Maheshri Research Group

Dynamics and variability in gene regulation and function

PI

Narendra Maheshri

narendra at mit dot edu

BS Chemical Engineering, Biology, MIT

PhD Chemical Engineering, Univ. of California, Berkeley

Post-doctoral scholars

Richard I. Joh

rich_joh at mit dot edu

BS

PhD Physics, Georgia Tech

  • Epigenetic switching at FLO11

Tek-Hyung Lee

tekhlee at mit dot edu

BS Chemical Engineering

Seoul National University

PhD Chemical Engineering, MIT

  • Interactions of DNA binding proteins with arrays of binding sites

Graduate Students

Christopher J. (CJ) Zopf

cjzopf at mit dot edu

BS Chemical & Biological Engineering

Columbia

  • Influence of promoter/chromatin architecture on dynamics of gene activation and repression
  • Transcriptional fluctuations

Bradley Neisner

neisner at mit dot edu

BS Chemical Engineering

Rice

  • Recombinase-based strategies for randomizing gene expression state of multiple genes

Shawn Finney-Manchester

spmanche at mit dot edu

BS Chemical Engineering

Brown

  • Methods for in vivo targeted mutagenesis
  • Mutagenic fate of double-strand break/end repair

Katie Quinn

kjquinn at mit dot edu

BS Chemical & Biological Engineering, Molecular Cell Biology

Univ. of Queensland

  • Origin and consequences of transcriptional fluctuations
  • Stochastic models of transcription

Nick Wren

nswren at mit dot edu

BS Chemical & Biological Engineering

Carnegie Mellon

  • Dynamics/delays in gene activation
  • Delay integration into gene circuits

Undergraduate Students

Katherine Zhu

kzhu25 at mit dot edu

Chemical & Biological Engineering

MIT

  • Age-dependence of spontaneous mutation rate

Lab alumni