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Mouse Lines

Status of Generating Mouse Lines

Completed Vector Designs

The following mouse lines will be generated by the Mouse Transgenics Core (F). The dates of completion of each step are indicated. "Completed" Vector Design entries link to a description of the vector design.

Targeted Gene Colony Code Name1 Gene Symbol2
Name of Enzyme or Protein
Vector Design Construct Vector Isolate primary ES Clones3 Isolate cre-modified ES clones Verification of ES clones Generate Chimeric Mice Select Heterozygous Mice Breed Homozygous Mice
Langerin LA Langerin-pending Langerhans cell specific C-type lectin Completed Dec 2002 C2: Feb 2003
B4: Jul 2004
N/A May 2003 May 2003 in progress  
DcSign DC Cd209a-pending CD209a antigen Completed Mar 2003 C2: Jul 2003
B4: May 2004
N/A C2: Feb 2003 C2: Mar 2004 in progress  
SignR1 SB Cd209b-pending CD209b antigen Completed Jun 2003 C2: Sept 2003
B4: Jun 2004
Jul 2004 Aug 2004 Jul 2004    
Mincle MN Clecsf9 C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9 Completed Mar 2003 C2: Jun 2003
B4: Aug 2004
Aug 2003 in progress      
Galectin9 GJ Lgals9 Lectin, galactose-binding, soluble 9 Completed N/A N/A N/A N/A N/A May 2003 Aug 2003
Dectin2 DT Clecsf10 C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10 Completed May 2004            
SiglecH SH N/A Sialic acid-binding immunoglobulin-like lectin H Completed May 2004 in progress          
Dcir DR Clecsf6 Dendritic Cell Immuno Receptor Completed Jul 2003 C2: Oct 2003
B4: Jun 2004
SignR3 SD CD209d-pending CD209d antigen, Dendritic Cell Specific ICAM Grabbing Nonintegrin Related 3 Completed Oct 2003 B4: Feb 2004 May 2004 Apr 2004 Apr 2004 in progress  
Mcl MC Clecsf8 C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8, Macrophage C-type lectin Completed Nov 2003 B4: Jan 2004 May 2004 Feb 2004 Mar 2004 in progress  
Dcar DA N/A Dendritic cell activating immuoreceptor Completed Apr 2004            
Pomgnt1 PM N/A O-mannosyl b1,2 N-acetylglucosaminyltransferase 1 Completed May 2004            
Galectin4 GE Lgals4 Lectin, galactose-binding, soluble 4 in progress              
Galectin8 GH Lgals8 Lectin, galactose-binding, soluble 8 in progress              

1 CFG internal mouse line identifier, specific and unique for each construct, background and type of mutation

2 As per the Mouse Genomic Nomenclature Committee (MGNC) maintained by Mouse Genome Informatics (MGI) of The Jackson Laboratory

3 ES lines: C2 = CMTII (Specialty Media); B4 = Bruce 4

N/A, not applicable

Expected Mouse Lines

Available Mouse Lines

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Last Updated Wednesday, 01-Sep-2004 18:29:15 EDT . Please contact us with comments/questions.

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