Thrombospondin

  1. Lawler, J., Miao, W.M., Duquette, M., Bouck, N., Bronson, R.T. and Hynes, R.O. (2001). Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice. Am.J. Path. 159: 1949-1956
  2. Rodriguez-Manzaneque, J.C., Lane, T.F., Ortega, M.A., Hynes, R.O., Lawler, J. and Iruela-Arispe, M.L. (2001). Thrombospondin-1 suppresses spontaneous tumor growth and angiogenesis and inhibits activation of matrix metalloprotease-9 and mobilisation of VEGF. Proc. Natl. Acad. Sci. USA 98: 12485-12490.
  3. Crawford, S.E., Stellmach, V., Murphy-Ullrich, J., Ribeiro, S.F., Lawler, J., Hynes, R.O., Boivin, G.P., and Bouck, N. (1998). Thrombospondin is an activator of TGF- b in vivo. Cell 93: 1158-1170.
  4. Lawler, J., Sunday, M., Thibert, V., Duquette, M., George, E.L., Rayburn, H. and Hynes, R.O. (1998). Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. J. Clin. Invest. 101:982-992.
  5. Stellmach, V., Volpert, O.V., Crawford, S.E., Lawler, J., Hynes, R.O. and Bouck, N. (1997) Tumor suppressor genes and angiogenesis: the role of p53 in fibroblasts. Eur. J. Cancer 32A: 2394-2400.
  6. Lawler, J. and Hynes, R.O. (1989). An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin. Blood 74:2022-2027.
    Lawler, J., Weinstein, R. and Hynes, R.O. (1988). Cell attachment to thrombospondin: the role of Arg-Gly-Asp, calcium and integrin receptors. J. Cell Biol. 107:2351-2361.
  7. Lawler, J. and Hynes, R.O. (1987). Structural Organization of the Thrombospondin Molecule. in Seminars in Thrombosis and Hemostasis. 13:245-253. (Thieme Medical Publishers, Inc. New York, NY).
  8. Lawler, J. and Hynes, R.O. (1986). The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins. J. Cell Biol. 103:1635-1648.
  9. Lahαv, J., Schwartz, M.A. and Hynes, R.O. (1982). Analysis of platelet adhesion using a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen. Cell 31:253-262.