| People |
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| MIT only |
Selected recent publications.
Contact Ms.Marcia Ross for reprints
or preprints: mross@mit.edu.
2013 | 2012 | 2011 | 2010
2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000
1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990
1989 | 1988 | 1987 | 1986 | 1985 | 1984 | 1983 | 1982 | 1981 | 1980
1979 | 1978 | 1977 | 1976 | 1975 | 1974 | 1973 | 1972 | 1971
2013
Seneviratne UI, Godoy LC, Wishnok JS, Wogan GN, Tannenbaum SR. 2013. Mechanism-based triarylphosphine-ester probes for capture of endogenous RSNOs.
J Amer Chem Soc; epub April 24. PMID: 23614769
Prestwich E, Mangerich A, Pang B, McFaline JL, Lonkar P, Sullivan MR, Trudel LJ, Taghizadeh K, Dedon PC. 2013. Increased levels of inosine in a mouse model of inflammation. Chem ResToxicol. Mar 18. [Epub ahead of print] PMID: 23506120
Edrissi B, Taghizadeh K, Dedon PC. 2013. Quantitative analysis of histone modifications: formaldehyde is a source of pathological N(6)-formyllysine that is refractory to histone deacetylases. PLoS Genet. 9: e1003328. PMCID: PMC3585032
Tripathi DN, Chowdhury R, Trudel LJ, Tee AR, Walker CL, and Wogan GN. 2013. Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1. Proc Nat Acad Sci USA, in press.
Nguyen DD, Eston MA, Muthupalani S, Mobley M, Potter A, Snapper S.B, Fox JG. 2013. Colitis and Colon Cancer in WASP-deficient Mice Require Helicobacter Spp. Inflam Bowel Dis, in press.
Knutson CG, Mangerich A, Zeng Y, Raczynski AR, Liberman RG, Kang P, Ye W, Prestwich E, Lu K, Wishnok JS, Korzenik JR, Wogan GN, Fox JG, Dedon PC, Tannenbaum SR. 2013. Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease. Proc Natl Acad Sci USA, in press.
Li D, Fedeles BI, Shrivastav N, Delaney JC, Yang X, Wong C, Drennan CL, Essigmann JM. 2013. Removal of alkylation DNA adducts from N2-alkylguanine and N4-alkylcytosine by the adaptive response protein AlkB. Chem. Res. Toxicol. [Accepted for publication pending minor revision]
2012
Cui L, Ye W, Prestwich E, Wishnok JS, Taghizadeh K, Dedon PC, Tannenbaum SR. 2012. Comparative analysis of four oxidized guanine lesions from reactions of DNA with peroxynitrite, singlet oxygen and γ-radiation. Chem Res Toxicol 26:195-202. PMCID: PMC3578445
Godoy LC, Anderson CT, Chowdhury R, Trudel LJ,Wogan GN. 2012. Endogenously produced nitric oxide mitigates sensitivity of melanoma cells to cisplatin. Proc. Nat. Acad. Sci. USA, 109(50): 20373-20378. PMCID: PMC3528548 [Available on 2013/6/11]
Lim, K-S, Liang C, Taghizadeh K, Wishnok JS, Chan W, DeMott MS, Babu IR, Tannenbaum SR, Dedon PC. 2012. In situ analysis of 8-oxo-7,8-dihydro-2’-deoxyguanosine oxidation reveals sequence- and agent-specific damage spectra. J Am Chem Soc 134:18053-18064. PMCID: PMC3503518
Muthupalani S, Ge Z, Feng Y, Rickman B, Mobley MW, Van Rooijen N, and Fox JG. 2012. Systemic macrophage depletion inhibits Helicobacter bilis induced proinflammatory cytokine mediated typhlocolitis and impairs bacterial colonization dynamics in a –Balb/c Rag2-/- mouse model of IBD. Infection and Immunity 80(12):4388-97. PMCID: PMC3497414 [Available on 2013/6/1]
Wogan GN, Dedon PC, Tannenbaum SR, Fox JG. 2012. Infection, inflammation and colon carcinogenesis. Oncotarget; 3(8):737-738. PMCID: PMC3478450
Sohn JJ, Schetter, AJ, Yfantis HG, Ridnour LA, Horikawa I, Khan MA, Robles AI, Hussain SP, Goto A, Bowman ED, Hofseth LJ, Bartkova J, Bartek J, Wogan GN, Wink DA, Harris CC. 2012. Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease. PLoS One, 7(9): e44156. PMCID: PMC3435404
Chowdhury R, Godoy LC, Thiantanawat A, Trudel LJ, Deen WM, and Wogan GN. 2012. Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1α stabilization in colon carcinoma cells. Chem Res Toxicol. 25(10):2194-202. PMCID: PMC3472092
Lim KS, Liang C, Taghizadeh K, Wishnok JS, Chan W, DeMott MS, Babu IR, Tannenbaum SR, Dedon PC. 2012. In situ analysis of 8-oxo-7,8-dihydro-2’-deoxyguanosine oxidation reveals sequence- and agent-specific damage spectra. J Am Chem Soc. PMCID: PMC3503518
Lu K., Knutson CG, Wishnok JS, Fox JG, Tannenbaum SR. 2012. Serum metabolomics in a Helicobacter hepaticus mouse model of Inflammatory Bowel Disease reveals important changes in the microbiome, serum peptides, and intermediary metabolism. <http://www.ncbi.nlm.nih.gov/pubmed/22957933> J Proteome Res. 11(10):4916-26. [Epub ahead of print]. PMID: 22957933
Mangerich A, Knuston CG, Parry N, Muthupalani S, Ye W, Prestwich EG, Cui L, McFaline JL, Mobley MW, Taghizadeh K, Wishnok JS, Wogan GN, Fox JG, Tannenbaum SR, Dedon PC. 2012. Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer. PNAS 109(27):E1820-9. PMCID: PMC3390855
Dendroulakis V, Russell BS, Elmquist EC, Trudel LJ, Wogan GN, Deen WM, Dedon PC. 2012. A system for exposing molecules and cells to biologically relevant and accurately controlled steady-state concentrations of nitric oxide and oxygen. Nitric Oxide. PMCID: PMC3424365
Olipitz W, Wiktor-Brown D, Shuga J, Pang B, McFaline JL, Lonkar P, Thomas A, Mutamba JT, Greenberger JS, Samson LD, Dedon PC, Yanch JC, Engelward BP. 2012. Integrated molecular analysis indicates undetectable DNA Damage in mice after continuous irradiation at ~400-fold natural background radiation. Env Health Perspec. PMCID: PMC3440074
Li D, Delaney JC, Page CM, Yang X, Chen AS, Wong C, Drennan, CL, Essigmann, JM. 2012. Exocyclic Carbons Adjacent to the N6 of Adenine are Targets for Oxidation by the Escherichia coli Adaptive Response Protein AlkB. J Amer Chem Soc [Epub ahead of print] PMID 22512456 http://dx.doi.org/10.1021/ja3010094
Kim MY, Lim CH, Trudel LJ, Deen WM, Wogan GN. 2012. Delivery Method, Target Gene Structure, and Growth Properties of Target Cells Impact Mutagenic Responses to Reactive Nitrogen and Oxygen Species. Chem Res Toxicol [Epub ahead of print] PMCID: PMC3328651/ NIHMS356356
Charoenlap N, Shen Z, McBee ME, Muthupalani S, Wogan GN, Fox JG, Schauer DB. 2012. Alkyl hydroperoxide reductase is required for Helicobacter cinaedi intestinal colonization and survival under oxidative stress in BALB/c and BALB/c interleukin-10-/- mice. Infect Immun 80(3):921-8. PMCID: PMC3294669
Pang B, McFaline JL, Burgis NE, Dong M, Taghizadeh K, Sullivan MR, Elmquist CE, Cunningham RP, Dedon PC. 2012. Defects in purine nucleotide metabolism lead to substantial incorporation of xanthine and hypoxanthine into DNA and RNA. Proc Natl Acad Sci USA109(7):2319-24. PMCID: PMC3289290
Kim MY, Lim CH, Trudel LJ, Deen WM, Wogan GN. 2012. Delivery Method, Target Gene Structure, and Growth Properties of Target Cells Impact Mutagenic Responses to Reactive Nitrogen and Oxygen Species. Chem Res Toxicol [Epub ahead of print] NIHMS356356
Lim KS, Taghizadeh K, Wishnok JS, Babu IR, Shafirovich V, Geacintov NE, Dedon PC. 2012. Sequence-dependent variation in the reactivity of 8-Oxo-7,8-dihydro-2'-deoxyguanosine toward oxidation. Chem Res Toxicol 25(2):366-73. PMCID: PMC3288455
back to top2011
Barglow KT, Knutson CG, Wishnok JS, Tannenbaum SR, Marletta MA. 2011. Site-specific and redox-controlled S-nitrosation of thioredoxin. Proc Natl Acad Sci USA108(35): E600-6. PMCID: PMC3167493
Fox JG, Ge Z, Whary MT, Erdman SE, Horwitz BH. 2011. Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer. Mucosal Immunol 4:22-30. PMID: 20944559 [PMC journal –in process]
Fox JG, Kuipers EJ. 2011. Long-term proton pump inhibitor administration, H pylori and gastric cancer: lessons from the gerbil. Gut 60(5):567-8. PMID 21330575 [PMC journal –in process]
Garcia A, Zeng Y, Muthupalani S, Ge Z, Potter A, Mobley MW, Boussahmain C, Feng Y, Wishnok JS, Fox JG. 2011. H. hepaticus-induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial induced immune response. Cancer Res 71: 2529-2540. PMCID: PMC3071044
Ge Z, Feng Y, Muthupalani S, Lemke L.B, Taylor N, Whary MT, Fox JG. 2011. Co-infection with enterohepatic Helicobacter species can ameliorate or promote Helicobacter pylori- induced gastric pathology in C57BL/6 mice. Infect Immun 79:3861-3871. PMCID: PMC3187262
Lonkar P, Dedon PC. 2011. Reactive species and DNA damage in chronic inflammation: Reconciling chemical mechanisms and biological fates. Int J Cancer 128: 1999-2009. NIHMS 274710 [PMC journal –in process]
Mutamba JT, Svilar D, Prasongtanakij S, Wang X-H, Lin Y-C, Dedon PC, Sobol RW, Engelward BP. 2011. XRCC1 and Base Excision Repair Balance in Response to Nitric Oxide. DNA Repair 10(12):1282-93. PMID: 22041025 [PMC journal –in process]
Olipitz W, Wiktor-Brown D, Shuga J, Pang B, McFaline JL, Lonkar P, Thomas A, Mutamba JT, Greenberger JS, Samson LD, Dedon PC, Yanch JC, Engelward BP. 2011. Integrated molecular analysis indicates undetectable DNA Damage in mice after continuous irradiation at ~400-fold natural background radiation. Env Health Perspec (in press)
Slade PJ, Williams MV, Chiang A, Iffrig E, Tannenbaum SR, Wishnok JS. 2011. A filtered database search algorithm for endogenous serum protein carbonyl modifications in a mouse model of inflammation. Mol Cell Proteomics 10(10): M111.007658. PMCID: PMC3205861
Skinn BT, Lim CH, Deen WM. 2011. Nitric oxide delivery system for biological media. Free Rad Biol Med 50(2): 381-8. PMID 21073946 [PMC journal in progress]
Wang L, Chen S, Vergin KL, Giovannoni SJ, Chan SW, DeMott MS, Taghizadeh K, Cordero OX, Cutler M, Timberlake S, Alm EJ, Polz MF, Pinhassi J, Deng Z, Dedon PC. 2011. DNA phosphorothioation is widespread and quantized in bacterial genomes. Proc Natl Acad Sci USA 108: 2963-2968. PMCID: PMC3041111
Whary MT, Taylor NS, Ge Z, Muthupalani S, Versalovic J, Fox JG. 2011. Lactobacillus reuteri promotes Helicobacter hepaticus-associated typhlocolitis in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(-/-)) mice. Immunology 133:165-78. PMCID: PMC3088979 [available 2012/6/1]
2010
Li D, Delaney JC, Page CM, Chen AS, Wong C, Drennan CL, Essigmann JM. 2010. Repair of DNA alkylation damage by the Escherichia coli adaptive response protein AlkB as studied by ESI-TOF mass spectrometry. J Nucleic Acids 369434. PMCID: PMC2965429
Chan CTY, Dyavaiah M, DeMott MS, Taghizadeh K, Dedon PC, Begley TJ. 2010. A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress. PLoS Genetics 6: e1001247. PMCID: PMC3002981
Boutin SR, Shen Z, Roesch PL, Stiefel SM, Sanderson AE, Multari HM, Pridhoko EA, Smith JC, Taylor NS, Lohmiller JJ, Dewhirst FE, Klein HJ, Fox JG. 2010. Helicobacter pullorum outbreak in C57BL/6NTac and C3H/HeNTac barrier-maintained mice. J Clin Microbiol 48(5):1908-10. PMCID: PMC2863944
Chin MP, Deen WM. 2010. Prediction of nitric oxide concentrations in melanomas. Nitric Oxide 23(4):319-26. PMID: 20854923 [PMC journal –in process]
Dedon PC. 2010. Oxidation and deamination of DNA by endogenous sources. Chemical Carcinogenesis, ed. T Penning. Springer, New York.
DeMott MS, Dedon PC. 2010. The chemistry of imflammation and DNA damage: biological impact of reactive nitrogen species, in The Chemical Biology of DNA Damage, ed. Geacintov N, Broyde S, Wiley-VCH, Weinheim.
Chin MP, Schauer DB, Deen WM. 2010. Nitric oxide, oxygen, and superoxide formation and consumption in macrophages and colonic epithelial cells. Chem Res Toxicol 23(4):778-87. PMCID: PMC2879621
Erdman SE, Rao VP, Olipitz W, Taylor CL, Jackson EA, Levkovich T, Lee CW, Horwitz BH, Fox JG, Ge Z, Poutahidis T. 2010. Unifying roles for regulatory T cells and inflammation in cancer. Int J Cancer 126(7):1651-65. PMID: 19795459 [PMC journal –in process]
Lofgren J L, Whary MT, Ge Z, Muthupalani S, Taylor NS, Mobley M, Potter A, Varro A, Wang TC, Fox JC. 2010. Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology 140(1):210-20. PMCID: PMC3006487
McBee ME, Zeng Y, Parry N, Nagler CR, Tannenbaum SR, Schauer DB. 2010. Multivariate modeling identifies neutrophil- and Th17-related factors as differential serum biomarkers of chronic murine colitis. PloS ONE 5:10 e13277. PMCID: PMC2957404
North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. 2010. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proc Natl Acad Sci USA 107(40):17315-20. PMCID: PMC2951415
Prestwich EG, Dedon PC. 2010. Endogenous DNA damage, in Endogenous Toxins: Diet, Genetics, Disease and Treatment, ed. PJ O’Brien, RW Bruce. Wiley-VCH, Wienheim.
Sheh A, Lee CW, Masumura K, Rickman BH, Nohmi T, Wogan GN, Fox JG, Schauer DB. 2010. Mutagenic potency of Helicobacter pylori in the gastric mucosa of mice is determined by sex and duration of infection. Proc Natl Acad Sci USA 107:15217-22. PMCID: PMC2930535
Shrivastav N, Li D, Essigmann JM. 2010. Chemical biology of mutagenesis and DNA repair: Cellular responses to DNA alkylation. Carcinogenesis 31:59-70. PMCID: PMC2802671
Slade PG, Williams MV, Brahmbhatt V, Dash A, Wishnok JS, Tannenbaum SR. 2010. Proteins Modified by the Lipid Peroxidation Aldehyde 9,12-Dioxo-10(E)-dodecenoic Acid in MCF7 Breast Cancer Cells. Chem Res Toxicol 23(3):557-67. PMCID: PMC2908391
Margolin Y, Dedon PC. 2010. A general method for quantifying sequence effects on nucleobase oxidation in DNA. Methods Mol Biol 610:325-40. PMCID: PMC2859239
Fox JG, Feng Y, Theve EJ, Raczynski AR, Fiala JL, Doernte AL, Williams M, McFaline JL, Essigmann JM, Schauer DB, Tannenbaum SR, Dedon PC, Weinman SA, Lemon SM, Fry RC, Rogers AB. 2010. Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens. Gut 59(1):88-97. PMID: 19850960 [PMC journal –in process]
Yun BH, Dedon PC, Geacintov NE, Shafirovich V. 2010.One-electron oxidation of a pyrenyl photosensitizer covalently attached to DNA and competition between its further oxidation and DNA hole injection. Photochem Photobiol 86(3):563-70. PMID: 20408978 [PMC journal –in process]
2009
Kim MY, Trudel LJ, Wogan GN. 2009. Apoptosis induced by capsaicin and resveratrol in colon carcinoma cells requires nitric oxide production and caspase activation. Anticancer Res 29(10):3733-40. PMID: 19846903 [PMC journal –in process]
Li CQ, Kim MY, Godoy LC, Thiantanawat A, Trudel LJ, Wogan GN. 2009. Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells. Proc Natl Acad Sci USA 106(34):14547-51. PMCID: PMC2732862
Erdman SE, Rao VP, Poutahidis T, Rogers AB, Taylor CL, Jackson EA, Ge Z, Lee CW, Schauer DB, Wogan GN, Tannenbaum SR, Fox JG. 2009. Nitric oxide and TNF-alpha trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice. Proc Natl Acad Sci USA 106(4):1027-32. PMCID: PMC2633549
Lee CW, Rickman B, Rogers AB, Muthupalani S, Takaishi S, Yang P, Wang TC, Fox JG. 2009. Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice. Cancer Res 69:8166-74. PMCID: PMC2766772
Kim J-H, Heller DA, Jin H, Barone PW, Song C, Trudel LJ, Wogan GN, Tannenbaum SR, Strano MS. 2009. The rational design of nitric oxide selectivity in single-walled carbon nanotube near infrared fluorescence sensors for biological detection. Nature Chem 1(6):473-481. PMID: 21378915 [PMC journal –in process]
Kim MY, Trudel LJ, Wogan GN. 2009. Apoptosis induced by capsaicin and resveratrol in human colon carcinoma cells requires nitric oxide production and caspase activation. Anticancer Res 29:3733-3740. PMID: 19846903 [PMC journal –in process]
2008
Lim CH, Dedon PC, Deen WM. 2008. Kinetic analysis of intracellular concentrations of reactive nitrogen species. Chem Res Toxicol 21(11):2134-47. PMID:18828639 [PMC journal – in process] NIHMS91121
Meira LB, Bugni JM, Green SL, Lee CW, Pang B, Borenshtein D, Rickman BH, Rogers AB, Moroski-Erkul CA, McFaline JL, Schauer DB, Dedon PC, Fox JG, Samson LD. 2008. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J Clin Invest 118(7):2516-25. PMCID: PMC2423313
Chin MP, Schauer DB, Deen WM. 2008. Prediction of nitric oxide concentrations in colonic crypts during inflammation. Nitric Oxide 19(3):266-75. NIHMS73629
2007
Rao VP, Poutahidis T, Fox JG, Erdman SE. 2007. Breast cancer: should gastrointestinal bacteria be on our screen. Cancer Res 67(3):847-50. PMID: 17283110 [PMC journal –in process]
Delaney S, Neeley WL, Delaney JC, Essigmann JM. 2007. The substrate specificity of MutY for hyperoxidized guanine lesions in vivo. Biochemistry 46(5):1448-55. PMID: 17260974 [PMC journal –in process]
Kristiansson M, Bhat V, Babu IR, Wishnok JS, Tannenbaum SR. 2007. Comparative time-dependent analysis of potential inflammation biomarkers in lymphoma-bearing SJL mice. J Proteome Res 6, 1735-1744. PMCID: PMC2532589
Neeley WL, Delaney S, Alekseyev YO, Jarosz DF, Delaney JC, Walker GC, Essigmann JM. 2007. DNA polymerase V allows bypass of toxic guanine oxidation products in vivo. J Biol Chem 282, 12741-12748. PMID: 17322566 [PMC journal –in process]
Kim MY, Zhou X, Delaney JC, Taghizadeh K, Dedon PC, Essigmann JM, Wogan GN. 2007. AlkB Influences the Chloroacetaldehyde-Induced Mutation Spectra and Toxicity in the pSP189 supF Shuttle Vector. Chem Res Toxicol 20, 1075-1083. PMID: 17658757 [PMC journal –in process]
Pang B, Zhou X, Yu H, Dong M, Taghizadeh K, Wishnok JS, Tannenbaum SR and Dedon PC. 2007. Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation. Carcinogenesis 28, 1807-1813. PMID: 17347141 [PMC journal –in process]
Fox JG, Wang TC. 2007. Inflammation, atrophy, and gastric cancer. J Clin Invest 117: 60-69. PMCID: PMC1716216
Williams MV, Wishnok JS, Tannenbaum SR. 2007. Covalent adducts arising from the decomposition products of lipid hydroperoxides in the presences of cytrochrome C. Chem Res Toxicol 20(5):767-775. PMCID: PMC2526353
Patro JN, Wiederholt CJ, Jiang YL, Delaney JC, Essigmann JM, Greenberg MM. 2007. Studies on the replication of the ring-opened formamidopyrimidine, Fapy-dG in Escherichia coli. Biochemistry 46: 10202-10212. PMID: 17691820 [PMC journal –in process]
Kim MY, Tretyakova N, Wogan GN. 2007. Mutagenesis of the supF gene by stereoisomers of 1,2,3,4-diepoxybutane Chemical Res Toxicol 20:790-797. PMID: 17428069 [PMC journal –in process]
Borenshtein D, Nambiar PR, Groff EB, Fox JG, Schauer DB. 2007. Development of fatal colitis in FVB mice infected with Citrobacter rodentium. Infect Immun 75:3271-81. PMCID: PMC1932959
Poutahidis T, Haigis KM, Rao VP, Nambiar PR, Taylor CL, Ge Z, Watanabe K, Davidson A, Horwitz BH, Fox JG, Erdman SE. 2007. Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma. Carcinogenesis 28(12):2614-23. PMID: 17724375 [PMC journal –in process]
Nagamine CM, Rogers AB, Fox JG, Schauer DB. 2007. Helicobacter hepaticus promotes azoxymethane-initiated colon tumorigenesis in BALB/c-IL10-deficient mice. Int J Cancer 22(4):832-8. PMID: 17957786 [PMC journal –in process]
2006
Li C-Q, Pang B, Kiziltepe T, Trudel LJ, Engelward BP, Dedon PC, Wogan GN. 2006. Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type or p53-null human lymphoblastoid cells. Chem Res Toxicol 19:399-406. PMCID: PMC2570754
Dong M, Dedon PC. 2006. Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxide. Chem Res Toxicol 19:50-57. PMCID: PMC2515361
Dong M, Vongchampa V, Gingipalli L, Cloutier J-F, Kow YW, O'Connor T, Dedon PC. 2006. Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species. Mut Res 594:120-134. PMID: 16274707 [PMC journal –in process]
Li C-Q, Wright TL, Dong M, Dommels YEM, Dedon PC, Tannenbaum SR, Wogan GN. 2006. Biological role of glutathione in nitric oxide-induced toxicity in cell culture and animal models. Free Rad Biol Med 39: 1489-1498. PMCID: PMC1308863
Kraft C, Stack A, Josenhans C, Josenhans C, Niehus E, Dietrich G, Correa P, Fox JG, Falush D, Suerbaum S. 2006. Genomic changes during chronic Helicobacterpylori infection. J Bacteriol 188: 249-254. PMCID: PMC1317581
Maurer KJ, Rogers AB, Ge Z, Wiese AJ, Carey MC, Fox JG. 2006. Helicobacter pylori and cholesterol gallstone formation in C57L/J mice: a prospective study. Am J Physiol Gastrointest Liver Physiol 290: G175-182. PMID: 15825083
Tomczak MF, Gadjeva M, Wang YY, Brown K, Maroulakou I, Tsichlis PN, Erdman SE, Fox JG, Horwitz BH. 2006. Defective activation of ERK in macrophages lacking the p50/p105 subunit of NF-gB is responsible for elevated expression of IL-12 p40 observed after challenge with H. hepaticus. J Immunol 176: 1244-1251. PMID: 16394015
Rao VP, Poutahidis T, Ge Z, Nambiar PR, Horwitz BH, Fox JG, Erdman SE. 2006. Pro-inflammatory CD4+CD45RBhi lymphocytes promote mammary and intestinal carcinogenesis in ApcMin/+ mice. Can Res 66:57-61. PMID: 16397216 [PMC journal –in process]
Rogers AB, Cormier KS, Fox JG. 2006. Thiol-reactive compounds prevent nonspecific antibody binding in immunohistochemistry. Lab Invest 86: 526-533. PMID: 16534499
García A, Rogers AB, Fox JG. 2006. Renal injury is a consistent finding in Dutch Belted rabbits experimentally infected with enterohemorrhagic Escherichia coli. J Infect Dis 193:1125-1134. PMID: 16544253
Ge Z, Feng Y, Taylor N, Ohtani M, Fox JG. 2006. Colonization dynamics of altered Schaedler flora is influenced by gender, aging and Helicobacter hepaticus infection in the intestine of Swiss Webster mice. App Environ Microbiol 72: 5100-5103. PMICD: PMC1489328
Rao VP, Poutahidis T, Ge Z, Nambiar PR, Boussahmain C, Horwitz BH, FoxJG, Erdman SE . 2006. Innate immune inflammatory response against enteric bacterial pathogen Helicobacter hepaticus triggers mammary adenocarcinoma in mice. Can Res 66: 7395-7400. PMID: 16885333
Tomczak MF, Erdman SE, Davidson A, Nambiar PR, Wang YY, Luchetti D, Fox JG, Horwitz BH. 2006 Inhibition of inflammatory responses by IL-10 depends upon the presence of the p50/p105 subunit of NF-gB1. J Immunol 177(10):7332-9. PMID: 17082652
Fox JG, Wang TC. 2006. Inflammation, atrophy, and gastric cancer. J Clin Invest 117(1):60–69. PMCID: PMC1716216
Margolin Y, J-F Cloutier, Shafirovich V, Geacintov N, Dedon PC. 2006. Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation. Nature Chem Biol 2: 365-366. PMID: 16751762
Dong M and Dedon PC. 2006. Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxide. Chem Res Toxicol 19: 50-57. PMCID: PMC2515361
Dong M, Vongchampa V, Gingipalli L, Cloutier J-F, Kow YW, O'Connor T, Dedon PC. 2006. Development of enzymatic probes of oxidative and nitrosative DNA damage caused by reactive nitrogen species. Mut Res 594:120-134. PMID: 16274707
Li C-Q, Wright TL, Dong M, Dommels YEM, Dedon PC, Tannenbaum SR, Wogan GN. 2006. Biological role of glutathione in nitric oxide-induced toxicity in cell culture and animal models. Free Rad Biol Med 39: 1489-1498. PMID: 16274884
Niles J, Wishnok JS, Tannenbaum SR. 2006. Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation. Nitric Oxide 14 (2), 109-121. PMID: 16352449
Delaney JC, Smeester L, Wong C, Frick LE, Taghizadeh K, Wishnok JS, Drennan CL, Samson LD, Essigmann JM. 2006. AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo. Nature Struct Mol Biol 12: 855-860. PMID 16200073
Delaney JC, Essigmann JM. 2006. Assays for determining lesion bypass efficiency and mutagenicity of site-specific DNA lesions in vivo. Methods in Enzymology 408:1-15. PMID: 16793359
Neeley WL, Essigmann JM. 2006. Mechanisms of formation, genotoxicity and mutation of guanine oxidation products. Chem Res Toxicol 19: 491- 505. PMID: 16608160
Wiktor-Brown DM, Hendricks CA, Olipitz W, Rogers A, Engelward BP. 2006. Applications of Fluorescence for detecting Rare Sequence Rearrangements in vivo. Cell Cycle (23):2715-9.
Koturbash I, Rugo RE, Hendricks CA, Loree J, Thibault B, Kutanzi K, Pogribny I, Yanch JC, Engelward BP, Kovalchuk O. 2006. Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo. Oncogene 1-9.
Kim MY, Wogan GN. 2006. Mutagenesis of the supF Gene of pSP189 replicating in AD293 cells co-cultivated with activated macrophages: roles of nitric oxide and reactive oxygen species. Chem Res Toxicol 19:1483-1491. PMID: 17112236
Maurer KJ, Rogers AB, Ge Z, Wiese AJ, Carey MC, Fox JG. 2006. Helicobacter pylori and cholesterol gallstone formation in C57L/J mice: a prospective study. Am J Physiol Gastrointest Liver Physiol 290:G175-182. PMID: 16109843
Rao VP, Poutahidis T, Ge Z, Nambiar PR, Horwitz BH, Fox JG, Erdman SE. 2006. Pro-inflammatory CD4+CD45RBhi lymphocytes promote mammary and intestinal carcinogenesis in ApcMin/+ mice. Cancer Res 66:57-61. PMID: 16397216
Whary MT, Danon SJ, Feng Y, Ge Z, Sundina N, Ng V, Taylor NS, Rogers AB, Fox JG. 2006. Rapid onset of ulcerative typhlocolitis in B6.129P2-IL10tm1Cgn (IL-10-/-) mice infected with Helicobacter trogontum is associated with decreased colonization of Altered Schaedler’s Flora. Infect Immun 74(12):6615-23. PMCID: PMC169870
Jarosz DF, Godoy VG, Delaney, JC, Essigmann, JM, Walker GC. 2006. A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates. Nature 439(7073):225-8. PMID: 16407906
2005
Dedon P. 2005. Diverse mechanisms of endogenous nucleobase deamination in DNA and RNA, in Advances in Molecular Toxicology, ed. J. Fishbein, Wiley, NY.
Yu H, Venkatarangan L, Wishnok JS, Tannenbaum SR. 2005. Quantitation of Four Oxidation Products from Reaction of DNA with Varying Doses of Peroxynitrite. Chem Res Toxicol 18: 1849-1857. PMCID: PMC2526347
Jonnalagadda VS, Matsuguchi T, Engelward BP. 2005. Interstrand crosslink-induced homologous recombination carries an increased risk of deletions and insertions. DNA Repair 4: 594-605. PMID: 15811631
Zacharia IG, Deen WM. 2005. Diffusivity and solubility of nitric oxide in water and saline. Ann Biomed Engr 33: 214-222. PMID: 15771275
Robertson BR, O’Rourke JL, Neilan BA, Vandamme P, On SL, Fox JG, Lee A. 2005. Mucispirillum schaedleri gen. nov. sp. nov. a spiral shaped bacterium colonising the mucus layer of the gastrointestinal tract of laboratory rodents. International J Sys Evol Bacteriol 55:1199-1204. PMID: 15879255
Pena JA, Ng V, Rogers AB, Ge Z, Li S, Fox JG, Versalovic J. 2005. Probiotic lactobacillus diminishes Helicobacter hepaticus-induced inflammatory bowel disease in IL-10 deficient mice. Infect Immun 73: 912-920. PMID: 15664933
Niles J, Wishnok JS, Tannenbaum SR. 2005. Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation. Nitric Oxide 14 (2):109-21. pMID: 16352449
Nalwaya N, Deen WM. 2005. Nitric oxide, oxygen, and superoxide formation and consumption in macrophage cultures. Chem Res Toxicol 18(3):486-93. PMID: 15770888
Maurer KJ, Ihrig MM, Rogers AB, Ng V, Bouchard G, Carey MC, Fox JG. 2005. Identification of cholelitogenic enterohepatic Helicobacter species and their role in murine cholesterol gallstone formation. Gastroenterology 128: 1023-1033. PMID 15825083
Li C-Q, Wogan GN. 2005. Nitric oxide as a modulator of apoptosis. Cancer Lett 226:1-15. PMID: 16004928
Kiziltepe T, Yan A, Dong M, Jonnalagadda VS, Dedon PC, Engelward BP. 2005. Delineation of the chemical pathways underlying nitric oxide-induced homologous recombination in mammalian cells. Chem Biol 12: 357-369. PMID: 15797220
Kim MY, M. Dong, Dedon PC, Wogan GN. 2005. Effects of peroxynitrite dose and dose-rate on DNA damage and mutation in the supF shuttle vector. Chem Res Toxicol 18: 76-86. PMID: 15651852
Ihrig M, Whary MT, Dangler CA, Fox JG. 2005. Gastric helicobacter infection induces a Th2 phenotype but does not elevate serum cholesterol in mice lacking inducible nitric oxide synthase. Infect Immun 73: 1664-1670. PMID: 15731067
Henderson PT, Neeley WL, Delaney JC, Gu F, Niles JC, Hah SS, Tannenbaum SR, Essigmann JM. 2005. Urea lesion formation in DNA as a consequence of 7,8-dihydro-8-oxoguanine oxidation and hydrolysis provides a potent source of point mutations. Chem Res Toxicol 18,12-18. PMID: 15651843
Franco AT, Israel DA, Washington MK, Krishna U, Fox JG, Rogers AB, Neish AS, Collier-Hyams L, Perez-Perez GI, Hatakeyama M, Whitehead R, Gaus K, O'brien DP, Romero-Gallo J, Peek RM Jr. 2005. Activation of {beta}-catenin by carcinogenic Helicobacter pylori. Proc Natl Acad Sci USA 102:10646-51. PMCID: PMC1180811
Erdman SE, Sohn JJ, Rao VP, Nambiar PR, Ge Z, Fox JG, Schauer DB. 2005. CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice. Cancer Res 65:3998-4004. PMID: 15899788
Delaney JC, Smeester L, Wong C, Frick LE, Taghizadeh K, Wishnok JS, Drennan CL, Samson LD, Essigmann JM. 2005. AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo. Nat Struct Mol Biol 12, 855-860. PMID: 16200073
Cai X, Stoicov C, Li H, Carlson J, Whary M, Fox JG, Houghton J. 2005. Overcoming Fas mediated apoptosis accelerates Helicobacter induced gastric cancer in the mouse. Cancer Res 65:10912-10919. PMID: 16322238
Boutin SR, Shen Z, Rogers AB, Feng Y, Ge Z, Xu S, Sterzenbach T, Josenhans C, Schauer DB, Suerbaum S, Fox JG. 2005. Different Helicobacter hepaticus strains with variable genomic content induce various degrees of hepatitis. Infect Immun 73:8449-8452. PMCID: PMC1307073
Bhat VB, Choi MH, Wishnok JS, Tannenbaum SR. 2005. Comparative plasma proteome analysis of lymphoma-bearing SJL mice. J Proteome Res 4: 1814-1825. PMID: 16212437
2004
Yu H, Niles J, Wishnok JS, Tannenbaum SR. 2004. Spirodihydantoin is a Minor Product of 5-Hydroxyisourate in Urate Oxidation. Organic Lttrs 6(19), 3417-3420. PMID: 15355066
Young VB, Knox KA, Cortez JS, Wang W, Mansfield LS, Rogers A, Fox JG, Meek K, Schauer DB. 2004. In vitro and in vivo characterization of Helicobacter hepaticus cytolethal distending toxin mutants. Infect Immun 72: 2521-2527. PMID: 15102759
Wang C, Deen WM. 2004. Peroxynitrite delivery methods for toxicity studies. Chem Res Toxicol 17: 32-44. PMID: 14727917
Tannenbaum SR, Ji-Eun Kim. 2004. Controlled S-nitrosation. Nat Chem Bio 1(2), 2-3. PMID: 16408013
Sarma-Rupavtarm RB, Ge Z, Schauer DB, Fox JG, Polz MF. 2004. Spatial distribution and stability of the eight microbial species of the Altered Schaedler Flora in the gastrointestinal tract of mice. Applied Environ Microbiol 70: 2791-2800. PMID: 15128534
Rogers AB, Fox JG. 2004. Rodent models of infectious gastrointestinal and liver cancer. Am J Physiol Gastrointest Liver Physiol 286: G361-G366.
Rogers AB, Boutin SR, Whary MT, Sundina N, Ge Z, Cormier K, Shen Z, Fox JG. 2004. Progression of chronic hepatitis and preneoplasia in Helicobacter hepaticus-infected. A/JCr mice Toxicol Path 32: 668-677.
Niles JC, Wishnok JS, Tannenbaum SR. 2004. Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of peroxynitrite: kinetic and mechanistic studies with 18O. Chem Res Toxicol 17, 1510-1519. PMID: 15540949
Niles JC, Wishnok JS, Tannenbaum SR. 2004. Mass Spectrometric Identification of 4-hydroxy-2,5-dioxo-imidazolidine-4-carboxylic acid during One-Electron Oxidation of 8-oxoguanosine by Peroxynitrite and KHSO5/CoCl2. Chem Res Toxicol 17, 1501-1509. PMID: 15540948
Neeley WL, Henderson PT, Essigmann JM. 2004. Efficient synthesis of DNA containing the guanine oxidation-nitration product 5-guanidino-4-nitroimidazole: generation by a postsynthetic substitution reaction. Org Lett. 6, 245-248. PMID: 14723539
Neeley WL, Delaney JC, Henderson PT, Essigmann JM. 2004. In vivo bypass efficiencies and mutational signatures of the guanine oxidation products 2-aminoimidazolone and 5-guanidino-4-nitroimidazole. J. Biol. Chem. 279: 43568-43573. PMID: 15299010
Neeley WL, Henderson PT, Essigmann JM. 2004. Efficient synthesis of DNA containing the guanine oxidation-nitration product 5-guanidino-4-nitroimidazole: Generation by a post-synthetic substitution reaction. Organic Letters. 6: 245-248. PMID: 14723539
Nalwaya N, Deen WM. 2004. Peroxynitrite exposure of cells co-cultured with macrophages. Ann. Biomed. Engr. 32: 664-676. PMID: 15171621
Liu Z, Hergenhahn M, Schmeiser H, Wogan GN, Hong A, and Hollstein M. 2004. Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene. Proc. Nat. Acad. Sci. (USA). 101: 2963-2968. PMCID: PMC365728
Houghton J, Stoicov C, Nomura S, Rogers AB, Carlson J, Li H, Cai X, Fox JG, Goldenring JR, Wang TC. 2004. Gastric cancer originating from bone marrow derived stem cells. Science 306: 1568-1571. PMID: 15567866
Dedon P, Tannenbaum SR. 2004. Reactive Nitrogen Species in the Chemical Biology of Inflammation. Arch. Biochem & Biophys 423,12-22. PMID:14989259
Boutin SR, Rogers AB, Shen Z, Love JA, Fry R, Nambiar PR, Suerbaum S, Fox JG. 2004. Hepatic temporal gene expression profiling in Helicobacter hepaticus infected A/JCr mice. Toxicol Pathol 32: 678-693. PMID: 15513911
Miller B.H., Fratti R.A., Poschet J.F., Timmins G.S., Master S.S., Burgos M., Marletta M.A., Deretic V. 2004. Mycobacteria inhibit nitric oxide sythase recruitment to phagosomes durring macrophage infection. PubMed
Liu Z., Hergenhahn M., Schmeiser H.H., Wogan G.N., Hong A., Hollstein M. Related Articles, Books Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene. Proc Natl Acad Sci U S A. 2004 Feb 19. Pubmed.
Niles J., Wishnok J.S., Tannenbaum S.R. 2004. Mass Spectrometric Identification of 4-hydroxy-2,5-dioxo-imidazolidine-4-carboxylic acid during One-Electron Oxidation of 8-oxoguanosine by Peroxynitrite and KHSO5/CoCl2. Submitted Chemical Research in Toxicology.
Niles J., Wishnok J.S., Tannenbaum S.R. 2004. Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low fluxes of perooxynitrite: kinetic and mechanistic studies with 18O. Submitted Chemical Research in Toxicology.
2003
Hofseth L.J., Hussain S.P., Wogan G.N., Harris C.C. Nitric oxide in cancer and chemoprevention. Free Radic Biol Med. 2003 Apr 15;34(8):955-68. Review. Pubmed.
Pamir B., Wogan G.N. Carbon dioxide modulation of peroxynitrite-induced mutagenesis of the supF gene in pSP189. Chem Res Toxicol. 2003 Apr;16(4):487-92. Pubmed.
Caulfield J.L., Wishnok J.S., Tannenbaum S.R.. 2003. Nitric oxide-induced interstrand cross-links in DNA. Chem. Res. Toxicol., Chem Res Toxicol. 2003 May;16(5):571-4.
Dedon P., and Tannenbaum S.R. 2003. Reactive Nitrogen Species in the Chemical Biology of Inflammation. Submitted BBA Reviews AMCS Issue. PubMed.
Hurshman A.R., Krebs C., Edmondson D.E., Marletta M.A. 2003 Ability of tetrahydrobiopterin analouges to support catalysis by inducible nitric oxe synthase: formation of a pterinn radical is required for enzym activity.PubMed
Dong M., Wang C.,Deen W.M., Dedon P.C. 2003. Controlled exposure of DNA to nitric oxide produces a spectrum of deamination products that does not include 2'-deoxyoxanosine. Chem. Res. Toxicol., submitted.
Henderson T., Delaney J.C., Muller J.G., Neeley W.L., Tannenbaum S.R., Burrows C.J., Essigmann J.M. 2003. The Hydantoin Lesions Formed from Oxidation of 7,8-Dihydro-8-oxoguanine Are Potent Sources of Replication Errors in Vivo. Biochemistry. 42(31), 9257-9262.
Kim J., Tannenbaum S.R. 2003. S-nitrosation regulates the activation of endogenous procapase-9 in HT-29 human colon carcinoma cells.Biol Chem. 2004 Mar 12;279(11):9758-64.
Nikov G., Bhat V., Wishnok J.S., Tannenbaum, S.R. 2003. Analysis of nitrated proteins by nitrotyrosine-specific affinity probes and mass spectrometry. Anal. Biochem., in press. PubMed
Niles J., Wishnok J.S., Tannenbaum S.R. 2003. Spiroiminodihydantoin and guanidinohydantoin are the dominant products of 8-oxoguanosine oxidation at low peroxynitrite fluxes. PubMed
Spiering M.M., Ringe R., Murphy J.R., Marletta M.A. 2003. Metal stoichiometry and functional studies of the diphtheria toxin repressor. Submitted. PubMed
Spiering M.M., Marletta M.A. 2003. Deactivation of the diphtheria toxin repressor by nitric oxide. Submitted.
Spiering M.M., Marletta M.A. 2003. Trace elements and nitric oxide function. J. Nutrition, in press. PubMed
Tannenbaum S.R., Schauer D. 2003. Chapter 21. The role of nitric oxide and oxygen radicals in colon carcinogenesis. In: Exogenous Factors in Colonic Carcinogenesis - Falk Symposium 128, Scheppach and Scheurlen, eds., Kluwer Academic Publishers, in press.
Vongchampa V., Dong D., Gingipalli Y., Kow W., O'Connor T., Dedon P.C. 2003. Differential recognition of deoxyxanthosine by base excision repair enzymes. Mutation Res., submitted.
Wang C., Deen W.M. 2003. Nitric oxide delivery system for cell culture studies. Ann.Biomed. Engr., 31, 65-79.
Wright T.L., Li C-Q., Trudel L.J., Wogan G.N., Tannenbaum S.R. 2003. Determination of Nitric oxide-induced effects on tissue levels of glutathione and mitochondrial membrane potential. Methods in Enzymology, Elsevier Science (USA). 359, 319-328.
Yu H., Niles J., Wishnok J.S., Tannenbaum S.R. 2003. Search for Spirodihydantoin from Urate Oxidation: Insights into the Mechanism of Decomposition of 5-Hydroxyisourate. Submitted Biochemistry.
Yu H., Wishnok J.S., Tannenbaum S.R. 2003. Synthesis of 3,7,8-15N3-N1-(beta-D-erythro-pentofuranosyl)-5-guanidinohydantoin. Journal of Labelled Compounds and Radiopharmaceuticals. In press.
2002
Chen B., Deen W.M. 2002. Effect of liquid depth on the synthesis and oxidation of nitric oxide in macrophage cultures. Chem.Res. Toxicol. 15, 490-496.
Hurshman A.R, Marletta M.A. 2002. Reactions catalyzed by the heme domain of inducible nitric oxide synthase: evidence for the involvement of tetrahydropiopterin in electron transfer. PubMed
Ballou D.P., Zhao Y., Brandish P.E., Marletta M.A. 2002, Revisiting the kenetics of nitric oxide (NO) binding to soluble guanylate cylase: the simple NO-Binding model is incorrect. PubMed
Deen W.M., Tannenbaum S.R., Beckman J.S. 2002. Protein tyrosine nitration and peroxynitrite. Comment. FASEB J. 16, 1144.
Gu F., Stillwell W.G., Wishnok J.S., Shallop A.J., Jones J.R., Tannenbaum S.R. 2002. Peroxynitrite-induced reactions of synthetic oligo 2'-deoxynucleotidesand DNA containing guanine: Formation and stability of a 5-guanidino-4-nitroimidazolelesion. Biochem.,41, 7508-7518.
Lee J.M., Niles J.C, Wishnok J.S., Tannenbaum S.R. 2002. Peroxynitritereacts with 8-nitropurines to yield 8-oxopurines. Chem.Res. Toxicol., 15, 7-14.
Spek, E.J., L.N. Vuong, T. Matsuguchi, M.G. Marinus, and B.P. Engelward.2002. Nitric oxide-induced homologous recombination in Escherichia coliis promoted by DNA glycosylases. J. Bacteriol., 184, 3501-3507.
Zhuang J.C., Lin, D., Lin C., Jethwaney C., Wogan G.N. 2002. Genotoxicity associated with NO production in macrophages and co-cultured target cells.FreeRadic.Biol.Med., 33, 94-102.
2001
Marletta M.A. 2001. Another activation switch for endothelial nitric oxide synthase: why does it have to be so complicated? PubMed
Rusche K.M., Marletta M.A. 2001. Reconstitution of pterin-free inducible nitric oxide synthase. PubMed
Henderson P.T., Gu F., Delaney J.C., Tannenbaum S.R., Essigmann J.M. 2001. Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo. Biochemistry,41, 914-921.
Ihrig, M., C.A. Dangler, J.G. Fox. 2001. Mice lacking inducible nitricoxide synthase develop spontaneous hypercholesterolaemia and aortic atheromas.Atherosclerosis 156, 103-107.
Jiao K., Mandapati S., Skipper P.L., Tannenbaum S.R., Wishnok J.S. 2001. Site-selective nitration of tyrosine in human serum albumin by peroxynitrite.Analyt.Biochem. 293, 43-52.
Niles J.C., Wishnok J.S., Tannenbaum S.R. 2001. Spiroiminodihydantoinis the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols, and guanosine photo-oxidation by methylene blue.OrganicLetts., 3, 963-966.
Niles J.C., Wishnok J.S., Tannenbaum S.R. 2001. A novel nitroimidazole compound formed during the reaction of peroxynitrite with 2',3',5'-tri-O-acetyl-guanosine.J.American Chem. Soc., 49, 12147-12151.
Spek, E.J., T.L. Wright, M.S. Stitt, N.R. Taghizadeh, S.R. Tannenbaum, M.G. Marinus and B.P. Engelward. 2001. Recombinational repair is critical for survival of Escherichia coli exposed to nitric oxide. J. Bacteriol.,183, 131-138.
Tannenbaum, S.R., 2001. A new paradigm for DNA damage by reactive oxygen and nitrogen species. Food & Food Ingredients Journal of Japan. 194, 5-9.
Tretyakova N.Y., Wishnok J.S., Tannenbaum S.R. 2001. Peroxynitrite-induced secondary oxidative lesions at guanine nucleobases: Chemical stability and recognition by the Fpg DNA repair enzyme. Chem.Res. Toxicol., 13, 658-664.
Tretyakova N.Y., Matter B., Ogdie A., Wishnok J.S., Tannenbaum S.R. 2001. Locating nucleobase lesions within DNA sequences by MALDI-TOF mass spectral analysis of exonuclease ladders. Chem.Res. Toxicol., 14, 1058-1070.
2000
Marnett, L.J., Wright T.L., Crews B.C., Tannenbaum S.R., Morrow J.D. 2000. Regulation of prostaglandin biosynthesis by nitric oxide is revealed by targeted deletion of inducible nitric oxide synthase. J. Biol. Chem.18, 13427-13430
Niles J.C., Wishnok J.S., Tannenbaum S.R. 2000. A novel nitration product formed during the reaction of peroxynitrite with 2
Perry J.M., Zhao Y., Marletta M.A. 2000. Cu2+ and Zn2+ inhibit nitric-oxide synthase through an interaction with the reductase domain. PubMed
Tannenbaum S.R. 2000. DNA damage by nitrogen and oxygen free radicals and its modulation by dietary constituents. IN: Carcinogenic and Anticarcinogenic Factors in Food: Novel Concepts?. Chapter 14, 228-233.
Tretyakova N.Y., Wishnok J.S., Tannenbaum S.R. 2000. Peroxynitrite-induced secondary oxidative lesions at guanine nucleobases: chemical stability and recognition by the Fpg DNA repair enzyme. Chem. Res. Tox. 13, 390-396.
Tretyakova, N.Y., S. Burney, B. Pamir, J.S. Wishnok, P.C. Dedon, G.N. Wogan and S.R. Tannenbaum. Peroxynitrite-induced DNA damage: Correlation with the mutational spectrum. Mutation Res. 447, 287-303, 2000.
Zhuang J.C., Wright T.L., deRojas-Walker T., Tannenbaum S.R., Wogan G.N. 2000. Nitric oxide-induced mutations in the HPRT gene of human lymphoblastoid TK6 cells and in Salmonella typhimurium. Environ. Mol. Mutagen. 35, 39-47.
Zhuang J.C., Wright T.L., de Rojas-Walker T., Tannenbaum S.R., Wogan G.N. Related Articles, Books, LinkOut Response to Dr. O'Neill Environ Mol Mutagen. 2000;36(4):337-8. No abstract available. Pubmed
Zhuang J.C., Wright T.L., deRojas-Walker T., Tannenbaum S.R., Wogan G.N. Related Articles, Books, LinkOut Nitric oxide-induced mutations in the HPRT gene of human lymphoblastoid TK6 cells and in Salmonella typhimurium. Environ Mol Mutagen. 2000;35(1):39-47. Pubmed
1999
Burney S., Caulfield J.L, Niles J.C., Wishnok J.S., Tannenbaum S.R. 1999. The chemistry of DNA damage from nitric oxide and peroxynitrite.MutationRes. 424, 37-49.
Zhao Y., Brandish P.E., Ballou D.P., Marletta M.A. 1999. A molecular basis for nitric oxide sensing by soluable guanylate cyclase. PubMed
Hurshman A.R., Krebs C., Edmondson D.E., Huynh B.H., Marletta M.A. 1999. Formation of pterin radical in the reaction of the heme domain of inducible nitric oxide synthase with oxygen. PubMed
Barker S.L., Zhao Y., Marletta M.A., Kopelman R. 1999. Cellular applications of a sensitive and selective fiber-optic nitric oxide biosensor base on a dye-labled heme domain of soluable guanylate cyclase. PubMed.
Lee Y., Marletta M.A., Martasek P., Roman L.J., Masters B.S., Silverman R.B. 1999. Conformationally-restricted arginine analogues as alternative substrates and inhibitors of nitric oxide synthase. PubMed
Denninger J.W., Marletta M.A. 1999. Guanylate Cyclase and the .No/cGMP signaling pathway. PubMed
Ludwig M.L., Marletta M.A. 1999. A new decoration for nitric oxide synthase - a Zn(Cys)4 site. PubMed
Burney S., Niles J.C., Dedon P.C., Tannenbaum S.R. 1999. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite. Chem.Res Toxicol., 12, 513-520.
Jackson L., Trudel L.J., Fox N.G., Lipman N.S. 1999. Monoclonal antibody production in murine ascites I: Clinical and pathological features. LabAnim. Sci. 49, 70-80.
Jackson L., Trudel L.J., Fox J.G., Lipman N.S. 1999. Monoclonal antibody production in murine ascites II: Production characteristics. Lab. Anim.Sci. 49, 81-86.
Jeong J.K., Wogan G.N., Lau S.S., Monks T.J. 1999. Quinok-glutathione conjugate induced mutation spectrum in the supF gene replicated in human AD293 cells and bacterial MBL50 cells. Cancer Res., 59, 3641-3645.
Niles J.C., Burney S., Singh S.P., Wishnok J.S., Tannenbaum S.R. 1999. Peroxynitrite reaction products of 3',5'-di-O-acetyl-8-oxo-7,8-dihydro-2'deoxyguanosine. Proc. Natl. Acad. (USA) 96, 11729-11734.
Tretyakova N.Y., Niles J.C., Burney S., Wishnok J.S., Tannenbuam S.R. 1999. Peroxynitrite-induced reactions of synthetic oligonucleotides containing 8-oxoguanone. Chem. Res. Toxicol., 12, 459-466.
1998
Caulfield J.L., Wishnok J.S., Tannenbaum S.R. 1998. Nitric oxide-induced deamination of cytosine and guanine in deoxynucleosides and oligonucleotides. J. Biol. Chem.. 273(21), 12689-12695.
Kreutzer D.A., Essigmann J.M. 1998. Oxidized, deaminated cytosines are a source of C --> T transitions in vivo. Proc.Natl. Acad. Sci. (USA), 95, 3578-3582.
Marletta M.A., Hurshman A.R., Rusche K.M. 1998. Catalyst by nitric oxide sythase. PubMed
Perry J.M., Marletta M.A. 1998. Effects of transition metals on nitric oxide synthase catalysis. PubMed
Zhao Y., Hoganson C., Babcock G.T., Marletta M.A. 1998. Structural changes in the heme proximal pocket induced by nitric oxide binding to soluable guanylate cyclase.PubMed
Perry J.M., Moon N., Zhao Y., Dunham W.R., Marletta M.A. 1998. The High-potential flavin and heme of nitric oxide synthase are not magnetically linked: implicaitons for electron transfer. PubMed
Stone J.R., Marletta M.A. 1998. Synergistic activation of soluable guanylate cyclase by YC-1 and carbon monoxide: implications for the role of cleavage of the iron-histidine bond during activation by nitric oxide. PubMed
Brandish P.E., Buechler W., Marletta M.A. 1998. Regeneration of the ferros heme of the soulble guanylate cyclase from the nitric oxide complex: acceleration by thiols and oxyhemoglobin. PubMed
Rusche K.M., Spiering M.M., Marletta M.A. 1998. Recations Catalyzed by tetrahydrobiopterin-free nitric oxide sythase. PubMed
Nair J., Gal A., Tamir S., Tannenbaum S.R., Wogan G.N., Bartsch H. 1998. Lipid peroxidation-induced etheno adducts in spleen DNA of SJL mice stimulated to overproduce nitric oxide. Carcinogenesis. 19(12), 2081-2084.
Zhuang J.C., Lin D., Lin C., Wogan G.N. 1998. Mutagenesis associated with nitric oxide production in macrophages. Proc.Nat. Acad. Sci. USA, 95, 8286-8291.
Zhuang J.C., Lin D., Lin C., Wogan G.N. Mutagenesis associated with nitric oxide production in macrophages. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8286-91. Pubmed
1997
Zhuang J.C., Wogan G.N. Growth and viability of macrophages continuously stimulated to produce nitric oxide.Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11875-80. Pubmed
Clague M.J., Wishnok J.S., Marletta M.A. 1997. Formation of N Delta-cyanoornithine from NG-hydroxy-L-Arginine and hydrogen peroxide by neuronal nitric oxide synthase: implications for mechanism. PubMed
Zhang H.Q., Fast W., Marletta M.A., Martasek P., Silverman, R.B. 1997. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. PubMed
Steven-Truss R., Beckingham K., Marletta M.A. 1997. Calcium binding sites of calmodulin and electron transfer by neuronal nitic oxide synthase. PubMed
Silverman R.B., Huang H., Marletta M.A., Martasek P. 1997. Selective inhibition of neuronal nitic oxide synthase by N omega-nitroarginine- and phenylalanine-containing Dipeptides and dipeptide esters. PubMed
Fast W., Levsky M.E., Marletta M.A., Silverman R.B. 1997. N omega-propargyl-L-arginine and N omega-hydroxy-N omega-propargyl-L-arginine are inhibitors, but not inactivators, of neuronal and macrophage nitric oxide sythases. PubMed
Burney S., Tamir S., Gal A., Tannenbaum S.R. 1997. A Mechanistic Analysis of Nitric Oxide-Induced Cellular Toxicity. Nitric Oxide: Biology and Chemistry, 1, 130-144.
Gal A., Tamir S., Kennedy L.J., Tannenbaum S.R., Wogan G.N. 1997. Nitrotyrosine formation, apoptosis and oxidative damage: relationships to nitric oxide production in SJL mice bearing the RcsX tumor. Cancer Res., 57, 1823-1828.
Kennedy L.J., Moore Jr. K., Caulfield J.L., Tannenbaum S.R., Dedon P.C. 1997. Quantitation of 8-Oxoguanine and Strand Breaks Produced by Four Oxidizing Agents. Chem. Res. Toxicol., 10, 386-392.
1996
Caulfield J.L., Singh S.P., Wishnok J.S., Deen W.M., Tannenbaum S.R. 1996. Bicarbonate Inhibits N-Nitrosation in Oxygenated Nitric Oxide Solutions. J. Biol. Chem., 271, 25859-25863.
Richards M.K., Clague M.J., Marletta M.A. 1996. Characterization of C415 mutants of neuronal nitric oxide synthase. PubMed
Gal A., Tamir S., Tannenbaum S.R., Wogan G.N. 1996. Nitric oxide production in SJL mice bearing the RcsX lymphoma: A model for in vivo toxicological evaluation of NO. Proc. Natl. Acad. Sci. U.S.A., 93, 11499-11503.
Keshive M., Singh S.P., Wishnok J.S., Tannenbaum S.R., Deen W.M. 1996. Kinetics of S-Nitrosation of Thiols in Nitric Oxide Solutions. Chem. Res. Toxicol., 9, 988-993.
Leaf C.D., Tannenbaum S.R. 1996. The role of dietary nitrate and nitrite in human cancer. IN: Nutrition and cancer Prevention, Ch. 17, 317-324.
Deinum G., Stone J.R. Babcock G.T., Marletta M.A. 1996. Binding of nitric oxide and carbon monoxide to soluble guanylate cyclase as observed with Resonance raman spectropy. PubMed
Luperchio A., Tamir S., Tannenbaum S.R. 1996. NO-induced oxidative stress and glutathione metabolism in rodent and human cells. Free Radical Biol. Med., 21, 513-519.
Singh S.P., Wishnok J.S., Keshive M., Deen W.M., Tannenbaum S.R. 1996. The chemistry of S-Nitrosoglutathione. Proc. Natl. Acad. Sci. U.S.A., 93, 14428-14433.
Tamir S., Burney S., Tannenbaum S.R. 1996. DNA damage by nitric oxide. Chem. Res. Toxicol., 9(5), 821-827.
Tamir S., Tannenbaum S.R. 1996. The role of nitric oxide (NO) in the carcinogenic process. Biochim Biophys Acta, 1288, F31-F36.
Tamir S., deRojas-Walker J.S., Wishnok J.S., Tannenbaum S.R. 1996. DNA damage and genotoxicity by nitric oxide. Methods in Enzymology Series, 269, 230-243.
Stone J.R., Marletta M.A. 1996. Spectral and kinetic studies on the activation of soluble guanylate cyclase by nitric oxide. PubMed
Wishnok J.S., Glogowski J.A., Tannenbaum S.R. 1996. Quantitation of nitrate, nitrite, and nitrosating agents. Methods in Enzymology Series, 268, 130-141.
1995
Stevens-Truss R., Marletta M.A. 1995. Interaction of camodulin with the inducible murine microphage nitric oxide synthase. PubMed
Castillo, L., M. Sanchez, J. Vogt, T.E. Chapman, T.C. deRojas-Walker, S.R. Tannenbaum, A.M. Ajami, and V.R. Young. 1995. Plasma arginine, citrulline, and ornithine kinetics in adults, with observations on nitric oxide synthesis. Am. J. Phys., 268, E360-E367.
deRojas-Walker T.C., Tamir S., Ji H., Wishnok J.S., Tannenbaum S.R. 1995. Nitric Oxide Induces Oxidative Damage in Addition to Deamination in Macrophage DNA. Chem. Res. Toxicol., 8, 473-477.
Kurrek M.M., Castillo L., Block K.D., Tannenbaum S.R., Zapol W.M. 1995. Inhaled nitric oxide does not alter enotoxin-induced nitric oxide synthase activity during rat lung perfusion. J. Physiol., 79, 1088-1092.
Lewis R.S., Tannenbaum S.R., Deen W.M. 1995. Kinetics of N-nitrosation in oxygenated nitric oxide solutions at physiological pH:role of nitrous anhydride and effects of phosphate and chloride. J. Am. Chem. Soc., 117, 3933-3939.
Lewis R.S., Tamir S., Tannenbaum S.R., Deen W.M. 1995. Kinetic Analysis of the Fate of Nitric Oxide Synthesized by Macrophages in Vitro. J. Biol. Chem., 270, 29350-29355.
Nunoshiba T., deRojas-Walker T., Tannenbaum S.R., Demple B. 1995. Roles of nitric oxide in inducible resistance of Escherichia coli to activated murine macrophages. Infect. Immun., 63, 794-798.
Pufahl R.A., Wishnok J.S., Marletta M.A. 1995. Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase. Biochemistry.,34, 1930-41.
Warner R.L., Paine R. 3rd, Christensen P.J., Marletta M.A., Richards M.K., Wilcoxen S.E., Ward P.E. 1995. Lung sources and cytokine requirements for in vivo expression of inducible nitric oxide synthase. PubMed: Am J Respir Cell Mol Biol. 1995 Jun;12(6):649-61.
Tannenbaum S.R. 1995. Safety evalutaion of inhaled nitric oxide. IN: Lung Biology in Health and Disease, 247-250.
Tannenbaum S.R., Wishnok J.S. 1995. Genotoxicity of nitric oxide via nitrosative deamination of bases in DNA. IN: Biology of Nitric Oxide, 206-208.
Hurshman A.R., Marletta M.A. 1995. Nitric oxide complexes of inducible nitric oxide synthase: spectral characterization and effect on catalytic activity. PubMed
Pufahl R.A., Wishnok J.S., Marletta M.A. 1995. Hydrogen peroxide-supported oxidation of NG-hydroxy-L-arginine by nitric oxide synthase. PubMed
Tamir S., deRojas-Walker T.C., Gal A., Weller A.H., Li H., Fox J.G., Wogan G.N., Tannenbaum S.R. 1995. Nitric oxide production in relation so spontaneous B cell lymphoma and myositis in SJL mice. Cancer Res., 55, 4391-4397.
1994
Carter E.A., deRojas-Walker T.C., Tamir S., Tannenbaum S.R., Yu Y.-M., Tompkins R.G. 1994. Nitric oxide production is intensely and persistently increased in tissues by thermal injury. J. Biochem., 304, 201-204.
Tannenbaum S.R., Tamir S., deRojas-Walker T.C., Wishnok J.S. 1994. DNA damage and cytotoxicity by nitric oxide. IN: ACS Symposium Series 553, Nitrosamines and Related N-Nitroso Compounds: Chemistry and Biochemistry, p.120-135.
Olken N.M., Osowa Y., Marletta M.A. 1994. Characterization of the inactivation of nitric oxide by NG-methyl-L-arginine: evidence for heme loss. PubMed
Richards M.K., Marletta M.A. 1994. Characterization of the neuronal nitric oxide synthase and a c415H mutant, purified from a baculovirus overexpression system. PubMed
Green S.J., Scheller L.F., Marletta M.A., Seguin M.C., Klotz F.W., Slayter M., Nelson B.J., Nacy C.A. 1994. Nitric Oxide: cytokine-regulation of nitric oxide in host resistance to intercellular pathogens. PubMed
Marletta M.A. 1994. Nitric oxide synthase: aspects concerning structure and catalysis.PubMed
Marletta M.A. 1994. Approaches toward selective inhibition of nitric oxide synthase. PubMed
Stone J.R., Marletta M.A. 1994. Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states. PubMed
Hevell J.M., Marletta M.A. 1994. Nitric-oxide synthase assays. PubMed
1993
Olken N.M., Marletta M.A. 1993. NG-methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase. PubMed
Soman N.R., Fox J.G., Murphy J.C., Tannenbaum S.R., Wogan G.N. 1993 Expression of the trp-met rearrangement and ras mutations in gastric carcinogenesis in ferrets. Carcinogenesis.
Smith J.L., Wishnok J.S., Deen W.M. 1993. Distribution and excretion kinetics of methylamines in rats. Carcinogenesis.
Smith J.L., Wishnok J.S., Deen W.M. 1993. Elimination pathways and metabolism of methylamine precursors of N-nitrosodimethylamine in rats. Carcinogenesis.
Fox J.G., Blanco M., Murphy J.C., Taylor N.S., Lee A., Kabok Z., Pappo J. 1993. Local and systemic immune response in murine Helicobacter felis active chronic gastritis. PubMed: Infect Immun. 1993 Jun;61(6):2309-15.
Fox J.G., Blanco M., Polidoro D., Yan L-L., Dewhirst F.E., Paster B.J. 1993. Role of gastric pH in isolation of H. mustelae from the feces of ferrets. PubMed: Gastroenterology. 1993 Jan;104(1):86-92.
Pufahl R.A., Marletta M.A. 1993 Oxidation of NG-hydroxy-L-arginine by nitric oxide synthase: evidence for the involvement of the heme in catalysis. PubMed
Marletta M.A. 1993. Nitric oxide synthase structure and mechanism. PubMed
Hevel J.M., Marletta M.A. 1993. Macrophage nitric oxide synthase: tetrahydrobiopterin decreases the NADPH stoichiometry. PubMed
Castillo L., deRojas-Walker T.C., Chapman T.E, Vogt J., Tannenbaum S.R., Young V.R. 1993. Splanchnic metabolism of dietary arginine in relation to nitric oxide synthesis in normal adult man. Proc. Natl. Acad. Sci., 90, 193-197.
Otto G., Rosenblad W., Fox J.G. 1993. Practical venipuncture techniques for the ferret.PubMed: Lab Anim. Jan;27(1):26-9.
Tannenbaum S.R., Tamir S., deRojas-Walker T., Wishnok J.S. 1993. DNA damage and cytotoxicity by nitric oxide. Proceedings of the ACS Symposium on N-nitroso compounds, Washington D.C., 1992
Esumi H., Tannenbaum S.R. 1993. US- Japan Cooperative Cancer Research Program: Seminar on 'Nitric Oxide Synthase and Carcinogenesis,' January 19 and 20, 1993. Cancer Res., 54, 297-301.
Fox J.G., Wishnok J.S., Murphy J.C., Tannenbaum S.R., Correa P. 1993. MNNG-Induced gastric carcinoma in ferrets infected with Helicobacter mustelea. Carcinogenesis, 14(9), 1957-1961.
Lewis R.S., Deen W.M., Tannenbaum S.R., Wishnok J.S. 1993. Membrane mass spectrometer inlet for quantitation of nitric oxide. J. Biol. Mass Spectrometry, 22, 45-52.
Nunoshiba T., deRojas-Walker T.C., Wishnok J.S., Tannenbaum S.R., Demple B. 1993. Activation by nitric oxide of an oxidative stress response that defends Escherichia coli against activated macrophages. Proc. Natl. Acad. Sci., 90, 9993-9997.
Tamir S., Lewis R.S, deRojas-Walker T.C., Deen W.M., Wishnok J.S., Tannenbaum S.R. 1993. The Influence of Delivery Rate on the Chemistry and Biological Effects of Nitric Oxide. Chem. Res. Toxicol., 6, 895-899.
Wishnok J.S., Tannenbaum S.R., Stillwell W.G, Glogowski J.G., Leaf C.D. 1993. Urinary markers for exposures to alkylating or nitrosating agents. Environ. Health Perspectives, 99, 155-159.
1992
Hevel J.M., Marletta M.A. 1992. Macrophage nitric oxide synthase: relationship between enzyme-bound tetrahydrobiopterin and synthase activity. PubMed
Pufahl R.A., Najappan P.G., Woodard R.W., Marletta M.A. 1992. Mechanistic probes of N-hydroxylation of L-arginine by the inducible nitric oxide synthase from murine macrophages.PubMed
Wishnok J.S. 1992. Environmental Carcinogens: Monitoring in vivo using GC/MS. PubMed-Link: Anal Chem. 1992 Dec 1;64(23):1126A-1135A.
White K.A., Marletta M.A. 1992. Nitric oxide synthase in a cytochrome P-450 type hemoprotein. PubMed
Lee A., Phillips M.W., O'Rourke J.L., Paster B.J., Dewhirst F.E., Fraser G.J., Fox J.G., Sly L.I., Romaniuk P.J., Trust T.J. 1992. Helicobacter muridarum sp. nov., a microaerophilic helical bacterium with a novel ultrastructure isolated from the intestinal mucosa of rodents.PubMed: Int J Syst Bacteriol. Jan;42(1):27-36.
Taylor N.S., Hasubski A.T., Fox J.G., Lee A. 1992. Haemagglutination profiles of Helicobacter species that cause gastritis in man and animals.PubMed: J Med Microbiol. Nov;37(5):299-303.
O'Rourke J., Lee A., Fox J.G. 1992. An ultrastructural study of Helicobacter mustelae and evidence of a specific associated with gastric mucosa. PubMed: J Med Microbiol. 1992 Jun;36(6):420-7.
O'Rourke J., Lee A., Fox J.G. 1992. Helicobacter infection in animals: a clue to the role of adhesion in the pathogenesis of gastroduodenal disease. Eur. J. Gastroenteral Hepatol, 4, S31-S37.
Olken N.M., Marletta M.A. 1992. NG-allyl- and NG-cyclopropyl-L-arginine: two novel inhibitors of macrophage nitric oxide synthase. PubMed
Brown N.K., Nguyen T.T., Taghizadeh K., Wishnok J.S., Tannenbaum S.R. 1992. Mutagenic decomposition products of nitrosated 4-chloroindole. Chem. Res. Toxicol., 5, 797-801.
Nguyen T., Brunson D., Crespi C.L., Penman B.W., Wishnok J.S., Tannenbaum S.R. 1992. DNA damage and mutation in human cells exposed to nitric oxide in vitro. Proc. Natl. Acad. Sci., 89, 3030-3034.
Fox J.G., Paster B.J., Dewhirst F.E., Taylor N.S., Yan L.L., Macuch P.J., Chmura L.M. 1992. Helicobacter mustelae isolation from feces of ferrets: evidence to support fecal-oral transmission of a gastric Helicobacter.PubMed: Infect Immun. 1992 Feb;60(2):606-11.
Tannenbaum S.R., Wishnok J.S. 1992. Deamination of nucleic acids by nitric oxide. In: Nitroso Compounds: Biological Mechanisms, Exposures and cancer etiology. I.K. O'Neill and H. bartsch eds., IARC Technical report No. 11, international Agency for Research on Cancer, Lyon (1992)
Tannenbaum S.R., Wishnok J.S. 1992. Genotoxicity of nitric oxide via nitrosative deamination of bases in DNA. IN: Biology of Nitric Oxide, pp. 206-208.
1991
Hevel J.M., White K.A., Marletta M.A. 1991. Purifacation of the inducible murine macrophage nitric oxide synthase. Identifactaion as a flavoprotein. PubMed
Lee A., Fox J.G., Otto G., Dick E.H., Krakowka S. 1991. Transmission of Helicobacter spp. A challenge to the dogma of faecal-oral spread. PubMed: Epidemiol Infect. Aug;107(1):99-109.
Shultz P.J., Tayeh M.A., Marletta M.A., Raij L. 1991. Synthesis and action of nitrix oxide in rat glomerular mesangial cells. PubMed
Mulligan M.S., Hevel J.M., Marletta M.A., Ward P.A. 1991. Tissue injury cause by deposition of immune complexes is L-arginine dependent. PubMed
Morgan D.R., Fox J.G. Leunk R.D. 1991. Comparison of isolates of Helicobacter pylori and H. mustelae.PubMed: J Clin Microbiol. Feb;29(2):395-7.
Dunn B.E., Sung C.C., Taylor N.S., Fox J.G. 1991. Purifacation and characterization of H. Mustelae urease. PubMed:Infect Immun. 1991 Sep;59(9):3343-5.
Olken N.M., Resche K.M., Richards M.K., Marletta M.A. 1991. Inactivation of macrophage nitric oxide synthase activity by NG-methyl-L-arginine. PubMed
Smith D.J., Dumphy M.J., Strang L.N., Goble D.D., Marletta M.A. 1991. The influence of wound healing on urinary nitrate levels in rats. Wounds, 3, 50-58.
Marletta M.A. 1991. Nitric oxide, nitrovasodilators, and L-arginine-- an unusual relationship. PubMed
Leaf C.D., Wishnok J.S., Tannenbaum S.R. 1991. Endogenous incorporation of nitric oxide from L-arginine into N-nitrosomorpholine stimulated by Escherichia coli lipopolysaccharide in the rat. Carcinogenesis, 12, 537-539.
Stillwell W.G., Glogowski J., Xu H-X., Wishnok J.S., Zavala D., Montes G., Correa P., Tannenbaum S.R. 1991. Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine, and 7-methylguanine in a Colombian population at high risk for stomach cancer. Cancer Res., 51, 190-194.
Stillwell W.G., Yu H-X., Glogowski J., Wishnok J.S., Tannenbaum S.R., Correa P. 1991. Comparison of urinary nitrate, N-nitrosoproline, 7-methylguanine, and 3-methyladenine in a human population at risk for gastric cancer. IN: Relevance to Human Cancer of N-nitroso Compounds, Tobacco Smoke and Mycotoxins, pp. 83-87.
Stillwell W.G., Glogowski J., Xu H-X., Wishnok J.S., Zavala D., Montes G., Correa P., Tannenbaum S.R. 1991. Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine, and 7-methylguanine in a Colombian population at high risk for stomach cancer. PubMed: Cancer Res. 1991 Jan 1;51(1):190-4.
Paster B.J., Lee A., Fox J.G., Dewhirst F.E., Tordoff L.A., Fraser G.J., O'Rourke J.L., Taylor N.S``., Ferrero R. 1991. Phylogeny of Helicobacter felis sp. nov., Helicobacter mustelae, and related bacteria. PubMed-Link: Int J Syst Bacteriol. Jan;41(1):31-8.
Fox J.G., Otto G., Lee A., et al. 1991. Helicobacter felis gastritis in gnotobiotic rats: an animal model of H. pylori gastritis.PubMed:Infect Immun. 1991 Mar;59(3):785-91.
Fox J.G., Otto G., Taylor N.S., et al. 1991. H. mustelae-induced gastritis and elevated gastric pH in the ferret (Mustela putorius furo.)PubMed: Infect Immun. 1991 Jun;59(6):1875-80
Fox J.G., Otto G., Murphy J.C., et al. 1991. Gastric colonization of the ferret with Helicobacter species: natural and experimental infections.PubMed: Rev Infect Dis. 1991 Jul-Aug;13 Suppl 8:S671-80.
Vargas M., Lee A., Fox J., Cave D. 1991. Inhibition of acid secretion from parietal cells by non-human-infecting Helicobacter species: a factor in colonization of gastric mucosa?PubMed: Infect Immun. Oct;59(10):3694-9.
Tannenbaum S.R., Wishnok J.S., Leaf C.D. 1991. Inhibition of nitrosamine formation by ascorbic acid. American Journal of Clinical Nutrition Supplement, 53, S247-S250.
1990
Lee A., Fox J.G, Otto G., Murphy J.C. 1990. A small animal model of human Helicobacter pylori active chronic gastritis. PubMed: Gastroenterology. Nov;99(5):1315-23.
Fox J.G., Correa P., Taylor N.S., et al. 1990. H. mustelae associated gastritis in ferrets: an animal model of Helicobacter pylori gastritis in humans.PubMed: Gastroenterology. 1990 Aug;99(2):352-61.
Otto G., Fox J.G., Wu P-Y., Taylor N.S. 1990. Eradication of Helicobacter mustelae from the ferret stomach: an animal model of Helicobacter (campylobacter) pylori chemotherapy. PubMed: Antimicrob Agents Chemother. Jun;34(6):1232-6.
Marletta M.A., Tayeh M.A., Hevel J.M. 1990. Unraveling the biological significance of nitric oxide. PubMed
Fox J.G., Paster B.J., Lee A., et al. 1990. Genus and species specific probes for identifacation of Helicobacter sp. from a man and animals. III Workshop Gastroduodenal Pathology and Campybacter (Helicobacter) Pylori, Toledo, Spain. Rev. Esp. Inf. Dig. (suppl 1), 78, 30-31
Palley L.S., Marini R.P., Rosenblad W.D., Fox J.G., Rosenbald W.D. 1990. A technique for femoral bone marrow collection in the ferret.PubMed: Lab Anim Sci. 1990 Nov;40(6):654-5.
Correa P., Haenszel W., Cuello C., Zavalla D., Fontham E., Zarama G., Tannenbaum S.R., Cozallos T., Ruiz B. 1990. Gastric precancerous process in a high risk population: cross-sectional studies. Cancer Res., 50, 4731-4736.
Correa P., Haenszel W., Cuello C., Zavalla D., Fontham E., Zarama G., Tannenbaum S.R., Cozallos T., Ruiz B. 1990. Gastric precancerous process in a high risk population: cohort follow-up. Cancer Res., 50, 4737-4740.
McMahon G., Davis E.F., Huber J., Kim Y. Wogan G.N. 1990. Characterization of c-Ki-ras and N-ras oncogenes in aflatoxin B1-induced rat liver tumors. PubMed: Proc Natl Acad Sci U S A. Feb;87(3):1104-8.
Zeisel S.H. 1990. Biological consequences of choline deficiency. In: Choline Metabolism and Brain Function, Nutrition, and the Brain, Vol. 8, (R. Wurtman and J. Wurtman, eds.), Raven Press, NY.
Prevost V., Shuker D.E.G., Bartsch H., Pastorelli R., Stillwell W.G., Trudel L.J., Tannenbaum S.R. 1990. The determination of urinary 3-methyladenine by immunoaffinity chromatography-monoclonal antibody-based ELISA: use in human biomonitoring studies. PubMed: Carcinogenesis. 1990 Oct;11(10):1747-51.
Cabot E.B., Fox J.G. 1990. Bile reflux and the gastric mucosa: an experimental ferret model. PubMed: J Invest Surg. 1990;3(2):177-89.
Sylvina T.J., Berman N.G., Fox J.G. 1990. Effects of Yohimbine on Bradycardia and Duration of Recumbency in Ketamine/Xylazine Anesthetized ferrets. PubMed
Leaf C.D., Wishnok J.S., Hurley J.P., Rosenblad W.D., Fox J.G., Tannenbaum S.R. 1990. Nitrate biosynthesis in rats, ferrets and humans. Precursor studies with L-arginine. Carcinogenesis, 11, 855-858.
1989
Marletta M.A, 1989. Nitric oxide: biosynthesis and biological significance. PubMed
Ryden E.B., Licht W.R., Cabot E.B. Fox J.G. 1989. Gastric nitrate processing in the surgically altered maximal and minimal bile relux ferret model.PubMed: Carcinogenesis. 1990 Mar;11(3):405-9.
Tayeh M.A., Marletta M.A. 1989. Macrophage oxidation of L-arginine to nitric oxide, nitrite and nitrate. Tetrahydrobiopterin is required as a cofactor.PubMed: J Biol Chem. 1989 Nov 25;264(33):19654-8
Fox J.G., Lee A. 1989. Gastric campylobacter-like organisms: Their role in gastric disease of labratory animals. PubMed:Lab Anim Sci. 1989 Nov;39(6):543-53.
Fox J.G., Chilvers T., Goodwin S., Taylor N.S., Edmonds P., Sly L.I., Brenner D.J. 1989. Campylobacter mustelae, a new species resulting from the elevation of Campylobacter pylori subsp. mustelae to species status. Int. J. System. Bacteriol., 39, 301-303.
Kosaka H., Wishnok J.S., Miwa M., Leaf C.D, Tannenbaum S.R. 1989. Nitrosation by stimulated macrophages. Inhibitors, enhancers and substrate. Carcinogenesis, 10, 563-566.
Leaf C.D., Wishnok J.S., Tannenbaum S.R. 1989. Nitric oxide: the dark side. IN: Nitric Oxide from L-Arginine: A Bioregulatory System, pp. 291-300.
Leaf C.D., Wishnok J.S., Tannenbaum S.R. 1989. Mechanisms of endogenous nitrosation. Cancer Surveys, 8, 629-637.
Leaf C.D., Wishnok J.S., Tannenbaum S.R. 1989. L-arginine is a precursor for nitrate biosynthesis in humans. Biochem. Biophys. Res. Comm., 163, 1032-1037.
Gan L.S., Wishnok J.S. Tannenbaum S.R., Fox F.G. 1989. Quanitation of methylated hemoglobin via hydrolysis of mythyl esters to yield methanol. PubMed:Anal Biochem. Jun;179(2):326-31.
Tannenbaum S.R. 1989. Preventive action of vitamin C on nitrosamine formation. Int. J. Vitamin. Nutr., Supple., 30, 109-113.
Zeisel S.H., Gettner S., Youssef M. 1989. Formation of aliphatic amine precursors of dimethylnitrosamine after oral administration of choline and choline analogs in the rat. PubMed-Link: Fd. Chem. Toxic., 27(1), 31-34.
van den Brandt P.A., Willett W.C., Tannenbaum S.R. 1989. Assessment of dietary nitrate intake by a self-administered questionnaire and by overnight urinary measurement. Int. J. Epidem., 18, 852-857.
Stillwell W.G., Xu H-X., Adkins J.A., Wishnok J.S., Tannenbaum S.R. 1989. Analysis of methylated and oxidized puries in urine by capillary gas chromatography-mass spectrometry. PubMed-Link:Chem Res Toxicol. 1989 Mar-Apr;2(2):94-9.
Stillwell W.G., Xu H-X., Glogowski J., Wishnok J.S., Tannenbaum S.R., Correa P. 1989. Compairson of urinary nitrate, N-nitrosoproline, 7-methylguanine, and 3-methyladenine in a human population at risk for gastric cancer. PubMed
1988
Fox J.G., Cabot E.B., Taylor N.S., Laraway R. 1988. Gastric Colonization by Campylobacter pylori subsp. mustelae in ferrets. PubMed: Infect Immun. Nov;56(11):2994-6
Marletta M.A., Yoon P.S., Iyengar R., Leaf C.D. Wishnok J.S. 1988. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. PubMed-Link
Marletta M.A. 1988. Mammalian Synthesis of nitrite, nitrate, nitric oxide, and N-nitrosating agents. PubMed
Geribaldi B.A., Pecquet-Goad M.E., Fox J.G., Sylvania T.J., Murray R. 1988. Serum cortisol radioimmunoassay values in the normal ferret and response to ACTH stimulation and dexamethasone suppression tests.PubMed
Geribaldi B.A., Pecquet-Goad M.E., Fox J.G., Murray R. 1988. Serum thyroxine and triiodothyronine radio immunoassay values in the normal ferret. PubMed
Mesina J.E., Sylvania T.J., Hotaling L.C., Pecquet-Goad M.E., Fox J.G. 1988 A simple technique for chronic jugular catheterization in ferrets. PubMed
Licht W.R., Deen W.M. 1988. Theoretical model for predicting rates of nitrosamine and nitrosamide formation in the human stomach. PubMed: Carcinogenesis. Dec;9(12):2227-37.
Licht W.R., Fox J.G. Deen W.M. 1988. Effects of ascorbic acid and thiocyanate on nitrosation of proline in the dog stomach. PubMed:Carcinogenesis. Mar;9(3):373-7.
Licht W.R., Tannenbaum S.R., Deen W.M. 1988. Use of ascorbic acid to inhibit nitrosation: kinetic and mass transfer considerations for an in vitro system. Carcinogenesis, 9, 365-372.
Marletta M.A., Poksyn S.Y., Iyengar R. Leaf C.D., Wishnok J.S. 1988. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate.PubMed:Biochemistry. 1988 Nov 29;27(24):8706-11.
Ralt D., Wishnok J.S., Fitts R., Tannenbaum S.R. 1988. Bacterial catalysis of nitrosation: involvement of the nar operon of Escherichia coli. J. Bacteriology, 170, 359-364.
Tannenbaum S.R. 1988. Mechanisms of endogenous nitrosation. IN: Models and Mechanisms in Chemical Carcinogenesis, pp. 629-637.
1987
Bonney G.E., Elston R.C., Correa P., Tannenbaum S.R., Haenszel W., Zavala D.E., Fontham E., Zarama G., Gordillo G., Cuello C. 1987. Genetic etiology of gastric carcinoma: II. Segregation analysis of gastric pH, nitrate, and nitrite. Genetic Epidemiology, 4, 103-114.
Miwa M., Stuehr D.J., Marletta M.A., Wishnok J.S., Tannenbaum S.R. 1987. Nitrosation of amines by stimulated macrophages. Carcinogenesis, 8, 955-958.
Miwa M., Stuehr D.J., Marletta M.A., Wishnok J.S., Tannenbaum S.R. 1987. N-nitrosamine formation by macrophages. IN: The Relevance of N-Nitroso Compounds to Human Cancer Exposures and Mechanisms, pp. 340-344.
Stuehr D.J., Marletta M.A. 1987. Synthesis of nitrite and nitrate in murine macrophage cell lines. PubMed:Cancer Res. 1987 Nov 1;47(21):5590-4.
Stuehr D.J., Marletta M.A. 1987. Further Studies on murine microphage synthesis of nitrite and nitrate. PubMed
Tannenbaum S.R., Wishnok J.S. 1987. Inhibition of nitrosamine formation by ascorbic acid. IN: Third Conference on Vitamin C, Annals of the New York Academy of Sciences, Vol 498, pp. 354-363.
Tannembaum S.R. 1987. Endogenous formation of N-nitroso compounds: a current perspective. IN: The Relevance of N-Nitroso Compounds to Human Cancer Exposures and Mechanisms, pp. 292-295.
Wishnok J.S., Tannenbaum S.R., Fox J.G., Mesina J.E., Hotaling L.C. 1987. The ferret as a model for endogenous synthesis and metabolism of N-nitrosamines. IN: The Relevance of N-Nitroso Compounds to Human Cancer Exposures and Mechanisms, pp. 135-137.
Zeisel S.H. 1987. Diet and brain function: Available information and misinformation. In: Pediatric Mutrition: Theory and Practice, R.J. Grand, J.L. Sulphen and W.H. Dietz, Eds., Butterworths: Boston, pp 801-808.
Wogan G.N., Tannenbaum S.R. 1987. Biological monitoring of environmental toxic chemicals. IN: Toxic Chemicals, Health and the Environment, Chapter 7, pp. 142-169.
Iyengar R., Stuehr D.J., Marletta M.A. 1987. Microphage synthesis of nitrite, nitrate, and N-nitrosamines: Precursors and role of the respiratory burst. PubMed: Proc Natl Acad Sci U S A. Sep;84(18):6369-73.
Newberne P.M., Charnley G., Adams K., Cantor M., Suphakarn V., Roth D., Schrager T.F. 1987. Gastric carcinogenesis: A model for the identification of risc factors. PubMed
1986
Buchi G., Lee G.C.M., Yang D., Tannenbaum S.R. 1986. Direct acting, highly mutagenic, alpha-hydroxy N-nitrosamines from 4-chloroindoles. J. Amer. Chem. Society, 108, 4115-4119.
Fox J.G., Edrise B.M., Cabot E.B., Beaucage C., Murphy J.C., Prostak K.S. 1986. Campylobacter-like organisms isolated from gastic mucosa of ferrets.PubMed
Fontham, E., D. Zavala, P. Correa, E. Rodriguez, F. Hunter, W. Haenszel, and S.R. Tannenbaum. 1986. Diet and chronic atrophic gastritis: a case-control study. J. Natl. Canc. Inst., 76, 621-627.
Licht W.R., Schultz D.S., Fox J.G., Tannenbaum S.R., Deen W.M. 1986. Mechanisms for nitrite loss from the stomach. Carcinogenesis, 7, 1681-1687.
Zeisel S.H. 1986. "Vitamin-like" molecules: A. Choline. In: M.E. Shils and V.R. Young, Eds., Modern Nutrition in Health and Disease. Lea & Febiger, PP. 1-13.
Sheard N.F., Zeisel S.H. 1986. An in vitro study of choline uptake by intestine from neonatal and adult rats.PubMed-Link: Pediatr Res. 1986 Aug;20(8):768-72.
Zeisel S.H., DaCosta K-A. 1986. Increase in human exposure to methylamine precursors of N-nitrosamines after eating fish. PubMed
Zeisel S.H., DaCosta K-A., Edrise B.M., Fox J.G. 1986. Transport of dimethylamine, a precursor of nitrosodimethylamine, into the stomach of ferret and dog. Carsinogenesis, 7, 775-778.
Normington K.W., Baker I., Molina M., Wishnok J.S., Tannenbaum S.R., Song P. 1986. Characterization of a nitrite scavenger, 3-hydroxy-2-pyranone, from Chinese wild plum juice. J. Agr. Food Chem., 34, 3244-3246.
Tannenbaum S.R.. 1986. Diet and exposure to N-nitroso compounds. IN: Diet, Nutrition, and Cancer, Y. Hayashi et al., (eds.), pp. 67-75.
1985
Busby W.F. Jr., Shuker D.E.G., Charnley G., Newberne P.M., Tannenbaum S.R., Wogan G.N. 1985. Carcinogenicity in rats of the nitrosated bile acid conjugates N-nitrosoglycocholic acid and N-nitrosotaurocholic acid. Cancer Res., 45, 1367-1371.
Charnley G., Tannenbaum S.R. 1985. Flow cytometric analysis of the effect of sodium chloride on gastric cancer risk in the rat. Cancer Res., 45, 5608-5616.
Zeisel S.H., DaCosta K-A., Fox J.G. 1985. Endogenous formation of dimethylamine. PubMed
Zeisel S.H., DaCosta K-A., LaMont J.T. 1985. Mono-, di- and trimethylamine in human gastric fluid: potential substrates for nitrosodimethylamine formation. Carcinogenesis, 9, 179-181.
Stuehr D.J., Marletta M.A. 1985. Mammalian nitrate biosynthesis: Mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. PubMed
Stuehr D.J., Marletta M.A. 1985. Superoxide-promoted odixation reactions in murine macrophages by BCG infection, lymphokines, or interferon-. J. of aniline and N-methylaniline in dimethylsulfoxide. J. Organic Chem.Immunol., 193, 518-525
Stuehr D.J., Marletta M.A. 1985. Superoxide-promoted oxidation reactions of aniline N-methylaniline in dimethylsulfoxide. J. Organic Chem.
Kim S.H., Wishnok J.S., Tannenbaum S.R. 1985. Formation of N-nitrosodimethylamine in Korean seafood sauces. J. Agr. Food Chem., 33, 17-19.
Schultz, D.S., Deen W.M., Karel S.F., Wagner D.A., Tannenbaum S.R. 1985. Pharmacokinetics of nitrate in humans: role of gastrointestinal absorption and metabolism. Carcinogenesis, 6, 847-852.
Tannenbaum S.R., Bishop W., Yu M.C., Henderson B.E. 1985. Attempts to isolate N-nitroso compounds from Chinese-style salted fish. N.C.I. Monograph, 69, 209-211.
Tannenbaum S.R., Correa P. 1985. Nitrage and gastric cancer risk. Nature, 317, 675-676.
Zeisel S.H., DeCosta K-A., Fox J.G. 1985. Endogenous formation of dimethylamine. Biochem. J.
Wagner D.A., Tannenbaum S.R. 1985. In vivo formation of N-nitroso compounds. Food Technology, 39, 89-90.
Wagner D.A., Shuker D.E.G., Bilmazes C., Obiedzinski M., Baker I., Young V.R., Tannenbaum S.R. 1985. Effect of vitamins C and E on endogenous synthesis of N-nitrosamino acids in humans: precursor-product studies with [15N]nitrate. Cancer Res., 45, 6519-6522.
Wagner D.A., Moldawer L.L., Pomposelli J.J., Tannenbaum S.R., Young V.R. 1985. Nitrate biosynthesis in the rat. Precursor-product relationships with respect to ammonia. Biochem. J., 232, 547-551.
1984
Dabora R., Molina M., Ng M., Wishnok J.S., Tannenbaum S.R. 1984. Nitrosation by alkyl nitrites: Catalysis by inorganic salts. IN: N-Nitroso Compounds: Occurence, Biological Effects and Relevance to Human Cancer, pp. 311-316.
Song P., Lin Z., Yinzeng Y., Lan D., Tannenbaum S.R., Wishnok J.S. 1984. The blocking effects of Chinese Actinidia sinensis juice on N-nitrosamine formation in vitro and in vivo. IN: N-Nitroso Compounds: Occurence, Biological Effects and Relevance to Human Cancer, pp. 231-236.
Song P., Tannenbaum S.R. 1984. The effects of Actinidia Chinensis Planch in the prevention of cancer. 1. The blocking effect of fruit juice on the nitrosation of morpholine-nitrite. Acta Nutrimenta Sinica, 6, 109-114.
Tomera J.F., Skipper P.L., Wishnok J.S., Tannenbaum S.R., Brunengraber H. 1984. Inhibition of N-nitrosodimethylamine metabolism by ethanol and other inhibitors in the isolated perfused rat liver. Carcinogenesis, 5, 113-116.
Wagner D.A., Shuker D.E.G., Bilmazes C., Obiedzinski M., Young V.R., Tannenbaum S.R. 1984. Modulation of endogenous synthesis of N-nitrosamino acids in humans. IN: N-Nitroso Compounds: Occurence, Biological Effects and Relevance to Human Cancer, pp. 223-230.
Wagner D.A., Schultz D.S., Deen D.M., Young V.R., Tannenbaum S.R. 1984. Mammalian nitrate biochemistry: metabolism and endogenous synthesis. IN: N-Nitroso Compounds: Occurence, Biological Effects and Relevance to Human Cancer, pp. 247-254.
Yang D., Tannenbaum S.R., Buchi G., Lee G.C.M. 1984. 4-Chloro-6-methoxyindole is the precursor of a potent mutagen (4-chloro-6-methoxy-2-hydroxy-1-nitroso-indolin-3-one oxime) that forms during nitrosation of the fava bean (Vicia faba). Carcinogenesis, 5, 1219-1224.
1983
Shuker D.E.G., Tannenbaum S.R. 1983. Determination of nonvolatile N-nitroso compounds in biological fluids by liquid chromatography with postcolumn photohydrolysis detection. Anal. Chem., 55, 2152-2155.
Skipper P.L., Tomera J.F., Wishnok J.S., Brunengraber H., Tannenbaum S.R. 1983. Pharmacokinetic model for N-nitrosodimethylamine based on Michaelis-Menten constants determined with the isolated perfused rat liver. Cancer Res., 43, 4786-4790.
Tannenbaum S.R. 1983. N-nitroso compounds: a perspective on human exposure. Lancet, 629-632.
Wagner D.A., Schultz D.S., Deen W.M., Young V.R., Tannenbaum S.R. 1983. Metabolic fate of an oral dose of 15N-labeled nitrate in humans: effect of diet supplementation with ascorbic acid. Cancer Res., 43(4), 1921-1925.
Wagner D.A., Young V.R., Tannenbaum S.R. 1983. Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment. Proc. Natl. Acad. Sci., 80, 4518-4521.
Zeisel S.H., Wishnok J.S., Blusztajn J.K. 1983. Formation of methylamines from ingested choline and lecithin.PubMed-Link: J. Pharmacol. Exper. Therap, 225, 320-324.
1982
Charnley G., Tannenbaum S.R., Correa P. 1982. Gastric cancer: an etiologic model. IN: Nitrosamines in Human Cancer, Banbury Report No. 12, pp. 503-522.
Correa P., Haenszel W., Tannenbaum S.R. 1982. Epidemiology of gastric carcinoma: review and future prospects. N.C.I. Monograph No. 62, 129-134.
Green L.C., Tannenbaum S.R., Fox J.G. 1982. Nitrate in human and canine milk. Letter to the Editor. N.E.J. Med., 306, 1367.
Green L.C., Ralt D., Tannenbaum S.R. 1982. Nitrate, nitrite and N-nitroso compounds: Biochemistry, metabolism, toxicity and carcinogenicity. IN: Human Nutrition: Current Issues and Controversies, pp. 87-140.
Green L.C., Tannenbaum S.R. 1982. Nitrite and nitrate in food. Nutrition & the M.D., Vol VIII, pp. 1-6.
Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnok J.S., Tannenbaum S.R. 1982. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal. Biochem., 126, 131-138.
Kim Y.K., Tannenbaum S.R, Wishnok J.S. 1982. Effects of ascorbis acid on the nitrosation of dialkylamines. IN: Ascorbic Acid: Chemistry, Metabolism and Uses, pp. 571-585.
Lintas C., Clark A., Fox J.G., Tannenbaum S.R., Newberne P.M. 1982. In vivo stability of nitrite and nitrosamine formation in the dog stomach: effect of nitrite and amine concentration and of ascorbic acid. Carcinogenesis, 3, 161-165.
Piacek-Llanes B.G., Tannebaum S.R. 1982. Formation of an activated N-nitroso compound in nitrite-treated fava beans (Vicia faba). Carcinogenesis, 3, 1379-1384.
Piacek-Llanes B.G., Shuker D.E.G., Tannebaum S.R. 1982. N-nitrosamides of natural origin. IN: N-Nitroso Compounds: Occurence and Biological Effects, pp. 123-130.
Song P., Shuker D.E.G., Bishop W.W., Falchuk K.R., Tannenbaum S.R., Thilly W.G. 1982. Mutagenicity of N-Nitroso bile acid conjugates in Salmonella typhimurium and diploid human lymphoblasts. Cancer Res., 42, 2601-2604.
Tannenbaum S.R., Correa P., Newberne P.M., Fox J.G. 1982. Endogenous formation of N-nitroso compounds and gastric cancer. IN: Environmental Mutagens and Carcinogens, pp. 565-569.
Wagner D.A., Tannenbaum S.R. 1982. Enhancement of nitrate biosynthesis by Escherichia coli lypopolysaccharide. IN: Nitrosamines and Human Cancer, pp. 437-441.
Wagner D.A., Shuker D.E.G., Hasic G., Tannenbaum S.R. 1982. Endogenous nitrosoproline synthesis in humans. IN: Nitrosamines and Human Cancer, pp. 319-323.
Puju S., Shuker D.E., Bishop W.W., Falchuk K.R., Tannenbaum S.R., Thilly W.G. 1982. Mutagenicity of N-Nitroso bile acid conjugates in Salmonella typhimurium and diploid human lymphoblasts. PubMed
1981
Correa P., Tannenbaum S.R. 1981. The microecology of gastric cancer. IN: N-Nitroso Compounds, Advances in Chemistry Symposium Series No. 174, Vol. 22, pp. 319-329.
Green L.C., K. Ruiz de Luzuriaga, D.A. Wagner, W. Rand, N. Istfan, V.R. Young, and S.R. Tannenbaum. 1981. Nitrate biosynthesis in man. Proc. Natl. Acad. Sci., 78, 7764-7768.
Green L., Tannenbaum S.R. 1981. Nitrate synthesis in the germfree and conventional rat. Science, 212, 56-58.
Hansen T.J., Tannenbaum S.R., Archer M.C. 1981. Identification of a nonenylnitrolic acid in corn treated with nitrous acid. J. Agr. Food Chem., 29, 1008-1011.
Kraft P.L., Skipper P.L., Charnley G., Tannenbaum S.R. 1981. Urinary excretion of dimethylnitrosamine: a quantitative relationship between dose and urinary excretion. Carcinogenesis, 2, 609-612.
Ralt D., Gomez R., Tannenbaum S.R. 1981. Conversation of acetohydroxamate and hydroxylamine to nitrite by intestinal microorganisms. Eur. J. Appl. Microbiol. Biotech., 12, 226-230.
Ralt D., Tannenbaum S.R. 1981. The role of bacteria in nitrosamine formation. IN: N-Nitroso Compounds. ACS Symposium Series No. 174, pp. 157-164.
Shuker D.E.G., Tannenbaum S.R., Wishnok J.S. 1981. N-Nitroso bile acid conjugates 1. Synthesis chemical reactivity and mutagenic activity. J. Org. Chem., 46, 2092-2096.
Tannenbaum S.R.. 1981. Endogenous formation of N-nitroso compounds. IN: Gastrointestinal Cancer: Endogenous Factors, Banbury Report No. 7, pp. 269-273.
Tannenbaum S.R., Green L.C. 1981. Metabolism of nitrate. IN: Gastrointestinal Cancer: Endogenous Factors, Banbury Report No. 7, pp. 331-341.
Tannenbaum S.R., Moran D. 1981. Epidemiological studies of nitrate, nitrite and gastric cancer. IN: Safety Evaluation of Nitrosatable Drugs & Chemicals, pp. 234-244.
Tannenbaum S.R., Moran D. Falchuk K.R., Correa P., Cuello C. 1981. Nitrite stability and nitrosation potential in human gastric juice. Cancer Lett., 14, 131-136.
1980
Archer M.C., Hansen T.J., Tannenbaum S.R. 1980. Compounds formed by treatment of corn (Zea mays) with nitrous acid. IARC Scientific Publication No. 31, pp. 305-318.
Kim Y.K., Tannenbaum S.R., Wishnok J.S. 1980. Nitrosation of dialkylamines in the presence of bile acid conjugates. IARC Scientific Publication No. 31, pp. 207-214.
Kraft P.L., Skipper P.L, Tannenbaum S.R. 1980. In vivo metabolism and whole-blood clearance of n-nitrosomethylbenzylamine in the rat. Cancer Res., 40, 2740-2742.
Kraft P.L., Tannenbaum S.R. 1980. Distribution of N-nitrosomethylbenzylamine evaluated by whole-body radioautography and densitometry. Cancer Res., 40, 1921-1927.
Obiedzinski M.W., Wishnok J.S., Tannenbaum S.R. 1980. N-Nitroso compounds from reactions of nitrite with methylamine, Food and Cosmet. Toxicol., 18, 585-589.
Tannenbaum S.R. 1980. Ins and outs of nitrites. The Sciences (January), pp. 7-9.
Tannenbaum S.R. 1980. A model for estimation of human exposure to endogenous N-nitrosodimethylamine. Oncology, 37, 232-235.
Tannenbaum S.R., Green L.C., de Luzuriaga K.R., Gordillo G., Ullman L., Young V.R. 1980. Endogenous carcinogenesis: nitrate, nitrite and N-nitroso compounds. IN: Carcinogenesis: Fundamental Mechanisms and Environmental Effects, pp. 287-296.
Gomez R.F., Tannenbaum S.R., Savoca J., Ralt D., Rockowitz, N. 1980. Heterotrophic nitrifactation by intestinal microorganizms.PubMed
Tannenbaum S.R., Mergens W. 1980. Reaction of nitrite with vitamins C and E. Annals of New York Academy of Sciences, 355, 267-277.
Tannenbaum S.R., Young V.R. 1980. Endogenous nitrite formation in man. J. Environ. Pathol. and Toxicol., 3, 357-368.
Tannenbaum S.R., Young V.R., Green L., Ruiz de Luzuriaga P. 1980. Intestinal formation of nitrite and N-nitroso compounds. Proceedings of the Sixth Meeting on Analysis and Formation of N-nitroso Compounds, IARC Scientific Publication No. 31, pp. 281-289.
1979
Correa P., C. Cuello, G. Gordillo, G. Zarama, J. Lopez, W. Haenszel, and S.R. Tannenbaum. 1979. The gastric microenvironment in populations at high risk to stomach cancer. J. Natl. Canc. Inst., 53, 167-170.
Hansen T.J., Archer M.C., Tannenbaum S.R. 1979. Identification of nitrohexane in corn treated with nitrous acid. J. Agr. Food Chem., 27, 1072-1075.
Hansen T.J., Archer M.C., Tannenbaum S.R. 1979. Characterization of pyrolysis conditions and interference by other compounds in the chemiluminescence detection of nitrosamines. Anal. Chem., 51, 1526-1528.
Mergens W.J., Vane F.M., Tannenbaum,S.R., Green L., Skipper P.L. 1979. In vitro nitrosation of methapyrilene. J. Pharm. Sci., 68, 827-832.
Tannenbaum S.R.. 1979. Endogenous formation of nitrite and N-nitroso compounds. IN: Naturally Occurring Carcinogens-Mutagens and Modulators of Carcinogenesis, pp. 211-220.
Tannenbaum S.R.. 1979. Nitrate and Nitrite: origin in humans. PubMed-Link
Tannenbaum S.R.. 1979. Relative risk assessment of various sources of nitrite. Meat Industry Research Conference, American Meat Institute: Arlington, VA.
Tannenbaum S.R., Moran D., Rand W., Cuello C., Correa P. 1979. Gastric cancer in Colombia. IV. Nitrite and other ions in gastric contents of residents from a high-risk region. J. Natl. Canc. Inst., 62, 9-12.
1978
Baldwin J.E., Scott A., Branz S.E., Tannenbaum S.R., Green L. 1978. Chemical studies on carcinogenic nitrosamines. 1. Hydrolysis of alpha-acetoxynitrosamines. J. Org. Chem., 43, 2427-2431.
Tannenbaum S.R., Archer M.C., Wishnok J.S., Bishop W.W. 1978. Nitrosamine formation in human saliva. J. Natl. Canc. Inst., 60, 251-253.
Tannenbaum S.R., Fett D., Young V.R., Land P.D., Bruce W.R. 1978. Nitrite and nitrate are formed by endogenous synthesis in the human intestine. Science, 200, 1487-1489.
Tannenbaum S.R., Wishnok, J.S. Hovis, and W.W. Bishop. 1978. N-Nitroso compounds from the reaction of primary amines with nitrite and thiocyanate. IN: Environmental Aspects of N-Nitroso Compounds, IARC Scientific Publication No. 19, pp. 155-160.
1977
Hansen T., Iwaoka W., Green L.C., Tannenbaum S.R. 1977. Analysis of N-nitrosoproline in raw bacon. Further evidence that nitrosoproline is not a major precursor of nitrosopyrrolidine. J. Agr. Food Chem., 25, 1423-1426.
Skipper P.L., Tannenbaum S.R., Baldwin J.E., Scott A. 1977. Alkylation by alpha-acetoxy-N-nitrosamines: Models for N-nitrosamine metabolites. Tetrahedron Lett., 49, 4269-4272.
Wishnok J.S., Tannenbaum S.R. 1977. An unknown salivary morpholine metabolite. PubMed-Link
Tannenbaum S.R., Kraft P., Baldwin J., Branz S. 1977. The mutagenicity of methylbenzylnitrosamine and its alpha-acetoxy derivatives. Cancer Lett., 2, 305-310.
Tannenbaum S.R., Archer M.C., Wishnok J.S., Correa P., Cuello C., Haenszel H. 1977. Nitrate and the etiology of gastric cancer. IN: Origins of Human Cancer, pp. 1609-1625.
1976
Archer M.C., Tannenbaum S.R., Wishnok J.S. 1976. Nitrosamine formation in the presence of carbonyl compounds. IN: Environmental N-Nitroso Compounds: Analysis and Formation, IARC Scientific Publication No. 14, pp. 141-145.
Baldwin J.E., Branz S.E., Gomez R.F., Kraft P.L., Sinskey A.J., Tannenbaum S.R. 1976. Chemical activation of nitrosamines into mutagenic agents. Tetrahedron Lett., 5, 333-336.
Cuello C., Correa P, Haenszel W., Gordillo G., Brown C., Archer M.C., Tannenbaum S.R. 1976. Gastric cancer in Colombia. I. Cancer risk and suspect environmental agents. J. Natl. Canc. Inst., 57, 1015-1035.
Green L., Hansen T.J., Iwaoka W.T., Tannenbaum S.R. 1976. Specific detection systems for the chromatographic analysis of nitrosamines. Proc of 2nd International Symposium Nitrite Meat Prod., pp. 145-153.
Hsieh S.T., Kraft P.L., Archer M.C., Tannenbaum S.R. 1976. Reaction of nitrosamines in the Udenfriend system: principal products and biological activity. Mutat. Res., 35, 23-28.
Iwaoka W., Tannenbaum S.R. 1976. Liquid chromatography of N-nitrosoamino acids and their syn and anti conformers.J. Chromatogr., 124, 105-110.
Iwaoka W., Tannenbaum S.R. 1976. Photohydrolytic detection of N-nitroso compounds in high performance liquid chromatography. IN: Environmental N-Nitroso Compounds Analysis and Formation, IARC Scientific Publication No. 14, pp. 51-56.
Tannenbaum S.R. 1976. Relative risk of nitrate and nitrite ingestion. Proc. of the Meat Industry Research Conference, American Meat Institute Foundation: Arlington, VA (March 25).
Tannenbaum S.R., Weisman M., Fett D. 1976. The effect of nitrate intake on nitrite formation in human saliva. Food Cosmet. Toxicol., 14, 549-552.
Tannenbaum S.R. 1976. Nitrates, nitrites, and N-nitroso compounds as environmental hazards: a personal perspective. Proc. of American Cancer Society (March 26-30).
1975
Archer M.C., Tannenbaum S.R., Fan T.Y., Weisman M. 1975. Reaction of nitrite with ascorbate and its relation to nitrosamine formation. Journal of the National Cancer Institute, 54, 1203-1205.
Correa P., Haenszel H., Cuello C., Tannenbaum S.R., Archer M.C. 1975. A model for gastric cancer epidemiology. Lancet (July 12), pp. 58-62.
Moran D.M., Tannenbaum S.R., Archer M.C. 1975. Inhibitor of Clostridium perfringens formed by heating sodium nitrite in a chemically defined medium. Applied Microbiology, 30, 838-843.
Wogan G.N., Tannenbaum S.R. 1975. Environmental N-nitroso compounds: implications for public health. Toxicol. Appl. Pharm., 31, 375-383.
Wogan G.N., Paglialunga S., Archer M.C., Tannenbaum S.R. 1975. Carcinogenicity of nitrosation products of ephedrine, sarcosine, folic acid, and creatinine. Cancer Res., 35, 1981-1984.
1974
Iwaoka W., Weisman M., Tannenbaum S.R. 1974. A solvent partitioning, high speed, liquid chromatographic procedure for the clean up in the analysis of nitrosamines. IN: N-Nitroso compounds in the environment, IARC Scientific Publication No. 9, pp. 32-35.
Tannenbaum S.R., Sinskey A.J., Weisman M., W. Bishop. 1974. Nitrite in human saliva. Its possible relationship to nitrosamine formation. Journal of the National Cancer Institute, 53, 79-84.
1973
Archer M.C., Tannenbaum S.R. 1973. Nitrosation in the environment. Can it occur? Reply to comments. Science, 179, 97.
Fan T.Y., Tannenbaum S.R. 1973. Factors influencing the rate of formation of nitrosomorpholine from morpholine and nitrite: acceleration by thiocyanate and other anions. J. Agric. Food Chem., 21, 237-240.
Fan T.Y., Tannenbaum S.R. 1973. Natural inhibitors of nitrosation reactions: the concept of available nitrite. J. Food Sci., 38, 1067-1069.
Fan T.Y., Tannenbaum S.R. 1973. Factors influencing the rate of formation of nitrosomorpholine from morpholine and nitrite. 2. Rate enhancement in frozen solution. J. Agric. Food Chem., 21, 967-969.
Issenberg P., Tannenbaum S.R. 1973. Approaches to determination of volatile and non-volatile N-nitroso compounds in foods and beverages. IN: N-nitroso compounds and formation of nitrosamines, IARC Scientific Publication No. 3, pp. 31-37.
Mirvish S.S., Sams J., Fan T.Y., Tannenbaum S.R. 1973. Kinetics of nitrosation of the amino acids proline, hydroxyproline, and sarcosine. J. Natl. Canc. Inst., 51, 1833-1839.
Tannenbaum S.R., Fan T.Y. 1973. Uncertainties about nitrosamine formation - in and from foods. Proceedings of the Meat Industry Research Conference, American Meat Institute: Chicago, IL.
1972
Fan T.Y., Tannenbaum S.R. 1972. Stability of N-nitroso compounds. Journal of Food Science, 37, 274-276.
Tannenbaum S.R. 1972. Nitrite and nitrosamine content of foods: unresolved problems and current research. Proc. of the 25th Reciprocal Meat Conference, American Meat Association, Ames, Iowa, National Livestock and Meat Board: Chicago, IL.
1971
Archer M.C., Clark S.D., Thilly J.E., Tannenbaum S.R. 1971. Environmental nitroso compounds: reaction of nitrite with creatine and creatinine. Science, 174, 1341-1343.
Fan T.Y., Tannenbaum S.R. 1971. Automatic colorimetric determination of N-nitroso compounds. Journal of Agricultural and Food Chemistry, 19, 1267-1269.