Fibronectins in vivo

1. Pulina, M.V., Hou, S.Y., Mittal, A., Julich, A., Whittaker, C.A., Holley, S.A., Hynes, R.O. and Astrof, S. (2011). Essential roles of fibronectin in the development of the left-right embryonic body plan. Dev. Biol. 354(2):208-220. Apr 2. (Epub ahead of print). PMCID: PMC3225965
2. Astrof, S. and Hynes, R.O. (2009). Fibronectins in Vascular Morphogenesis. Angiogenesis. 12(2):165-75. Epub 2009 Feb 14. PMCID: PMC2716138
3. Shinde, A.V., Bystroff, C., Wang, C., Vincent, P.A., Vogelezang, M.G., Hynes, R.O. and Van De Water, L. (2008). EIIIA (ED-A), the alternatively spliced segment of fibronectin, exhibits cryptic cell adhesive activity to integrin α9β1. J. Biol. Chem. 283: 2858-2870. doi: 10.1074/jbc.M708306200
4. Astrof, S., Kirby, A., Lindblad-Toh, K, Daly, M. and Hynes, R.O. (2007). Heart development in fibronectin-null mice is governed by a genetic modifier on chromosome four. Mech. Devel. 124:551-8. PMID: 17628448
5. Astrof, S., Crowley, D. and Hynes, R.O. (2007).  Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Devel. Biol. 311: 11-24. PMCID: PMC2080666
6. Matuskova, J., Chauhan, A.K., Cambien, B., Astrof, S., Dole, V.S., Piffath, C.L., Hynes, R.O. and Wagner, D.D. (2006).  Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles. Arteriosclerosis, Thrombosis and Vasc. Biol. 26: 1391-1396.
7. Singh, P., Reimer, C., Peters, J.H., Stepp, M.A., Hynes, R.O. and Van De Water, L. (2004). The spatial and temporal expression pattern of integrin α9β1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing. J.Invest. Dermatol. 123:1176-1181.
   
8. Astrof, S., Crowley, D., George, E.L., Fukuda, T., Sekiguchi, K., Hanahan, D. and Hynes, R.O. (2004). Direct test of potential roles of EIIIA and EIIIB alternatively spliced variants of fibronectin in physiological and tumor angiogenesis. Mol. Cell Bio. 19: 8662-8670.
   
9. Peters, J.H., Loredo, G.A., Chen, G., Maunder, R., Hahn, T.J.,Willits, W. and Hynes.R.O. (2003). Plasma levels of fibronectin bearing the alternatively spliced EIIIB segment are increased in patients following major trauma. J.Lab. Clin. Med. 141: 401-410.
   
10. George, E.L., Baldwin, H.S. and Hynes, R.O. (1997). Fibronectins are essential for heart and blood vessel morphogenesis, but are dispensible for initial specification of precursor cells. Blood 90: 3073-3086.
    
11. Georges-Labouesse, E.N., George, E.L., Rayburn, H. and Hynes, R.O. (1996) Mesodermal development in murine embryos mutated in the fibronectin gene Developmental Dynamics 207:145-156
    
12. Peters, J. H., Chen, G., and Hynes, R.O. (1996) Fibronectin isoform distribution in the mouse II. Differential distribution of the alternatively spliced EIIIB, EIIIA and V segments in the adult mouse. Cell Adhesion and Comm., 4: 126-148.
    
13. Peters, J. H., and Hynes, R.O. (1996) Fibronectin isoform distribution in the mouse I. The alternatively spliced EIIIB, EIIIA and V segments show widespread codistribution in the developing mouse embryo. Cell Adhesion and Comm., 4: 103-125.
    
14. Peters, J., Trevithick, J.E., Johnson, P. and Hynes, R.O. (1995). Expression of the alternatively spliced EIIIB segment of fibronectin. Cell Adhes. and Commun. 3:67-89.
    
15. Nickeleit, V., Zagachin, L., Nishikawa, K., Peters, J.H., Hynes, R.O. and Colvin, R.B. (1995). Embryonic fibronectin isoforms are synthesized in crescents in experimental autoimmune glomerulonephritis in the rat.). Amer. J. Path. 147:965-978.
    
16. George, E.L., Georges-Labouesse, E.N., Patel-King, R.S., Rayburn, H. and Hynes, R.O. (1993) Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 119:1079-1091.
    
17. ffrench-Constant, C., Hynes, R.O., Heasman, J., Wylie, C.C. (1992). Fibronectins and embryonic cell migration. In: Formation and Differentiation of Early Embryonic Mesoderm. ed. Bellairs, R. et al. Plenum Press, New York. pp. 99-108.
    
18. Smith, J.C., Symes, K., Hynes, R.O. and DeSimone, D. (1990). Mesoderm induction and the control of gastrulation in Xenopus laevis: the roles of fibronectin and integrins. Development 108:229-238.
    
19. ffrench-Constant, C., Van De Water, L., Dvorak, H.F. and Hynes, R.O. (1989). Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat. J. Cell Biol. 109:903-914.
    
20. ffrench-Constant, C. and Hynes, R.O. (1989). Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. Development 106:375-388.
    
21. ffrench-Constant, C. and Hynes R.O. (l988). Patterns of fibronectin gene expression and splicing during cell migration in chicken embryos. Development 104:369-382.
    
22. Hynes, R.O., Patel, R. and Miller, R.H. (1986). Migration of neuroblasts along preexisting axonal tracts during prenatal cerebellar development. J. Neuroscience 6:867-876.
    
23. Lee, G., Hynes, R.O. and Kirschner, M. (1984). Temporal and spatial regulation of fibronectin in early Xenopus development. Cell 36:729-740.
    Heasman, J., Hynes, R.O., Swan, A.P., Thomas, V. and Wylie, C.C. (1981). Primordial germ cells of Xenopus embryos: the role of fibronectin in their adhesion during migration. Cell 27:437-447.
    
24. Mayer B.W., Jr., Hay, E.D. and Hynes, R.O. (1981). Immunocytochemical localization of fibronectin in embryonic chick trunk and area vasculosa. Dev. Biol. 82:267-286
    
25. Courtoy, P.J., Kanwar, Y.S., Hynes, R.O. and Farquhar, M.G. (1980). Fibronectin localization in the rat glomerulus. J. Cell Biol. 87:691-696.
    
26. Critchley, D.R., England, M.A., Wakely, J. and Hynes, R.O. (1979). Distribution of fibronectin in the ectoderm of gastrulating chick embryos. Nature 280:498-500.
    
27. Schachner, M., Shoonmaker, G. and Hynes, R.O. (1978). Cellular and subcellular localization of LETS protein in the nervous system. Brain Res. 158:149-158.