Fall 2004
|
|
Practical Information |
|
|
Lecture Notes and Discussion Papers
Anatomy Discussion Papers
Review: Forge, A. and T. Wright (2002). "The molecular architecture
of the inner ear." Br Med Bull 63: 5-24..
Liberman, M. C. (1980)."Morphological differences among radial afferent
fibers in the cat cochlea: An electron-microscopic study of serial
sections," Hear Res 3, 45-63.
Liberman, M. C. (1982)."Single-neuron labeling in the cat auditory nerve," Science 216, 1239-1241.
Kikuchi, T., Kimura, R. S., Paul, D. L. and Adams, J. C. (1995)."Gap
junctions in the rat cochlea: immunhistochemical and ultrastructural
analysis," Anat Embryol 191, 101-118.
Hair Cells Discussion Papers
Review: Roberts, W. M., J. Howard, et al. (1988). "Hair cells: transduction,
tuning, and transmission in the inner ear." Annu Rev Cell Biol 4:
63-92.
Corey, D. P. and Hudspeth, A. J. (1983)."Kinetics of the receptor current in bullfrog saccular hair cells," J Neurosci 3, 962-976.
Pickles, J.O. , Comis, S.D. and Osborne, M.P. (1984) Cross-links between
stereocilia in the guinea pig organ of Corti, and their possible relation
to sensory transduction. Hear Res 15: 103-112.
Denk W, Holt JR, Shepherd GM, and Corey DP. Calcium imaging of single
stereocilia in hair cells: localization of transduction channels at both
ends of tip links. Neuron 15: 1311-1321, 1995.
Review: Wangemann, P. (2002)."K+ cycling and its regulation in the cochlea and vestibular labyrintl," Audiology Neurootology 7:199-205.
Salt, A. N., Melichar, I. and Thalmann, R. (1987)."Mechanisms of endocochlear
potential generation by stria vascularis," Laryngoscope 97,
984-991.
Takeuchi, S., Ando, M. and Kakigi, A. (2000)."Mechanism generating endocochlear
potential: role played by intermediate cells in stria vascularis,"
Biophys J 79, 2572-2582.
OHCs and Electromotility
Review: Santos-Sacchi, J. (2003) New tunes from Corti's organ: the
outer hair cell boogie rules. Curr. Opin. Neurobio. 13:459-468.
Holley, M. C. and Ashmore, J. F. (1988)."On the mechanism of a high-frequency
force generator in outer hair cells isolated from the guinea pig
cochlea," Proc R Soc Lond B Biol Sci 232, 413-429.
Hallworth, R., Evans, B. N. and Dallos, P. (1993)."The location and
mechanism of electromotility in guinea pig outer hair cells," J. Neurophysiol.
70, 549-558.
Zheng, J., Shen, W., He, D. Z., Long, K. B., Madison, L. D. and Dallos,
P. (2000)."Prestin is the motor protein of cochlear outer hair cells,"
Nature 405, 149-155.
Frequency Tuning and Cochlear Mechanics
Review: Dallos, P. (1992). The active cochlea. J. Neurosci. 12:4575-4585.
Wilson, J. P. and Johnstone, J. R. (1975)."Basilar membrane and middle-ear
vibration in guinea pig measured by capacitive probe," J Acoust
Soc Am 57, 705-723.
Ruggero, M.A. and Rich, N.C. (1991) "Furosemide alters organ of Corti
mechanics: Evidence for feedback of outer hair cells upon the basilar
membrane". J. Neurosci. 11:1057-1067.
Neely, S.T. (1993) A model of cochlear mechanics with outer hair cell motility. J Acoust Soc Amer 94(1) 137-146.
Afferent Transmission Discussion
Papers
Review: Fuchs, P.A., Glowatski, E. and Moser, T. (2003) The afferent synapse of cochlear hair cells. Curr. Opin. Neurobio. 13:452-458.
Roberts, W. M., Jacobs, R. A. and Hudspeth, A. J. (1990)."Colocalization
of ion channels involved in frequency selectivity and synaptic
transmission at presynaptic active zones of hair
cells," J. Neuroscience 10, 3664-3684.
Moser, T. and Beutner, D. (2000)."Kinetics of exocytosis and endocytosis
at the cochlear inner hair cell afferent synapse of the mouse," Proc. Nat.
Acad. Sci. 97, 883-888.
Glowatzki, E. and Fuchs, P. A. (2002)."Transmitter release at the hair cell ribbon synapse," Nat Neurosci 5, 147-154.
Auditory Nerve Response Discussion Papers
Review: Kiang NYS (1984) Peripheral processing of auditory information. Handbook of Physiology – The Nervous System.
Liberman, M. C. (1978)."Auditory-nerve response from cats raised in a low-noise chamber," J Acoust Soc Am 63, 442-455.
Sachs, M. B. and Young, E. D. (1979)."Encoding of steady-state vowels
in the auditory nerve: representation in terms of discharge rate," J.
Acoust. Soc. Am. 66, 470-479.
Young ED and Sachs MB (1980) Representation of steady state
vowels in the temporal aspects of the discharge patterns of populations
of
auditory nerve fibers. J. Acoust. Soc. Amer. 66:1381-1403.
Efferent Control Discussion Papers
Review: Guinan, JJ (1996) Physiology of Cochlear Efferents. In “The Cochlea”, eds. P Dallos, AN Popper and RR Fay. New York, Springer, pp 435-500.
Elgoyhen, A.B., Johnson, D.S., Boulter, J., Vetter, D.E. and Heinemann,
S. (1994) "?9: An acetylcholine receptor with novel pharmacological
properties expressed in rat cochlear hair cells."
Cell: 79-705-715.
Russell, I. J. and Murugasu, E. (1997)."Medial efferent inhibition suppresses
basilar membrane responses to near characteristic frequency tones of
moderate to high intensities," J Acoust Soc Am 102,
1734-1738.
Maison, S. F. and Liberman, M. C. (2000)."Predicting vulnerability to
acoustic injury with a non-invasive assay of olivocochlear reflex strength,"
J.
Neuroscience 20, 4701-4707.
Review: Bryant, J., R. J. Goodyear, et al. (2002). "Sensory
organ development in the inner ear: molecular and cellular mechanisms."
Br Med Bull 63: 39-57.
Manny Groves, A. K. and Bronner-Fraser, M. (2000)."Competence, specification
and commitment in otic placode induction," Development 127, 3489-3499.
Nancy Eddison, M., Le Roux, I. and Lewis, J. (2000)."Notch signaling
in the development of the inner ear: lessons from Drosophila," Proc Natl
Acad Sci U S A 97, 11692-11699.
Trauma and Repair Discussion Papers
Review Trauma: Huang, T., A. G. Cheng, et al. (2000). "Oxidative
stress-induced apoptosis of cochlear sensory cells: otoprotective strategies."
Int J Dev Neurosci 18(2-3): 259-70.
Review Repair: Bermingham-McDonogh, O. and E. W. Rubel (2003). "Hair
cell regeneration: winging our way towards a sound future." Curr
Opin Neurobiol 13(1): 119-26.
Wang, Y., Hirose, K. and Liberman, M. C. (2002)."Dynamics of noise-induced
cellular injury and repair in the mouse cochlea," J Assoc Res
Otolaryngol 3, 248-268.
Pirvola, U., Xing-Qun, L., Virkkala, J., Saarma, M., Murakata, C., Camoratto,
A. M., Walton, K. M. and Ylikoski, J. (2000)."Rescue of hearing,
auditory hair cells, and neurons by CEP-1347/KT7515,
an inhibitor of c-Jun N-terminal kinase activation," J Neurosci 20, 43-50.
Warchol, M. E. and Corwin, J. T. (1996)."Regenerative proliferation
in organ cultures of the avian cochlea: identification of the initial progenitors
and determination of the latency of the proliferative
response," J Neurosci 16, 5466-5477.
Sensorineural Hearing Loss Discussion Papers
Review: To be Announced
Heinz, M.G. and Young, E.D. (2004). "Response Growth With Sound Level
in Auditory-Nerve Fibers After Noise-Induced Hearing
Loss",
J. Neurophysiology 91:784-795.
Liberman, M.C. and Dodds, L.W. (1984) Single-neuron labeling and chronic cochlear pathology, III: Stereocilia damage