2007~ present

Vitu E*, Kim S*, Sevier CS, Lutzky O, Heldman N, Bentzur M, Unger T, Yona M, Kaiser CA, Fass D.

  Oxidative activity of yeast Ero1p on protein disulfide isomerase and related oxidoreductases of the endoplasmic reticulum.

J Biol Chem. 2010 Mar 26. [Epub ahead of print]


Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C.

  The genetic landscape of a cell.

Science. 2010 Jan 22;327(5964):425-31.

Vitu E, Gross E, Greenblatt HM, Sevier CS, Kaiser CA, Fass D.
  Yeast Mpd1p reveals the structural diversity of the protein disulfide isomerase family
J Mol Biol
. 2008 Dec 19;384(3):631-40. Epub 2008 Sep 27.

Risinger AL, Kaiser CA.
 Different Ubiquitin Signals Act at the Golgi and Plasma Membrane to Direct GAP1Trafficking.
Mol Biol Cell. 2008 Apr 23. [Epub ahead of print]
PMID: 18434603 [PubMed - as supplied by publisher]

Sevier CS, Kaiser CA.
 Ero1 and redox homeostasis in the endoplasmic reticulum.
Biochim Biophys Acta. 2007 Dec 23; [Epub ahead of print]
PMID: 18191641 [PubMed - as supplied by publisher]

Sevier CS, Qu H, Heldman N, Gross E, Fass D, Kaiser CA.
 Modulation of cellular disulfide-bond formation and the ER redox environment by feedback regulation of Ero1. Cell. 2007 Apr 20;129(2):333-44.
PMID: 17448992 [PubMed - indexed for MEDLINE]

2001~ 2006
:1: Vitu E, Bentzur M, Lisowsky T, Kaiser CA, Fass D.
 Gain of function in an ERV/ALR sulfhydryl oxidase by molecular engineering of the shuttle disulfide.
J Mol Biol. 2006 Sep 8;362(1):89-101. Epub 2006 Aug 8.
PMID: 16893552 [PubMed - indexed for MEDLINE]

2: Risinger AL, Cain NE, Chen EJ, Kaiser CA.
 Activity-dependent reversible inactivation of the general amino acid permease.
Mol Biol Cell. 2006 Oct;17(10):4411-9. Epub 2006 Aug 2.
PMID: 16885415 [PubMed - indexed for MEDLINE]

3: Sevier CS, Kaiser CA.
 Conservation and diversity of the cellular disulfide bond formation pathways.
Antioxid Redox Signal. 2006 May-Jun;8(5-6):797-811. Review.
PMID: 16771671 [PubMed - indexed for MEDLINE]

4: Gao M, Kaiser CA.
 A conserved GTPase-containing complex is required for intracellular sorting ofthe general amino-acid permease in yeast.
Nat Cell Biol. 2006 Jul;8(7):657-67. Epub 2006 May 28.
PMID: 16732272 [PubMed - indexed for MEDLINE]

5: Rubio-Texeira M, Kaiser CA.
 Amino acids regulate retrieval of the yeast general amino acid permease from the vacuolar targeting pathway.
Mol Biol Cell. 2006 Jul;17(7):3031-50. Epub 2006 Apr 26.
PMID: 16641373 [PubMed - indexed for MEDLINE]

6: Sevier CS, Kaiser CA.
 Disulfide transfer between two conserved cysteine pairs imparts selectivity to protein oxidation by Ero1.
Mol Biol Cell. 2006 May;17(5):2256-66. Epub 2006 Feb 22.
PMID: 16495342 [PubMed - indexed for MEDLINE]

7: Gross E, Sevier CS, Heldman N, Vitu E, Bentzur M, Kaiser CA, Thorpe C, Fass D.
 Generating disulfides enzymatically: reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p.
Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):299-304. Epub 2006 Jan 3.
PMID: 16407158 [PubMed - indexed for MEDLINE]

8: Vala A, Sevier CS, Kaiser CA.
 Structural determinants of substrate access to the disulfide oxidase Erv2p.
J Mol Biol. 2005 Dec 9;354(4):952-66. Epub 2005 Oct 10.
PMID: 16288914 [PubMed - indexed for MEDLINE]

9: Sevier CS, Kadokura H, Tam VC, Beckwith J, Fass D, Kaiser CA.
 The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases.
Protein Sci. 2005 Jun;14(6):1630-42.
PMID: 15930008 [PubMed - indexed for MEDLINE]

10: Gross E, Kastner DB, Kaiser CA, Fass D.
 Structure of Ero1p, source of disulfide bonds for oxidative protein folding in the cell.
Cell. 2004 May 28;117(5):601-10.
PMID: 15163408 [PubMed - indexed for MEDLINE]

11: Chen EJ, Kaiser CA.
 LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway.
J Cell Biol. 2003 Apr 28;161(2):333-47.
PMID: 12719473 [PubMed - indexed for MEDLINE]

12: Chen EJ, Kaiser CA.
 Amino acids regulate the intracellular trafficking of the general amino acid permease of Saccharomycescerevisiae.
Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14837-42. Epub 2002 Nov 4.
PMID: 12417748 [PubMed - indexed for MEDLINE]

13: Sevier CS, Kaiser CA.
 Formation and transfer of disulphide bonds in living cells.
Nat Rev Mol Cell Biol. 2002 Nov;3(11):836-47. Review.
PMID: 12415301 [PubMed - indexed for MEDLINE]

14: Magasanik B, Kaiser CA.
 Nitrogen regulation in Saccharomyces cerevisiae.
Gene. 2002 May 15;290(1-2):1-18. Review.
PMID: 12062797 [PubMed - indexed for MEDLINE]

15: Ram RJ, Li B, Kaiser CA.
 Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p.
Mol Biol Cell. 2002 May;13(5):1484-500.
PMID: 12006647 [PubMed - indexed for MEDLINE]

16: Gross E, Sevier CS, Vala A, Kaiser CA, Fass D.
 A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p.
Nat Struct Biol. 2002 Jan;9(1):61-7.
PMID: 11740506 [PubMed - indexed for MEDLINE]

17: Sevier CS, Cuozzo JW, Vala A, Aslund F, Kaiser CA.
 A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation.
Nat Cell Biol. 2001 Oct;3(10):874-82.
PMID: 11584268 [PubMed - indexed for MEDLINE]

18: Helliwell SB, Losko S, Kaiser CA.
 Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease.
J Cell Biol. 2001 May 14;153(4):649-62.
PMID: 11352928 [PubMed - indexed for MEDLINE]
1992~ 2000
1: Frand AR, Kaiser CA.
 Two pairs of conserved cysteines are required for the oxidative activity of Ero1p in protein disulfide bond formation in the endoplasmic reticulum.
Mol Biol Cell. 2000 Sep;11(9):2833-43.
PMID: 10982384 [PubMed - indexed for MEDLINE]

2: Payne WE, Kaiser CA, Bevis BJ, Soderholm J, Fu D, Sears IB, Glick BS.
 Isolation of Pichia pastoris genes involved in ER-to-Golgi transport.
Yeast. 2000 Aug;16(11):979-93.
PMID: 10923020 [PubMed - indexed for MEDLINE]

3: Frand AR, Cuozzo JW, Kaiser CA.
 Pathways for protein disulphide bond formation.
Trends Cell Biol. 2000 May;10(5):203-10. Review.
PMID: 10754564 [PubMed - indexed for MEDLINE]

4: Kurihara T, Hamamoto S, Gimeno RE, Kaiser CA, Schekman R, Yoshihisa T.
 Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae.
Mol Biol Cell. 2000 Mar;11(3):983-98.
PMID: 10712514 [PubMed - indexed for MEDLINE]

5: Cuozzo JW, Kaiser CA.
 Competition between glutathione and protein thiols for disulphide-bond formation.
Nat Cell Biol. 1999 Jul;1(3):130-5.
PMID: 10559898 [PubMed - indexed for MEDLINE]

6: Frand AR, Kaiser CA.
 Ero1p oxidizes protein disulfide isomerase in a pathway for disulfide bond formation in the endoplasmic reticulum.
Mol Cell. 1999 Oct;4(4):469-77.
PMID: 10549279 [PubMed - indexed for MEDLINE]

7: Roberg KJ, Crotwell M, Espenshade P, Gimeno R, Kaiser CA.
 LST1 is a SEC24 homologue used for selective export of the plasma membrane ATPase from the endoplasmic reticulum.
J Cell Biol. 1999 May 17;145(4):659-72.
PMID: 10330397 [PubMed - indexed for MEDLINE]

8: Chen EJ, Frand AR, Chitouras E, Kaiser CA.
 A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1.
Mol Cell Biol. 1998 Dec;18(12):7139-46.
PMID: 9819400 [PubMed - indexed for MEDLINE]

9: Frand AR, Kaiser CA.
 The ERO1 gene of yeast is required for oxidation of protein dithiols in the endoplasmic reticulum.
Mol Cell. 1998 Jan;1(2):161-70.
PMID: 9659913 [PubMed - indexed for MEDLINE]

10: Roberg KJ, Bickel S, Rowley N, Kaiser CA.
 Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8.
Genetics. 1997 Dec;147(4):1569-84.
PMID: 9409822 [PubMed - indexed for MEDLINE]

11: Shaywitz DA, Espenshade PJ, Gimeno RE, Kaiser CA.
 COPII subunit interactions in the assembly of the vesicle coat.
J Biol Chem. 1997 Oct 10;272(41):25413-6.
PMID: 9325247 [PubMed - indexed for MEDLINE]

12: Roberg KJ, Rowley N, Kaiser CA.
 Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae.
J Cell Biol. 1997 Jun 30;137(7):1469-82.
PMID: 9199164 [PubMed - indexed for MEDLINE]

13: Gimeno RE, Espenshade P, Kaiser CA.
 COPII coat subunit interactions: Sec24p and Sec23p bind to adjacent regions of Sec16p.
Mol Biol Cell. 1996 Nov;7(11):1815-23.
PMID: 8930902 [PubMed - indexed for MEDLINE]

14: Hong E, Davidson AR, Kaiser CA.
 A pathway for targeting soluble misfolded proteins to the yeast vacuole.
J Cell Biol. 1996 Nov;135(3):623-33.
PMID: 8909538 [PubMed - indexed for MEDLINE]

15: Elrod-Erickson MJ, Kaiser CA.
 Genes that control the fidelity of endoplasmic reticulum to Golgi transport identified as suppressors of vesicle budding mutations.
Mol Biol Cell. 1996 Jul;7(7):1043-58.
PMID: 8862519 [PubMed - indexed for MEDLINE]

16: Gimeno RE, Espenshade P, Kaiser CA.
 SED4 encodes a yeast endoplasmic reticulum protein that binds Sec16p and participates in vesicle formation.
J Cell Biol. 1995 Oct;131(2):325-38.
PMID: 7593162 [PubMed - indexed for MEDLINE]

17: Espenshade P, Gimeno RE, Holzmacher E, Teung P, Kaiser CA.
 Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.
J Cell Biol. 1995 Oct;131(2):311-24.
PMID: 7593161 [PubMed - indexed for MEDLINE]

18: Payne WE, Gannon PM, Kaiser CA.
 An inducible acid phosphatase from the yeast Pichia pastoris: characterization of the gene and its product.
Gene. 1995 Sep 22;163(1):19-26.
PMID: 7557473 [PubMed - indexed for MEDLINE]

19: Shaywitz DA, Orci L, Ravazzola M, Swaroop A, Kaiser CA.
 Human SEC13Rp functions in yeast and is located on transport vesicles budding from the endoplasmic reticulum.
J Cell Biol. 1995 Mar;128(5):769-77.
PMID: 7876304 [PubMed - indexed for MEDLINE]

20: Pryer NK, Salama NR, Schekman R, Kaiser CA.
 Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.
J Cell Biol. 1993 Feb;120(4):865-75.
PMID: 8432727 [PubMed - indexed for MEDLINE]

21: Griff IC, Schekman R, Rothman JE, Kaiser CA.
 The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein.
J Biol Chem. 1992 Jun 15;267(17):12106-15.
PMID: 1601878 [PubMed - indexed for MEDLINE]

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