Angus. J. Koller; Owen Glaser; Molly C. DeLuca; Rachel N. Motz; Edith K. Amason; Imma Carbo-Bague; Jason C. Mixdorf; Ilia A. Guzei; Eduardo Aluicio-Sarduy; Dariusz Smilowicz; Todd. E. Barnhart; Caterina F. Ramogida; Elizabeth M. Nolan; Jonathan W. Engle; Eszter Boros, ""Off-Label Use" of the Siderophore Enterobactin Enables Targeted Imaging of Cancer with Radioactive Ti(IV)", Angew. Chem. Int. Ed. 2024, online ahead of print.

Chuchu Guo, Elizabeth M. Nolan, "Exploring the Antibacterial activity and Cellular Fates of Enterobactin–Drug Conjugates that Target Gram-negative Bacterial Pathogens", Acc. Chem. Res. 2024, 57, 1046-1056.

Rachel N. Motz, Chuchu Guo, Artur Sargun, Gregory Walker, Martina Sassone-Corsi, Manuela Raffatellu, Elizabeth M. Nolan, "Conjugation to Native and Nonnative Triscatecholate Siderophores Enhances Delivery and Antibacterial Activity of a β-lactam to Gram-negative Bacterial Pathogens", J. Am. Chem. Soc. 2024, 146, 7708-7722.

Chuchu Guo, Kwo-Kwang A. Wang, Elizabeth M. Nolan, "Investigation of Siderophore–platinum(IV) Conjugates Reveals Differing Antibacterial activity and DNA damage Depending on the Platinum Cargo", ACS Infect. Dis. 2024, online ahead of print.




Janet J. Y. Peet, Angelica D. Phan, Amanda G. Oglesby, Elizabeth M. Nolan, "Iron Sequestration by Murine Calprotectin Induces Starvation Responses in Pseudomonas aeruginosa", ACS Infect. Dis. 2024, 10(2), 688-700.

Michelle M. Killian, Megan B. Brophy, Elizabeth M. Nolan, Thomas C. Brunold, "Spectroscopic and Computational Investigations of Cobalt(II) Binding to the Innate Immune Protein Human Calprotectin", J. Biol. Inorg. Chem.  2023, online ahead of print.

Elizabeth M. Nolan, Janet J. Y. Peet, "Post-translational Modifications on the Metal-sequestering Protein Calprotectin", BioMetals  2023, 36, 817.




Romana R. Gerner, Suzana Hossain, Artur Sargun, Kareem Siada, Grant J. Norton, Tengfei Zheng, Wilma Neumann, Sean-Paul Nuccio, Elizabeth M. Nolan, Manuela Raffatellu, "Siderophore Immunization Restricted Colonization of Adherent-Invasive Escherichia coli and Ameliorated Experimental Colitis", mBio 2022, 13, e02184-22.

Chuchu Guo and Elizabeth M. Nolan, "Heavy-Metal Trojan Horse: Enterobactin-Directed Delivery of Platinum(IV) Prodrugs to Escherichia coli", J. Am. Chem. Soc. 2022, 144, 12756.

Tomer Rosen and Elizabeth M. Nolan, "S100A12 Promotes Mn(II) binding to Pneumococcal PsaA and Staphylococcal MntC by Zn(II) Sequestration", J. Inorg. Biochem. 2022, 233, 111862.

Tomer Rosen, Kwo-Kwang A. Wang, Elizabeth M. Nolan, "Metal Sequestration by S100 Proteins in Chemically Diverse Environments," Trends in Microbiology 2022, 30, 654.

Tomer Rosen, Rose C. Hadley, Aaron T. Bozzi, Daniel Ocampo, Jason M. Shearer, Elizabeth M. Nolan, "Zinc Sequestration by Human Calprotectin Facilitates Manganese Binding to the Bacterial Solute-Binding Proteins PsaA and MntC," Metallomics  2022, 14, mfac001.




Adunoluwa Obisesan, Emily M. Zygiel, Elizabeth M. Nolan, "Bacterial Responses to Iron Withholding by Calprotectin," Biochemistry  2021, 60, 3337-3346.

Robert Silvers, Jules R. Stephan, Robert G. Griffin, Elizabeth M. Nolan, "Molecular Basis of Ca(II)-induced Tetramerization and Transition-metal Sequestration in Human Calprotectin," J. Am. Chem. Soc.  2021, 143, 18073-18090.

Cassandra E. Nelson, Weilang Huang, Emily M. Zygiel, Elizabeth M. Nolan*, Maureen A. Kane*, Amanda G. Oglesby*, "The Human Innate Immune Protein Calprotectin Elicits a Multimetal Starvation Response in Pseudomonas aeruginosa," Microbiol. Spectr.  2021, 9, e00519-21. (* denotes co-corresponding author).

Artur Sargun, Martina Sassone-Corsi, Tengfei Zheng, Manuela Raffatellu, Elizabeth M. Nolan, "Conjugation to Enterobactin and Salmochelin S4 Enhances the Antimicrobial Activity and Selectivity of β-Lactam Antibiotics against Nontyphoidal Salmonella," ACS Infect. Dis.  2021, 7, 1238-1259.

Artur Sargun, Timothy C. Johnstone, Hui Zhi, Manuela Raffatellu, Elizabeth M. Nolan, "Enterobactin- and Salmochelin-β-lactam Conjugates Induce Cell Morphologies Consistent with Inhibition of Penicillin-binding Proteins in Uropathogenic Escherichia coli CFT073," Chem. Sci.  2021, 12, 4041-4056.

Artur Sargun, Romana R. Gerner, Manuela Raffatellu*, Elizabeth M. Nolan*, "Harnessing Iron Acquisition Machinery to Target Enterobacteriaceae," Infect. Dis. 2021, 223 (Supplement_3), S307-S313 (* denotes co-corresponding author).

Emily M. Zygiel, Adunoluwa O. Obisesan, Cassandra E. Nelson, Amanda G. Oglesby, Elizabeth M. Nolan, "Heme protects Pseudomonas aeruginosa and Staphylococcus aureus from Calprotectin-induced Iron Starvation," J. Biol. Chem.  2021, 296, 100160.




Yifan Zhang, Katherine A. Edmonds, Daniel J. Raines, Brennan A. Murphy, Hongwei Wu, Chuchu Guo, Elizabeth M. Nolan, Michael S. VanNieuwenhze, Anne-K Duhme-Klair, David P. Giedroc, "The Pneumococcal Iron Uptake Protein (PiuA) Specifically Recognizes Tetradentate Fe(III) bis- and mono-Catecholcomplexes." J. Mol. Biol.  2020, 432, 5390-5410.

Jagat Adhikari, Jules R. Stephan, Don L. Rempel, Elizabeth M. Nolan*, and Michael L. Gross*, "Calcium Binding to the Innate Immune Protein Human Calprotectin Revealed by Integrated Mass Spectrometry," J. Am. Chem. Soc.  2020, 142, 13372–13383 (* denotes co-corresponding author).

Tomer Rosen and Elizabeth M. Nolan, "Metal Sequestration and Antimicrobial Activity of Human Calprotectin are pH-Dependent," Biochemistry  2020, 59, 2468-2478.

Aaron T. Bozzi and Elizabeth M. Nolan, "Avian MRP126 Restricts Microbial Growth through Ca(II)-dependent Zn(II) Sequestration," Biochemistry  2020, 59, 802-817.




Emily M. Zygiel and Elizabeth M. Nolan, "Exploring Iron Withholding by the Innate Immune Protein Human Calprotectin," Acc. Chem. Res.  2019, 52, 2301-2308.

Derek M. Gagnon, Rose C. Hadley, Andrew Ozarowski, Elizabeth M. Nolan*, and R. David Britt*, "High-Field EPR Spectroscopic Characterization of Mn(II) Bound to the Bacterial Solute-Binding Proteins MntC and PsaA," J. Phys. Chem. B   2019, 123, 4929-4934 (* denotes co-corresponding author).

Rose C. Hadley, Derek M. Gagnon, Andrew Ozarowski, R. David Britt, and Elizabeth M. Nolan, "Murine Calprotectin Coordinates Mn(II) at a Hexahistidine Site with Ca(II)-dependent Affinity," Inorg. Chem.  2019, 58, 13578-13590 (invited contribution to a special Forum Article issue on metals in biology).

Emily M. Zygiel, Cassandra E. Nelson, Luke K. Brewer, Amanda G. Oglesby-Sherrouse*, and Elizabeth M. Nolan*, "The Human Innate Immune Protein Calprotectin Induces Iron Starvation Responses in Pseudomonas aeruginosa," J. Biol. Chem.  2019, 294, 3549-3562 (* denotes co-corresponding author).

Rose C. Hadley and Elizabeth M. Nolan, "Preparation and Iron Redox Speciation Study of the Fe(I)-binding Antimicrobial Protein Calprotectin," Meth. Mol. Biol.  2019, 1929, 397-415 (invited contribution to a protocol book entitled "Calcium-binding Proteins: From Structural Basis and Functional Diversity to Medical Application")

Lisa S. Cunden and Elizabeth M. Nolan, "Preparation of the Oxidized and Reduced Forms of Psoriasin (S100A7)," Meth. Mol. Biol.  2019, 1929, 379-395 (invited contribution to a protocol book entitled "Calcium-binding Proteins: From Structural Basis and Functional Diversity to Medical Application")



Jules R. Stephan, Fangting Yu, Rebekah M. Costello, Benjamin S. Bleier, and Elizabeth M. Nolan. "Oxidative Post-translational Modifications Accelerate Proteolytic Degradation of Calprotectin," J. Am. Chem. Soc.  2018, 140, 17444-17455.

Christopher E. R. Richardson, Elizabeth M. Nolan, Matthew D. Shoulders, and Stephen J. Lippard, "A Sensitive, Non-radioactive Assay for Zn(I) Uptake into Metazoan Cells," Biochemistry  2018, 57, 6807-6815.

Hyuck Jin Lee, Masha G. Savelief, Juhye Kang, Megan Brunjes Brophy, Toshiki G. Nakashige, Shin Jung C. Lee, Elizabeth M. Nolan, and Mi Hee Lim, "Calprotectin influences the aggregation of metal-free and metal-bound amyloid-beta by direct interaction," Metallomics  2018, 10, 1116-1127.

Wilma Neumann and Elizabeth M. Nolan, "Evaluation of a Reducible Disulfide Linker for Siderophore-mediated Delivery of Antibiotics," J. Biol. Inorg. Chem.  2018, 23, 1025-1036 (invited contribution to a special issue honoring Professor Alison Butler, 2018 Alfred Bader Award recipient).

Toshiki G. Nakashige, Sarah E. J. Bowman, Emily M. Zygile, Catherine L. Drennan*, and Elizabeth M. Nolan*, "Biophysical Examination of the Calcium-modulated Nickel-binding Properties of Human Calprotectin Reveals Conformational Change in the EF-hand Domains and His3Asp site," Biochemistry  2018, 57, 4155-4164 (* denotes co-corresponding author).

Cristina Y. Zamora, Amael G. E. Madec, Wilma Neumann, Elizabeth M. Nolan, and Barbara Imperiali, "Design, Solid-phase Synthesis and Evaluation of Enterobactin Analogs for Iron Delivery into the Human Pathogen Campylobacter jejuni," Bioorg. Med. Chem.  2018, 26, 5314-5321 (invited contribution to a special issue honoring Professor Laura Kiessling, 2017, Tetrahedron Prize recipient).

Rose C. Hadley, Yu Gu, and Elizabeth M. Nolan, "Initial Biochemical and Functional Evaluation of Murine Calprotectin Reveals Ca(II)-Dependence and Its Ability to Chelate Multiple Nutrient Transition Metal lons," Biochemistry  2018, 57,2846-2856.

Emily M. Zygiel and Elizabeth M. Nolan. "Transition Metal Sequestration by the Host-Defense Protein Calprotectin," Ann. Rev. Biochem.  2018, 87, 621-643.

Wilma Neumann, Martina Sassone-Corsi, Manuela Raffatellu, and Elizabeth M. Nolan. "Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity," J. Am. Chem. Soc.  2018, 140, 5193-5201.

Lisa S. Cunden and Elizabeth M. Nolan. "Bioinorganic Explorations of Zn(II) Sequestration by Human S100 Host-Defense Proteins," Biochemistry  2018, 57, 1673-1680.

Christopher E. R. Richardson, Lisa S. Cunden, Vincent L. Butty, Elizabeth M. Nolan, Matthew D. Shoulders, and Stephen J. Lippard. "A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency," J. Am. Chem. Soc.  2018, 140, 2413-2416.

Rose C. Hadley, Derek M. Gagnon, Megan Brunjes Brophy, Yu Gu, R. David Britt, and Elizabeth M. Nolan. "Biochemical and Spectroscopic Observation of Mn(II) Sequestration from Bacterial Mn(II) Transport Machinery by Calprotectin," J. Am. Chem. Soc.  2018, 140, 110-113.


Elizabeth M. Nolan. "A Non-canonical Role for Yersiniabactin in Bacterial Copper Acquisition," Biochemistry  2017, 56, 6073-6074 (Viewpoint).

Lisa S. Cunden, Megan Brunjes Brophy, Grayson E. Rodriguez, Hope A. Flaxman, and Elizabeth M. Nolan. "Biochemical and Functional Evaluation of the Intramolecular Disufide Bonds in the Zinc-Chelating Antimicrobial Protein Human S100A7 (Psoriasin)," Biochemistry  2017, 56, 5726-5738.

Timothy C. Johnstone and Elizabeth M. Nolan. "Determination of the Molecular Structure of Ferric Enterobactin and Ferric Enantioenterobactin using Racemic Crystallography" J. Am. Chem. Soc.  2017, 139, 15245-15250.

Toshiki G. Nakashige, Emily M. Zygiel, Catherine L. Drennan, and Elizabeth M. Nolan. "Nickel Sequestration by the Host- Defense Protein Human Calprotectin," J. Am. Chem. Soc.  2017, 139, 8828-8836.

Toshiki G. Nakashige and Elizabeth M. Nolan. "Human Calprotectin Affects the Redox Speciation of Iron," Metallomics  2017, 9, 1086-1095.

Wilma Neumann, Rose C. Hadley, and Elizabeth M. Nolan. "Transition Metals at the Host-pathogen Interface: How Neisseria Exploit Human Metalloproteins for Acquiring Iron and Zinc," Essays Biochem.  2017, 61, 211-223.

Phoom Chairatana and Elizabeth M. Nolan. "Human alpha-Defensin 6: a Small Peptide that Self-Assembles and Protects the Host by Entangling Pathogens," Acc. Chem. Res.  2017, 50, 960-967.

Wilma Neumann, Anmol Gulati, and Elizabeth M. Nolan. "Metal Homeostasis in Infectious Disease: Recent Advances in Bacterial Metallophores and the Human Metal-Withholding Response," Curr. Opin. Chem. Biol.  2017, 37, 10-18.

Phoom Chairatana, I-Ling Chiang. and Elizabeth M. Nolan. "Human alpha-Defensin 6 Self-Assembly Prevents Adhesion and Suppresses Virulence Traits of Candida albicans," Biochemistry  2017, 56, 1033-1041.

Phoom Chairatana and Elizabeth M. Nolan. "Defensins, Lectins, Mucins and Secretory Immunoglobulin A: Microbe-Binding Biomolecules that Contribute to Mucosal Immunity in the Human Gut," Crit. Rev. Biochem. Mol. Biol.  2017, 52, 45-56.

Tessa M. Baker, Toshiki G. Nakashige, Elizabeth M. Nolan*, and Michael L. Neidig*. "Magnetic Circular Dichroism Studies of Iron(II) Binding to Human Calprotectin," Chem. Sci.  2017, 8, 1369-1377 (* denotes co-corresponding author).


Martina Sassone-Corsi^, Phoom Chairatana^, Tengfei Zheng, Araceli Perez-Lopez, Robert A. Edwards, Michael D. George, Elizabeth M. Nolan*, and Manuela Raffatellu*. "Siderophore-based Immunization Strategy to Inhibit Growth of Enteric Pathogens." Proc. Natl. Acad. Sci. U. S. A.  2016, 113, 13462-13467 (^ denotes co-first author, * denotes co-corresponding author).

Mohammed Shabab, Markus F. F. Arnold, Jon Penterman, Andrew J. Wommack, Hartmut T. Bocker, Paul A. Price, Joel S. Griffitts, Elizabeth M. Nolan*, and Graham C. Walker*. "Disulfide Cross-linking Influences Symbiotic Activities of Nodule Peptide NCR247," Proc. Natl. Acad. Sci. U. S. A.  2016, 113, 10157-10162 (* denotes co-corresponding author).

Toshiki G. Nakashige, Jules R. Stephan, Lisa S. Cunden, Megan Brunjes Brophy, Brenna C. Keegan, Jason M. Shearer, and Elizabeth M. Nolan. "The Hexahistidine Motif of Host-Defense Protein Human Calprotectin Contributes to Zinc Withholding and Its Functional Versatility," J. Am. Chem. Soc.  2016, 138, 12243-12251.

Elizabeth M. Nolan. "BIOCHEMISTRY: A Metal Shuttle Keeps Pathogens Well Fed," Science  2016, 352, 1055-1056 (invited perspective).

Lisandro J. Gonzalez, Guillemo Bahr, Toshiki G. Nakashige, Elizabeth M. Nolan, Robert A. Bonomo, and Alejandro J. Vila. "Membrane Anchoring Stabilizes and Favors Secretion of New Delhi Metallo-beta-lactamase," Nat. Chem. Biol.  2016, 12, 516-522.

Phoom Chairatana, Hiutung Chu, Patricia A. Castillo, Bo Shen, Charles L. Bevins, and Elizabeth M. Nolan. "Proteolysis Triggers Self-Assembly and Unmasks Innate Immune Function of a Human alpha-Defensin Peptide," Chem. Sci.  2016, 7, 1738-1752.

Jules R. Stephan and Elizabeth M. Nolan. "Calcium-induced Tetramerization and Zinc Chelation Shield Human Calprotectin from Degradation by Host and Bacterial Extracellular Proteases," Chem. Sci.  2016, 7, 1962-1975.

Lisa S. Cunden, Aleth Gaillard, and Elizabeth M. Nolan. "Calcium Ions Tune the Zinc-Sequestering Properties and Antimicrobial Activity of Human S100A12," Chem. Sci.  2016, 7, 1338-1348.

Toshiki G. Nakashige, Bo Zhang, Carsten Krebs, and Elizabeth M. Nolan. Human Calprotectin Is an Iron-Sequestering Host-Defense Protein," Nat. Chem. Biol.  2015, 11, 765-771.

Julie L. H. Madsen, Timothy C. Johnstone, and Elizabeth M. Nolan. "Chemical Synthesis of Staphyloferrin B Affords Insight into the Molecular Structure, Iron Chelation, and Biological Activity of a Polycarboxylate Siderophore Deployed by the Human Pathogen Staphylococcus aureus," J. Am. Chem. Soc.  2015, 137, 9117-9127.

Phoom Chairatana, Tengfei Zheng, and Elizabeth M. Nolan, Targeting Virulence: Salmochelin Modification Tunes the Antibacterial Activity Spectrum of Beta-Lactams for Pathogen-Selective Killing of Escherichia coli," Chem. Sci.  2015, 6, 4458-4471.

Tengfei Zheng and Elizabeth M. Nolan, "Evaluation of (Acyloxy)alkyl Ester Linkers for Antibiotic Release from Siderophore-Antibiotic Conjugates," Bioorg. Med. Chem. Lett.  2015, 25, 4987-4991 (invited contribution for the 25th anniversary edition).

Timothy C. Johnstone and Elizabeth M. Nolan, "Beyond Iron: Non-Classical Functions of Bacterial Siderophores," Dalton Trans.  2015, 44, 6320-6339.

Megan Brunjes Brophy and Elizabeth M. Nolan, "Manganese and Microbial Pathogenesis: Sequestration by the Mammalian Immune System and Utilization by Microorganisms," ACS Chem. Biol.  2015, 10, 641-651.

Haritha R. Chileveru, Shion A. Lim, Phoom Chairatana, Andrew J. Wommack, I-Ling Chiang, and Elizabeth M. Nolan, "Visualizing Attack of Escherichia coli by the Antimicrobial Peptide Human Defensin 5," Biochemistry  2015, 54, 1767-1777.

Derek M. Gagnon, Megan Brunjes Brophy, Sarah E. J. Bowman, Troy A. Stich, Catherine L. Drennan, R. David Britt, and Elizabeth M. Nolan, "Manganese Binding Properties of Human Calprotectin Under Conditions of High and Low Calcium: X-ray Crystallographic and Advanced Electron Paramagnetic Resonance Spectroscopic Analysis," J. Am. Chem. Soc.  2015, 137, 3004-3016.

Stephanie E. Woods, Monika R. Leonard, Joshua A Hayden, Megan Brunjes Brophy, Kara R. Benert, Brigitte Lavoie, Sureshkumar Muthupalani, Mark T. Wharey, Gary M. Mave, Elizabeth M. Nolan, Martin C. Carey, and James G. Fox, "Impaired Cholecystokinin-Induced Gallbladder Emptying Incriminated in Spontaneous "Black" Pigment Gallstone Formation in Germ-free Swiss Webster Mice," Am. J. Phys. Gastrointest. Liver Pathol.  2015, 308, G335-G349.

Simone Moser, Haritha R. Chileveru, Jill Tomaras, and Elizabeth M. Nolan, "A Bacterial Mutant Library as a Tool to Study the Attack of a Defensin Peptide," ChemBioChem  2014, 15, 2684-2688.

Andrew J. Wommack, Joshua J. Ziarek, Jill Tomaras, Haritha R. Chileveru, Yunfei Zhang, Gerhard Wagner, and Elizabeth M. Nolan, "Discovery and Characterization of a Disulfide-Locked C2-Symmetric Defensin Peptide," J. Am. Chem. Soc.  2014, 136, 13494-13497.

Tengfei Zheng and Elizabeth M. Nolan, "Enterobactin-Mediated Delivery of Beta-Lactam Antibiotics Enhances Antibacterial Activity Against Pathogenic Escherichia coli," J. Am. Chem. Soc.  2014, 136, 9677-9691.

Megan Brunjes Brophy, Toshiki G. Nakashige, Aleth Gaillard, and Elizabeth M. Nolan, "Contributions of the S100A9 C-Terminal Tail to High-Affinity Mn(II) Chelation by the Host-Defense Protein Human Calprotectin," J. Am. Chem. Soc.  2013, 135, 17804-17817.

Yunfei Zhang, Fabien B. L. Cougnon, Yoshitha A. Wanniarachchi, Joshua A. Hayden, and Elizabeth M. Nolan, "Reduction of Human Defensin 5 Affords a High-Affinity Zinc-Chelating Peptide," ACS Chem. Biol.  2013, 8, 1907-1911.

Joshua A. Hayden, Megan Brunjes Brophy, Lisa. S. Cunden, and Elizabeth M. Nolan, "High-Affinity Manganese Coordination by Human Calprotectin Is Calcium-Dependent and Requires the Histidine-Rich Site at the Dimer Interface," J. Am. Chem. Soc.  2013, 135, 775-787.

Andrew J. Wommack, Scott A. Robson, Yoshitha A. Wanniarachchi, Andrea Wan, Christopher J. Turner, Gerhard Wagner and Elizabeth M. Nolan, "NMR Solution Structure and Condition-Dependent Oligomerization of the Antimicrobial Peptide Human Defensin 5," Biochemistry  2012, 51, 9624-9637.

Tengfei Zheng, Justin L. Bullock, and Elizabeth M. Nolan, "Siderophore-Mediated Cargo Delivery to the Cytoplasm of Escherichia coli and Pseudomonas aeruginosa. Syntheses of Monofunctionalized Enterobactin Platforms and Evaluation of Enterobactin-Cargo Conjugate Uptake," J. Am. Chem. Soc.  2012, 134, 18388-18400.

Megan Brunjes Brophy, Joshua A. Hayden, and Elizabeth M. Nolan, "Calcium Ion Gradients Modulate the Zinc Affinity and Antibacterial Activity of Human Calprotectin," J. Am. Chem. Soc.  2012, 134, 18089-18100.

Tengfei Zheng and Elizabeth M. Nolan, "Siderophore-Based Detection of Fe(II) and Microbial Pathogens" (review), Metallomics 2012, 24, 866-880 (invited contribution to the Emerging Investigators issue).

Yoshitha A. Wanniarachchi, Piotr Kaczmarek, Andrea Wan and Elizabeth M. Nolan, "Human Defensin 5 Disulfide Array Mutants: Disulfide Bond Deletion Attenuates Antibacterial Activity against Staphylococcus aureus," Biochemistry  2011, 50, 8005-8017.


Matthias Strieker, Elizabeth M. Nolan, Christopher T. Walsh and Mohamed A. Marahiel, "Stereospecific Synthesis of threo- and erythro-B-Hydroxyglutamic Acid During Kutzneride Biosynthesis," J. Am. Chem. Soc.  2009, 131, 13523-13530.

Christopher T. Walsh and Elizabeth M. Nolan, "Chemical Biology and Natural Product Discovery" (commentary), ChemBioChem  2009, 10, 24-25.

Elizabeth M. Nolan and Christopher T. Walsh, "How Nature Morphs Peptide Scaffolds into Antibiotics" (review), ChemBioChem  2009, 10, 34-53.

Elizabeth M. Nolan and Christopher T. Walsh, "Investigations of the MceIJ-Catalyzed Posttranslational Modification of the Microcin E492 C-Teminus: Linkage of Ribosomal and Nonribosomal Peptides to Form 'Trojan Horse' Antibiotics," Biochemistry  2008, 47, 9289-9299.

Christopher T. Walsh and Elizabeth M. Nolan, "Morphing Peptide Backbones into Heterocycles" (commentary), Proc. Natl. Acad. Sci. U. S. A.   2008, 105, 5655-5656.

Rebecca F. Roush, Elizabeth M. Nolan, Frank Löhr and Christopher T. Walsh, "Maturation of an Escherichia coli Ribosomal Peptide by ATP-Consuming N--P Bond Formation," J. Am. Chem. Soc.  2008, 130, 3603-3609.

Elizabeth M. Nolan, Michael A. Fischbach, Alexander Koglin and Christopher T. Walsh, "Biosynthetic Tailoring of Microcin E492m Post-Translational Modification Affords an Antibacterial Siderophore-Peptide Conjugate," J Am. Chem. Soc.  2007, 129, 14336-14347.

Michael L Neidig, Christina D. Brown, Ken Light, Danica Galonić Fujimori, Elizabeth M. Nolan, John C. Price, Eric W. Barr, J. Martin Bollinger, Jr., Carsten Krebs, Christopher T. Walsh and Edward I. Solomon, "CD and MCD of CytC3 and Taurine Dioxygenase: Role of the Facial Triad in α-KG-Dependent Oxygenases, J. Am. Chem. Soc.  2007, 129, 14224-14231.


Elizabeth M. Nolan and Stephen J. Lippard, "Small-Molecule Fluorescent Sensors for Exploring Zinc Metallo-neurochemistry," Acc. Chem. Res.  2009, 42, 193-203.

Elisa Tomat, Elizabeth M. Nolan, Jacek Jaworski and Stephen J. Lippard, "Organelle-Specific Zinc Detection Using Zinpyr Labeled Fusion Proteins in Live Cells," J. Am. Chem. Soc.  2008, 130, 15776-15777

Elizabeth M. Nolan and Stephen J. Lippard, "Tools and Tactics for the Optical Detection of Mercuric Ion," Chem. Rev.  2008, 108, 3443-3480.

Elizabeth M. Nolan and Stephen J. Lippard, "Turn-On and Ratiometric Detection of Mercury in Water with a Red-Emitting Probe," J. Am. Chem. Soc.  2007, 129, 5910-5918.

Elizabeth M. Nolan, Jubin W. Ryu, Jacek Jaworski, Rodney P. Feazell, Morgan Sheng and Stephen J. Lippard, "Zinspy Sensors with Enhanced Dynamic Range for Imaging Neuronal Cell Zinc Uptake and Mobilization," J. Am. Chem. Soc.  2006, 128, 15517-15528.

Elizabeth M. Nolan, Jacek Jaworski, Maryann E. Racine, Morgan Sheng and Stephen J. Lippard, "Moderate Affinity Fluorescent Zinc Sensors of the Zinpyr Family: Syntheses, Characterization and Biological Imaging Applications," Inorg. Chem.  2006, 45, 9748-9757.

Elizabeth M. Nolan, Maryann E. Racine and Stephen J. Lippard, "Selective Hg(II) Detection in Aqueous Solution with Thiol Derivatized Fluoresceins," Inorg. Chem.  2006, 45, 2742-2749.

Elizabeth M. Nolan, Jacek Jaworski, Ken-lchi Okamoto, Yasunori Hayashi, Morgan Sheng, and Stephen J. Lippard, "QZ1 and QZ2 Rapid, Reversible Quinoline-Derivatized Fluoresceins for Sensing Biological Zn(II)," J. Am. Chem. Soc.  2005, 127, 16812-16823.

Elizabeth M. Nolan and Stephen J. Lippard, "MS4, a Seminaphthofluorescein-based Chemosensor for the Ratiometric Detection of Hg(II)," J. Mater. Chem. 2005, 27-28, 2778-2783 (highlighted in Chemistry World, July 2005).

Christopher J. Chang, Elizabeth M. Nolan, Jacek Jaworski, Ken-Ichi Okamoto, Yasunori Hayashi, Morgan Sheng and Stephen J. Lippard, "ZP8, a Neuronal Zinc Sensor with Improved Dynamic Range, Imagining Zinc in Hippocampal Slices with Two-Photon Microscopy," Inorg. Chem.  2004, 43, 6774-6779.

Elizabeth M. Nolan and Stephen J. Lippard, "The Zinspy Family of Fluorescent Zinc Sensors: Syntheses and Spectroscopic Investigations," Inorg. Chem.  2004, 43, 8310-8317.

Elizabeth M. Nolan, Shawn C. Burdette, Jessica J. Harvey, Scott A. Hilderbrand and Stephen J. Lippard, "Synthesis and Characterization of Zinc Sensors Based on a Monosubstituted Fluorescein Platform," Inorg. Chem.  2004, 43, 2624-2635.

Christopher J. Chang, Elizabeth M. Nolan, Jacek Jaworski, Shawn C. Burdette, Morgan Sheng, and Stephen J. Lippard, "Bright Fluorescent Chemosensor Platforms for Imaging Endogenous Pools of Neuronal Zinc," Chem. Biol.  2004, 11, 203-210.

Christopher J. Chang, Jacek Jaworski, Elizabeth M. Nolan, Morgan Sheng, and Stephen J. Lippard, "A Tautomeric Chemosensor for the Ratiometric Fluorescence Imaging of NO-Induced Release of Intracellular Zinc," Proc. Natl. Acad. Sci. U. S. A.  2004, 101, 1129-1134.

Elizabeth M. Nolan and Stephen J. Lippard, "A Turn-On' Fluorescent Sensor for the Selective Detection of Mercuric Ion in Aqueous Media, J. Am. Chem. Soc.  2003, 125, 14270-14271 (in Thompson ESI Special Topics, June 2005).


Elizabeth M. Nolan and R. G. Linck, "Through Space Charge and Dipolar Effects in Substituted Ethanes and 1,1,1- Trifuoroethanes," J. Phys. Chem. A.  2002, 106, 533-543.

Elizabeth M. Nolan and R. G. Linck, "An Exploration of Long Range Substituent Effects in Substituted Alkanes," J. Phys. Chem. A.  2001, 105, 7297-7307.

Elizabeth M. Nolan and R. G. Linck "Charges in Substituted Alkanes: Evidence for a Through Space Mechanism," J. Am. Chem. Soc.  2000, 122, 11497-11506.


Elizabeth M. Nolan, "Let's Visualize Biology Chemistry and Cellular Imaging," Letters to a Young Chemist, Abhik Gosh, Ed., Wiley, Chapter 8, 2011.