Family | Zebrafish Gene | Phenotypic Description | Image #1 | Image #2 | Image #3 | Image #4 |
hi891 | spinster homolog | day 2: very dark/rotting yolk with thin or no extension; day 5: thin, necrotic, big edema, dead or dying | | | | |
hi904 | mindbomb (E3 ubiquitin ligase) | day 1: brain folds are irregular, forebrain too large; day 2: brain and neural tube disorganized - cells too round and loosely packed, bit smaller eyes, bumpy head, a bit of pc edema, round yolk; day 5: body curled dorsally, tiny eyes, small head with thick jaw. | | | | |
hi923 | v-ATPase SDF/54kD subunit | day 2: no/less body pigment; day 5: less body pigment, small head and eyes, underdeveloped liver/gut, sometimes some pericardial edema | | | | |
hi929 | eukaryotic translation initiation factor 2 gamma | day 2: cns necrosis, rounder yolk; later days necrosis worsens through head and body, dead by day 5 | | | | |
hi932 | novel (BAP28-like) | day 1: a bit of cns necrosis (head appears a bit flat and grainy); day 2: a bit smaller head and eyes, round grey yolk with thin extension; day 5: small head and eyes, a bit thinner body, underdeveloped liver/guts, sometimes a bit of pericardial edema | | | | |
hi933 | pbx4 | day 2: sometimes a little pericardial edema, denting into yolk, no fin buds; day 3, slightly smaller head and eyes, no pectoral fins; day 5: a small head and eyes, a bit of pericardial edema, no pectoral fins | | | | |
hi954 | UDP-glucuronic acid decarboxylase | day 5: a bit rounder/smaller head; cartialge stains very poorly with Alcian blue | | | | |
hi962 | nuclear transcription factor Y, gamma | day 4-5: smaller head and eyes, underdeveloped liver/gut, some unconsumed yolk, a little pericardial edema | | | | |
hi975 | ndr1/squint | day 1: variable penetrance, variable severity of cyclopia; day 5: still alive and normal body size,but usually fail to hatch from chorion, variably narrow head with eyes closer together or slightly fused | | | | |
hi994 | novel (FLJ22611-like) | day 4-5: smaller head and eyes, underdeveloped liver/gut, some unconsumed yolk, a little pericardial edema | | | | |
hi998 | RNA polymerase II CTD phosphatase | day 5: smaller narrow/pointy head, smaller eyes, underdeveloped liver/gut | | | | |
hi1002 | casein kinase I alpha | day 3: stubby pectoral fins, day 5: a bit smaller head/jaw, stubby pectoral fins; Alcian blue staining reveals cartilages rough edged and shortened, especially Meckel's cartilage | | | | |
hi1011 | Opa-interacting protein 2 (3' exoribonuclease family) | day 3: slightly smaller head and eyes; day 5: small head and eyes, underdeveloped guts, sometimes pericardial edema | | | | |
hi1016 | 60S ribosomal protein L13 | day 1: pinched midbrain/hindbrain boundary, a bit of cns necrosis; day 2: a bit smaller head and eyes, hindbrain ventricle slightly inflated, round grey yolk with thin extension; day 5: small head and eyes, underdeveloped liver/gut, a bit of pericardial edema, sometimes trunk bent dorsally | | | | |
hi1019 | AD24 | day 1: transient cns necrosis; day 3: small head and eyes, rounder grey yolk; day 5: small head and eyes, slightly thinner body, underdeveloped liver/gut, pericardial edema, some unconsumed yolk | | | | |
hi1026 | 40S ribosomal protein S18 | day 2: small head and eyes, inflated hindbrain, rounder yolk with thin extension; day 5: small head and eyes, underdeveloped liver/gut, a bit of pericardial edema | | | | |
hi1034a | novel (G10) | day 1: cns necrosis, flat head; day 2 very bad necrosis; embryos become increasingly necrotic and die day 3-5 | | | | |
hi1034b | 40S ribosomal protein S7 | day 1: pinched midbrain/hindbrain boundary, a little cns necrosis; day 2: somewhat smaller head and eyes, round grey yolk with thin extension; day 5: small head and eyes, thin body, round grey yolk, underdeveloped liver/gut, pericardial edema | | | | |
hi1045 | aurora-related ser/thr kinase | day 1: cns necrosis, flat head; day 2 very bad necrosis; embryos become increasingly necrotic and die day 3-5 | | | | |
hi1055a | MAK16-like | day 2: small head and eyes, a little cns necrosis, round yolk with thin extension; day 3: very small head and eyes, round grey yolk, thin body; d5: very small head and eyes, round grey yolk, thin body, sometimes bent verntrally, pericardial edema, underdeveloped liver/gut | | | | |
hi1055b | pontin/TIP49 | day 2: a little cns necrosis, body bent ventrally, sometimes kidney cyst already visible; days 3-4, head necrosis/shrinkage gets worse, pericardial edema develops, body stays ventrally curved, kidney cyst develops; day 5: necrosis begins to spread throughout embryo | | | | |
hi1058 | sec61 homolog | day 3-4: small head and eyes, body may curve dorsally, pericardial edema may develop; day 5: small head and eye, some anterior arch structures reduced, underdeveloped liver/guts, pericardial edema, body often bent dorsally | | | | |
hi1059 | neurogenin-1 | day 5: mouth agape, very little motility or touch response | | | | |
hi1061 | 60S ribosomal protein L7 | day 1: a bit of cns necrosis; day 2: a bit smaller head and eyes, hindbrain ventricle inflated a bit, round grey yolk with thin extension; day 5: small head and eyes, thin body, underdeveloped liver/gut, a bit of pericardial edema, sometimes trunk bent dorsally | | | | |
hi1072 | baf53a (swi/snf complex component) | day 2-3: cns necrosis, slightly smaller head and eyes, a little pericardial edema; day 5: small head and eyes, underdeveloped liver/gut, pericardial edema which can expand to cover yolk and head, often very necrotic overall | | | | |
hi1073 | novel (KIAA0877-like) | day 2: body curved ventrally. By day 5, the curvature can be vental or lateral or somewhere inbetween | | | | |
hi1086a | DEAD box polypeptide 27 | day 2: small head and eyes, slightly inflated hindbrain ventricle, round yolk with thin extension; days 3-4: small head/eyes, round grey yolk with thin extension, body a little shorter and thinner; day 5: small head/eyes, pericardial edema, thin and short body, underdeveloped liver/gut | | | | |
hi1113a | chromosome adhesion protein SMC1-like | day 2: cns necrosis, rounder dark yolk, body may be bent dorsally; later days necrosis worsens through head and body, dead or very necrotic by day 5 | | | | |
hi1113b | laminin B1 | day 1: short body with thin and wavy notochord and blocky head; day 2: really short body; day 5: body short and bent dorsally, head a bit small | | | | |
hi1116a | novel (DT1P1A10-like) | day 5: thinner/pointy head, small eyes, a bit of pericardial edema, underdeveloped liver/gut | | | | |
hi1116b | eukaryotic translation elongation factor 1 alpha | day 3: small head and eyes, rounder yolk; increasingly necrotic day 5 | | | | |
hi1124 | RNA polymerase I 140 kDa subunit | day 3: slightly smaller head and eyes; day 5: thinner/pointy head, small eyes, a bit of pericardial edema, underdeveloped liver/gut | | | | |