| Family | Zebrafish Gene | Phenotypic Description | Image #1 | Image #2 | Image #3 | Image #4 |
| hi399 | NRF-1 | day 5: slightly smaller eyes (more details in Becker, et al., Development 125: 4369-4378 (1998)) |  | | | |
| hi409 | IFT81 / carnitine deficiency-associated, expressed in ventricle 1 | day 2: ventrally curved body, may see beginning of kidney cyst; day 5, ventrall curved trunk, kidney cyst |  |  |  | |
| hi428 | novel (AK000411) | day 4: some pericardial edema, a bit smaller/rounder head, grey yolk with underdev guts, disorganized muscle striations; day 5: also some necrosis in head, muscle look to be degenerating |  | | | |
| hi429 | novel (DJ434O14.5-like) | day 5: slightly smaller head and eyes, smaller liver, slightly underdeveloped gut |  | | | |
| hi447 | novel (denticless homolog) | day 1: cns necrosis, flat head, thin yolk extension; day 2 very bad necrosis; most dead by day 5 |  | | | |
| hi459 | novel (arf2-like) | day 2: ventrally curved body, may see beginning of kidney cyst; day 5, ventrall curved trunk, kidney cyst |  | | | |
| hi471 | MCM3-associated protein | day 2: a bit cns necrosis and smaller head and eye; day 5: small and necrotic head and eyes, underdevelopd liver/gut and often pericardial edema |  |  | | |
| hi472 | VIP36-like | day 5: sb- with slightly smaller head and eyes and very little movement/touch response (capable of spontaneous movements) |  | | | |
| hi486 | kinesin-related motor protein EG5 | day 1: small amount of cns necrosis; day 3: slightly smaller head and eyes; day 5 small head/eye, underdev guts, usually some pc edema, sometimes body bent dorsally or S-shaped |  | | | |
| hi491 | TCP-1 alpha | day 2: necrosis in eyes; day 4 and 5: small/necrotic head and eyes, percardial edema, grey yolk with underdeveloped liver/gut; often body necrotic by day 5 |  | | | |
| hi526a | mitochondial adp/atp translocator | day 5: slightly smaller head and eyes, slightly underdeveloed liver/gut |  | | | |
| hi526b | novel (FLJ31121-like) | day2: mild cns necrosis; day 3: small head and eyes; day 5: small head and eyes, variable pericardial edema, underdeveloped liver/gut |  |  | | |
| hi528 | cotamer zeta1 | day 3: less pigment in eye due to RPE degeneration, head and eyes a bit smaller; day 5: narrower head, more extensive RPE degeneration leads to smaller eyes with little pigment, underdeveloped liver/gut |  |  | | |
| hi548 | vHNF-1 | day 2: begin to see kidney cysts; day 4-5 kidney cyst, pericardial edema, underdeveloped liver/gut, slightly smaller head/eyes (alleles hi1843 and hi2169 may also have earlier visible midbrain/hindbrain boundary defects and only one or no otoliths; these are much sicker than hi548 days 3-5) (more details in Sun and Hopkins, Genes Dev. 15:3217-3229 (2001)) |  |  | | |
| hi550 | SNF2-related | day 2: cns necrosis; day 5: small head and eyes and underdeveloped liver/gut |  | | | |
| hi557 | novel (C7orf14-like) | d2: cns necrosis, small head and eyes, rounder yolk, day 5: small head and eyes, underdeveloped liver/gut, sometimes trunk bent dorsally; note: hi557 is a very mild allele, the other three alleles are more like this description. |  |  |  | |
| hi558 | valyl-tRNA synthetase | day 3: begin small head and eye, grey swollen yolk; day 5: small head and eye, underdeveloped liver/gut, pericardial edema |  | | | |
| hi559 | phosphatidylinositol synthase | day 5: smaller head and eyes, thick jaw, underdeveloped liver/gut |  | | | |
| hi572 | novel (FLJ20508-like) | day 5: slightly smaller and rounder head, slightly smaller eyes, posterior arches reduced or missing, slightly underdeveloped liver/gut |  | | | |
| hi577a | v-ATPase subunit e | day 2: little/no body pigment, day 3 spotty body pigment, small head, small otoliths, day 5: little no body pigment, small head, eyes, and ears, underdeveloped gut, thin body |  | | | |
| hi577b | 40S ribosomal protein S5 | day 2: a little cns necrosis, inflated hindbrain ventricle, rounder yolk with thin extension; day 5: small head and eyes, round unconsumed yolk, underdeveloped liver/gut, thin body |  | | | |
| hi591 | novel (ars2-like) | day 2: a little cns necrosis; day 3 cns necrosis more pronounced, head and eyes a bit smaller; day 4-5: small head and eye, thick jaw, pericardial edema, sometimes necrosis in body and embryo bent dorsally |  |  | | |
| hi601 | small nuclear ribonucleoprotein D1 | day 2: cns necrosis, hindbrain ventricle inflated, rounder yolk with thin extension; later days necrosis worsens through body, dead by day 5 |  | | | |
| hi642 | TCP-1 beta | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped liver/gut, pericardial edema; head and/or body sometimes necrotic |  | | | |
| hi688 | ribonucleoside reductase R2 | day 2: cns necrosis, hindbrain ventricle inflated, rounder yolk with thin extension; later days necrosis worsens through body, dead by day 5 |  | | | |
| hi781 | deltaA | day3-5 body bent dorsally (variable penetrance) |  |  | | |
| hi783 | DNA pol e subunit b | day 2: cns necrosis, smaller head and eye, hindbrain ventricle a bit inflated, rounder yolk with thin extension; later days necrosis worsens through head and body, dead by day 5 |  | | | |
| hi800a | TCP-1 eta | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped liver/gut, pericardial edema |  | | | |
| hi821a | novel (KIAA0007-like) | day 1: a little cns necrosis; day 2: cns necrosis, rounder yolk; later days necrosis worsens through head and body, dead by day 5 (note: hi2144 allele is far less severe; necrosis is far less visible; small head and eyes at day 5) |  | | | |
| hi823 | 60S ribosomal protein L14 | day 1 (late): pinched midbrain/hindbrain boundary, slightly inflated hindbrain ventricle; day 2: cns necrosis, smaller head and eye, slightly inflated hindbrain ventricle, rounder yolk with thin extension; day 3 small head and eyes, thin body, round grey yolk with thin extension, a bit of pericardial edema; days 4-5 - increasingly sicker/necrotic, edema worsens, some dead by day 5 |  |  |  | |
| hi887 | translocase of inner mitochondrial membrane 23 | day 3: slightly smaller head and eyes, rounder grey yolk; day 5: small head and eyes, underdeveloped liver/gut, pericardial edema |  | | | |
| hi889 | TAF55 | day 5: slightly smaller head and eyes, slightly underdeveloped liver/gut |  | | | |
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