Organic Electronics for Diagnostics in Physiological Media

16th November 2022

Timing : 1 pm EST

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For a list of all talks at the NanoBio seminar Series Fall'22, see here

Organic mixed (ionic and electronic) charge conductors and devices offer a new toolbox for interfacing with biological systems. One application for which they have compelling advantages is medical diagnostics. In this talk, I will show how we make use of the mixed conductivity of these materials and the transistor type that relies on this type of transport to detect pathogens and proteins with performance that exceeds the state-of-the-art. I will introduce two distinct organic electrochemical transistors (OECT) based sensor configurations; one for Amyloid beta aggregates and another that detects coronavirus spike proteins at the physical limit. Having challenged these sensors with patient samples, I will discuss areas where proof-of-concept platforms may fail and how to enhance the device operation in biological environments.