Please submit abstracts to the ISOM program office.

Authors are asked to observe the following criteria:

The title of the abstract should be concise and in bold. Full capitalization is not necessary.

The name of the Main Author should be underlined, and the name of the individual who will attend the meeting to present the work should be marked with an asterisk (*). Authors should include their address, fax number and e-mail address.

Abstracts should be typed in English using single line, 12 point spacing.

The preferred font is Times New Roman, 12 point.

Chemical structures may be drawn using ChemDraw, ChemWindow or ISIS/Draw.

References, denoted by superscript numbers in the text, should be listed at the end of the text using the Journal of American Chemical Society's format.

Lastname, First Initial. J. Am. Chem. Soc. Year of publication, Issue Number, First page of article - last page of article.

The whole of the abstract must be contained within a rectangle of 230 mm x 165 mm (9.0 x 6.5 inches) in portrait layout.

A camera ready original and an electronic copy in MS Word or similar word processing program is required. Please send electronic files to ISOMXIV@mit.edu.

Below is an example of how a typical abstract should appear:

Molybdenum Alkylidene Catalysts for Asymmetric Olefin Metathesis Reactions

Richard R. Schrock*, # John Alexander, Sherry Zhu Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139 Fax number: (xxx) xxx-xxxx, Email: emailaddress

A variety of enantiomerically pure alkylidene complexes of the type Mo(CHR)(NR')(diolate), where the diolate is a sterically protected biphenolate or binaphtholate, and NR' is a substituted arylimido ligand, have been synthesized and explored as catalysts for asymmetric metathesis reactions.1 These species have been found to efficiently catalyze ring-closing metathesis via desymmetrization to yield five-membered and six-membered rings, tandem asymmetric ring-opening metathesis/cross metathesis, and tandem ring-opening metathesis/ring-closing metathesis to yield products with a %ee in the range of 95 to >99%, rapidly, in some cases in the absence of solvent, and with low catalyst loadings (1%). Recent advances include the synthesis of products that contain asymmetric quaternary carbon centers, the discovery of dramatic temperature and solvent effects, and the synthesis of the first seven-membered ring enantioselectively.

1 (a) Alexander, J. B.; La, D. S.; Cefalo, D. R.; Hoveyda, A.; Schrock, R. R. J. Am. Chem. Soc. 1998, 120, 4041. (b) La, D. S.; Alexander, J. B.; Cefalo, D. R.; Graf, D. D.; Hoveyda, A. H.; Schrock, R. R. J. Am. Chem. Soc. 1998, (italics)120(italics), 9720. (c) Zhu, S. S.; Cefalo, D. R.; La, D. S.; Jamieson, J. Y.; Davis, W. M.; Hoveyda, A. H.; Schrock, R. R. J. Am. Chem. Soc. 1999, 121, 8251. (d) La, D. S.; Ford, J. G.; Sattely, E. S.; Bonitatebus, P. J.; Schrock, R. R.; Hoveyda, A. H. J. Am. Chem. Soc. 1999, 121, 11603. (e) Weatherhead, G. S.; Ford, J. G.; Alexanian, E. J.; Schrock, R. R.; Hoveyda, A. H. J. Am. Chem. Soc. 2000, 122, 1828.