Probabilistic Computing with p-bits: Optimization, Machine Learning and Quantum Simulation

9th October 2025

Timing : 1 pm ET

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For a list of all talks at the NanoBio seminar Series Fall'25, see here


Positioned at the intersection of classical and quantum computing, probabilistic computing provides a physics-inspired approach to domain-specific computation by harnessing the inherent randomness of devices such as stochastic magnetic tunnel junctions (sMTJs) [1-5]. These devices naturally generate tunable randomness and replace thousands of transistors per p-bit, reducing energy consumption. In this talk, we demonstrate how networks of probabilistic bits (p-bits) in both digital CMOS and hybrid CMOS + sMTJ implementations can accelerate tasks in optimization, machine learning, and statistical inference through asynchronous updates and sparse connectivity. We also describe a distributed FPGA-based prototype that achieves near-linear speedup with minimal overhead, enabling the study of large-scale problems. In particular, we will highlight recent results on 3D Spin Glass systems benchmarked against quantum annealers, showing how targeted architectures can drastically reduce time and energy to solution. The unique combination of intrinsic randomness in sMTJs and flexible CMOS circuits may pave the way for next-generation probabilistic computers that can address computationally intensive, previously intractable tasks in a wide range of applications.