today’s engineering systems toward increased levels of autonomy. Highly interconnected networks of physical devices and embedded computers, exhibiting continuous (due to the physics) and discrete (due to the computation) behavior, that is, Cyber-Physical Systems (CPS), are becoming a substantial part of our life. A remarkable example is that of transportation networks. While the potential for improvement is enormous, increased levels of autonomy also bring about critical problems. Challenges include ensuring a correct and safe functioning despite the large number of physical devices, the intrinsically hybrid continuous/discrete nature of the system, limited information, and the presence of human operators. How can one design these systems so they are provably correct despite these challenges? How does one formally verify their behavior? Del Vecchio’s group is addressing these questions by using and developing tools and algorithms based on control theory, dynamical systems, optimization, and computer science. A major focus is on developing algorithmic procedures that can run fast in real-time and have reduced computational demands so they can be effectively used in real applications. At the same time, Del Vecchio's group works with human-factor experts to create hybrid dynamical models of human drivers, which are employed in the design phase, and perform test-bed and field experiments through collaboration with automotive companies.

Biomolecular Networks


Biomolecular Networks Lab

Modularity is the property that allows to predict the behavior of a complicated system from that of its components, guaranteeing that the properties of individual components do not change after interconnection. Researchers in the systems biology community have hypothesized that modularity may be a property of biological systems, proposing functional modules as a critical level of biological organization. This view has profound implications on evolution and also implies that biology, just like engineering, can be understood in a hierarchical fashion. However, modularity is still subject of intense debate and remains one of the most vexing questions in systems biology. At the same time, modularity is critical for the field of synthetic biology, in which researchers are pursuing a bottom-up approach to design. Del Vecchio's group addresses this question, by employing and extending the theory of nonlinear control systems, with the ultimate goal of establishing fundamental theory for modular biomolecular network analysis and design. This theory seeks to (a) shed light on the extent to which modularity is a principle of biological organization, (b) provide techniques to analyze networks modularly, and (c) empower synthetic biology of a number of concrete design tools to enforce modular composition, which will move the field forward.

RA position available contact ddv@mit.edu