Sharp Lab
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Paul

Paul Boutz
Position:
Fellow
Research: Paul is interested in understanding the mechanisms by which double-stranded RNA molecules enter into mammalian cells. He is also collaborating with Mohini Jangi to continue work done by Cathie Garnis in conjuction with the Broad Institute to identify factors involved in CD44 alternative splicing using an RNAi-based screen.
Education: PhD, UCLA

Meena

Meena Chakraborty
Position:
Undergraduate, UROP
Research: Meena is characterizing the active microRNAs in different embryonic stem cell states. Working with Salil, she is addressing how changes in microRNA activity can drive transitions between different ESC states. Outside of lab, she enjoys choral singing, recreational dance, and walking along the Charles.
Education: Lexington High School, Lexington, MA

Vikash

Vikash P. Chauhan
Position:
Fellow
Research: Vikash is interested in the mechanisms underlying genome editing with RNA-guided nucleases. In particular, he seeks to understand the regulation of DNA repair pathway choice following nuclease activity. He is also developing approaches for enhancing the efficiency of genome editing in vivo.
Education: PhD, Harvard University

Anthony

Anthony Chiu
Position:
Graduate Student
Research: Anthony is interested in understanding noncoding transcription events in our genome. In particular, he is interested in exploring both the mechanisms and functions of divergent transcripts. In addition, he is interested in exploring the phenomenon of enhancer RNAs.
Education: BSc, University of Toronto

Paige

Paige Coles
Position:
Research Associate
Research: Paige is working on developing a system for efficient microRNA capture at the single cell level and is optimizing conditions that allow specific isolation of the Argonaute bound pool of active microRNAs.
Education: MS, Boston University

Sara

Sara Dubbury
Position:
Graduate Student
Research:
Education:

Salil Garg
Position:
Fellow
Research: Salil is investigating the roles small RNAs play in conferring robustness to embryonic stem cell differentiation. Salil and Meena are also working on characterizing the transitions in microRNA activity between different cell states. Salil is also working with Paige Coles and members of Dan Anderson's laboratory on developing a system to analyze microRNAs at the single cell level.
Education: MD, PhD, Harvard-M.I.T. Combined MD-PhD Program

Courtney

Courtney JnBaptiste
Position:
Fellow
Research:
Courtney is interested in understanding regulatory networks involving miRNAs and how they function to enforce specific cell states, particularly the somatic state. He is also interested in exploring the potential tumorigenicity of various miRNA families.
Education: PhD, Massachusetts Institute of Technology

Amanda Maffa
Position:
Lab Manager
Education: BSc, Simmons College

Hiroshi Suzuki

Hiroshi Suzuki
Position: Fellow
Research: Hiroshi is studying the mechanisms of small RNA asymmetry and its relationship with cancer. He is also interested in understanding various noncoding RNAs and exploring development of novel molecular targeted therapy.
Education: MD, PhD, The University of Tokyo

Kevin Thai

Kevin Thai
Position:
Graduate Student
Research: Kevin is investigating the role of Argonaute-2 (Ago2) in tumor progression using mouse models. He is interested in studying the mechanisms that facilitates enhanced cellular transformation when Ago2 is over-expressed in cancer cells and how this may affect gene expression.
Education: BS (bioengineering)- UC San Diego

Amanda Ward
Position:
Fellow
Research: Amanda is interested in understanding mechanistic functions of long non-coding RNAs. In particular, she is determining how long non-coding RNAs help establish imprinted gene expression.
Education: PhD, Baylor College of Medicine
Yue Yue Zhang
Position:
Undergraduate, UROP
Research:Yue is working with Amanda Ward to investigate the mechanisms behind imprinted genes, such as Ube3a, and to elucidate how long non-coding RNAs are involved in establishing such imprinting. Yue is a rising sophomore, and his passions include chemistry, distance running, and learning new things.
Education: DuPont Manual High School, Louisville, KY
 
 

 

 

 

 

 

 

 

 

 

 

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