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| LentiLox 3.7 (pLL3.7) | ||||||||
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| LentiLox 3.7 is a lentiviral vector designed for inducing RNA interference in a wide range of cell types, tissues and organisms. We have use this vector to infect and efficiently silence proteins in hematopoetic stem cells and their progeny, and have used infected embryonic stem cells and single cell embryos to create transgenic animals (Rubinson and Dillon et al, Nature Genetics, 2003). Note: Lentiviral vectors have signficant biosafety issues, explained here. | ||||||||
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| Restriction Map | ||||||||
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| Sequence | ||||||||
| LentiLox 3.7 has been fully sequenced. The sequence
can be downloaded in Genebank format or text format, as well as viewed as
text in the browser. |
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| MTA - Licencing issues for plasmid requests | ||||||||
| Academic labs can obtain this reagent through ATCC. To order, one should call 1-800-638-6597 and request item VRMC-39. Item: VRMC-39 Industry or biotech laboratories who wish to use this vector must obtain a license throught MIT's Technology Licensing Office: http://web.mit.edu/tlo/www/ Note: This vector must be used in conjuction with packaging vectors which are commercially available through Invitrogen (Vira Power Lentiviral Support Kit K4970-00). . |
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| This Webpage was created by Chris Dillon (updated by AED) | ||||||||
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