Voigt Lab  
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We are developing a basis by which cells can be programmed like robots to perform complex, coordinated tasks for pharmaceutical and industrial applications. We are engineering new sensors that give bacteria the senses of touch, sight, and smell. Genetic circuits — analogous to their electronic counterparts — are built to integrate the signals from the various sensors. Finally, the output of the gene circuits is used to control cellular processes. We are also developing theoretical tools from statistical mechanics and non-linear dynamics to understand how to combine genetic devices and predict their collective behavior.

Check out our terminators at Addgene!

Programming language for cells

1. A Programming Language for Cells

Engineering cellular sensors

2. Engineering Cellular Sensors

Organelle refactoring and engineering

3. Organelle Refactoring and Engineering

We are engineering multi-gene prokaryotic systems for applications in biotechnology. Currently, we are focusing on the type III secretion system, which pumps proteins from the cytoplasm, through both membranes, to the extracellular environment. This system is being exploited to deliver heterologous proteins to the growth media. We are also interested in engineering photosynthetic systems to convert sunlight into energetic and specialty chemicals. .

Genome-scale design

4. Genome-Scale Design

Engineering unusual organisms

5. Engineering Unusual Organisms with Unique Capabilities

Sythetic Biology Center at MIT MIT Department of Bioengineering MIT
Synthetic Biology Center @ MIT Department of Biological Engineering Massachusetts Institute of Technology