19th Enzyme Mechanisms Conference |
January 5th-9th, 2005 |
Conference Speakers |
New Ways to Look at Intermediates
Discussion Leader: Chris Walsh |
|
Speakers |
Poster Talks |
Neil Kelleher |
Sean Elliot |
| University of Illinois | Boston University |
| Kinetic and Regiospecific Interrogation of Polyketide and Lantibiotic Intermediates using Large Molecule FT Mass spectrometry | Probing Enzyme Mechanisms with Protein Film Voltammetry |
Brian Hoffman |
Zeyne Oekten |
| Northwestern University | Stanford University |
| Characterizing the Invisible: EPR and ENDOR Studies of Enzymatic Intermediates, Nitrogenase | Myosin VI Walks Hand over Hand |
Stephen J. Benkovic |
|
| Pennsylvania State University | |
| A Kinetic Sampler | |
Macromolecular Machines
Discussion Leader: Irene Lee |
|
Speakers |
Poster Talks |
Peter Walter |
Stuart Licht |
| University of California at San Francisco | Massachusetts Institute of Technology |
| Mechanism of SRP-Dependent Protein Targeting | How a Processive Protease Measures Product Size Mapping Active Sites in Complex Proteomes |
Robert T. Sauer |
|
| Massachusetts Institute of Technology | |
| ATP-Dependent Proteases at Work | |
New Chemical Transformations
Discussion Leader: Cathy Drennan |
|
Speakers |
Poster Talks |
Squire Booker |
J. M. Bollinger |
| Pennsylvania State University | Pennsylvania State University |
| Lipoic Acid Biosynthesis: Understanding Sulfur Insertion into Unactivate Alkyl Chains | Dissection of the Mechanism of the Fe(II) a Ketoglutarate Dioxygenase: TauD |
Rolf Thauer |
Ruma Banerjee |
| Max-Planck Institute of Microbiology | University of Nebraska |
| Methyl-coenzyme M reductase and the anaerobic oxidation of methane | Radical Enzymes and their Escorts |
Wolfgang Buckel |
|
| Philipps-Universitat | |
| Characterization of an enzyme bound ketyl radical anion | |
New Approaches to Design of Therapeutics
Discussion Leader: Brian Hubbard |
|
Speakers |
|
K. Barry Sharpless |
|
| The Scripps Research Institute | |
| "In Situ: Click Chemistry: Enzyme Inhibitors Made to Their Own Specifications | |
J. Wells |
|
| Sunesis | |
| Drug Discovery at Adaptive Surfaces | |
Benjamin F. Cravatt |
|
| The Scripps Research Institute | |
| Mapping Active Sites in Complex Proteomes | |
Genomics and Structure: Understanding Specificity
Discussion Leader: Tadhg Begley |
|
Speakers |
Poster Talks |
John Blanchard |
Brian Miller |
| Albert Einstein School of Medicine | University of Wisconsin-Madison |
| Structure and Function of Bacterial N-Acetyltransferaces | Identifying Latent Enzyme Activities: Substrate Ambiguity within Modern Bacterial Sugar Kinases |
Tadgh Begley |
Vahe Bandarian |
| Cornell University | University of Arizona |
| Tryptophan Catabolism: Gene Identification and Mechanistic Studies | |
Reinhard Sterner |
|
| University of Regensburg | |
| Evolution and design of (ba) 8-barrel enzymes | |
Computational Methods
Discussion Leader: Tom Bruice |
|
Speakers |
|
Rama Ranganathan |
|
| University of Texas Southwestern | |
| Determining Structural Motifs for Allosteric Communication in Proteins | |
Sharon Hammes-Schiffer |
|
| Pennsylvania State University | |
| Impact of Enzyme Motion on Activity | |
F. Neese |
|
| Max-Planck Institute of Bioinorganic Chemistry | |
| Identifying Intermediates in Enzymatic Reaction Cycles through Quantum Chemical Calculation of their Spectroscopic Properties: Recent Progress and Perspectives | |
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