1. Sobolev, O., Stern, P., Lacy-Hulbert, A., Hynes, R. O. (2009). Natural killer cells use selectins for suppression of subcutaneous tumors. Cancer Res. 69:2531-2539. (Epub ahead of print, Mar 3). PMCID: PMC2694740
  2. Izawa, A., Ueno, T., Jurewicz, M., Ito, T., Tanaka, K., Takahashi, M., Ikeda, U., Sobolev, O., Fiorina, P., Smith, R.N., Hynes, R.O. and Abdi, R. (2007). Importance of donor- and recipient-derived selectins in cardiac allograft rejection. J. Am. Soc. Nephrol. 18:2929-2936. doi: 10.1681/ASN.2006111261
  3. Taverna, D., Moher, H., Crowley, D., Borsig.L., Varki, A. and Hynes, R.O. (2004). Increased primary tumor growth in mice null for β3- or β3/β5-integrins or selectins. Proc. Natl. Acad. Sci. USA 101: 763-768.
  4. Borsig, L., Wong, R., Hynes, R.O., Varki, N.M. and Varki, A. (2002). Synergistic effect of L- and P-selectin in facilitating tumor metastasis in a syngeneic system involving non-mucin ligands - further evidence for selectin inhibition as a mode of heparin action. Proc. Natl. Acad. Sci. USA 99: 2193-2198.
  5. Niederman, R., Westernoff, T., Lee, C., Mark, L.L., Kawashima, N., Ullman-Culleré, M., Dewhirst, F.E., Paster, B.J., Wagner, D.D., Mayadas, T., Hynes, R.O. and Stashenko, P. (2001). Infection-mediated early onset periodontal disease in P-/E-selectin knockout mice. J.Clin. Periodontol. 28:569-575.
  6. Robinson, S.D., Frenette, P.S., Rayburn, H., Cummiskey, M., Ullman-Cullere, M., Wagner, D.D. and Hynes, R.O. (1999). Multiple targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. Proc. Natl. Acad. Sci. USA 96: 11452-11457.
  7. Kawashima, N., Neiderman, R., Ullman-Culleré, M., Hynes, R.O. and Stashenko, P. (1999). Infection-stimulated infraosseus inflammation and bone destruction is increased in P-/E-selectin knockout mice. Immunol. 97: 117-123.
  8. Robert, C., Fuhlbrigge, R.C., Kieffer, J.D., Ayehunie, S., Ruprecht, R., Hynes, R.O., Cheng, G., Wong, T.H., Grabbe, S., von Andrian, U.H. and Kupper, T.S. (1999) Interaction of dendritic cells with skin endothelium: new perspective on immunosurveillance. J. Exp. Med.. 189: 627-635.
  9. Hartwell, D.W., Butterfield, C.E., Frenette, P.S., Kenyon, B.M., Hynes, R.O., Folkman, J. and Wagner, D.D. (1998). Angiogenesis in P-selectin- and E-selectin-deficient mice. Microcirculation, 5: 173-178.
  10. Hartwell, D.W., Mayadas, T.N., Frenette, P.S., Berger, G., Rayburn, H., Hynes, R.O. and Wagner, D.D. (1998) Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory processes. J. Cell Biol. 143: 1129-1141.
  11. Homeister, J.W., Zhang, M., Frenette, P.S., Hynes, R.O., Wagner, D.D., Lowe, J.B. and Marks, R.M. (1998). Overlapping functions of E- and P-selectin in neutrophil accumulation during acute dermal inflammation. Blood 92:2345-2352.
  12. DeMora, F., Williams, C.M.M., Frenette, P.S., Wagner, D.D., Hynes, R.O. and Galli, S.J. (1998). P- and E-selectin are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin. Lab. Invest. 78:497-505.
  13. Mazo, I.B., Gutierrez-Ramos, J.C., Frenette, P.S., Hynes, R.O., Wagner, D.D. and von Andrian, U.H. (1998). Stem cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and VCAM-1. J. Exp. Med. 188:465-474.
  14. Seiler, K.P., Ma, Y., Weis, J.H., Frenette, P.S., Hynes, R.O., Wagner, D.D. and Weis, J.J. (1998). E and P selectins are not required for resistance to severe murine lyme arthritis. Infection and Immunity 66:4557-4559.
  15. Dong, Z.M., Chapman, S.M., Brown, A.A., Frenette, P.S., Hynes, R.O. and Wagner, D.D. (1998). The combined role of P- and E-selectins in atherosclerosis. . J. Clin. Invest. 102: 145-152.
  16. Frenette, P.S., Moyna, C., Hartwell, D.W., Lowe, J.B., Hynes, R.O. and Wagner, D.D. (1998). Platelet-endothelial interactions in inflamed mesenteric venules. Blood, 91: 1318-1324.
  17. Subramaniam, M., Saffaripour, S., Van De Water, L., Frenette, P.S., Mayadas, T.N., Hynes, R.O., and Wagner, D.D. (1997). Role of endothelial selectins in wound repair. Am. J. Path. 150: 1701-1709.
  18. Johnson, R.C., Chapman, S.M., Dong, Z.M., Ordovas, J.M., Mayadas, T.N., Herz, J.I., Hynes, R.O., Schaefer, E.J. and Wagner, D.D. (1997). Absence of P-selectin delays fatty streak formation in mice. J. Clin. Invest., 99: 1037-1043
  19. Mayadas, T.N., Mendrick, D.L., Brady, H.R., Tang, T., Papayianni, A., Assmann, K.J.M., Wagner, D.D., Hynes, R.O. and Cotran, R.S. (1996). Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice. Kidney Internatl., 49:1342-1349.
  20. Tang, T., Frenette, P.S., Hynes, R.O., Wagner, D.D. and Mayadas, T.N. (1996). Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. J. Clin. Invest. 97:2485-2490.
  21. Subramaniam, M., Frenette, P.S., Saffaripour, S., Johnson, R.C., Hynes, R.O. and Wagner, D.D. (1996). Defects in hemostasis in P-selectin-deficient mice Blood 87:1238-1242.
  22. Yamada, S., Mayadas, T.N., Yuan, F., Wagner, D.D., Hynes, R.O., Melder, R.J. and Jain, R.K. (1996). Rolling in P-selectin deficient mice is reduced but not eliminated in the dorsal skin. Blood 86: 3487-3492.
  23. Pinsky, D.J., Naka, Y., Liao, H., Oz, M.C. , Wagner, D.D., Mayadas, T., Johnson, R., Hynes, R.O., Heath, M., Lawson, C.A. and Stern, D.M. (1996). Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies: a mechanism for rapid neutrophil recruitment following cardiac preservation. J. Clin. Invest. 97:493-500.
  24. Frenette, P.S., Mayadas, T.N., Rayburn, H., Hynes, R.O. and Wagner, D.D. (1996) Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell 84: 563-574
  25. Frenette, P.S., Johnson, R.C., Hynes, R.O. and Wagner, D.D. (1995). Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc. Natl. Acad. Sci. USA: 92:7450-7454.
  26. Johnson, R.C., Mayadas, T.N., Frenette, P,S., Mebius, R.E., Subramaniam, M., Lacasce, A., Hynes, R.O. and Wagner, D.W. (1995). Blood cell dynamics in P-selectin-deficient mice. Blood 86:1106-1114.
  27. Subramaniam, M., Saffaripour, S., Watson, S.R., Mayadas, T.N., Hynes, R.O. and Wagner, D.D. (1995). Reduced recruitment of inflammatory cells in a contact hypersensitivy response in P-selectin-deficient mice. J. Exp. Med. 181 : 2277-2282
  28. Mayadas, T.N., Johnson R.C., Rayburn, H. , Hynes, R.O. and Wagner, D.D. (1993) Leukocyte rolling and extrαvasation are severely compromised in P-selectin-deficient mice. Cell 74:541-554.