Steven R. Tannenbaum

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Research

Publications

Original articles and reviews: Chemical Toxicology: 2010-

[1960-1979] [1980-1989] [1990-1999] [2000-2009] [2010-]

Contact Ms. Marcia Ross for reprints or preprints: mross@mit.edu.

Skipper PL, Kim MY, Sun HL, Wogan GN, Tannenbaum SR. 2010. Monocyclic aromatic amines as potential human carcinogens: old is new again. Carcinogenesis. 31(1):50-8.

Slade PG, Williams MV, Brahmbhatt V, Dash A, Wishnok JS, Tannenbaum SR. 2010. Proteins Modified by the Lipid Peroxidation Aldehyde 9,12-Dioxo-10(E)-dodecenoic Acid in MCF7 Breast Cancer Cells. Chem Res Toxicol Feb 4 [Epub ahead of print]

Song YA, Chan M, Celio C, Tannenbaum SR, Wishnok JS, Han J. 2010. Free-Flow Zone Electrophoresis of Peptides and Proteins in PDMS Microchip for Narrow pI Range Sample Prefractionation Coupled with Mass Spectrometry. Anal Chem. Feb 17.[Epub ahead of print]

North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. 2010. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proc Natl Acad Sci U S A. 107(40):17315-20.

McBee ME, Zeng Y, Parry N, Nagler CR, Tannenbaum SR, Schauer DB. 2010. Multivariate modeling identifies serum neutrophil- and TH 17-related factors as differential biomakers of chronic murine colitis. PLoS One. 5(10):e13277.

Liberman RG, Skipper PL, Tannenbaum SR. 2010. BEAMS Lab at MIT: Status report. Nucl Instrum Methods Phys Res B. 263(7-8):887-890.

Barglow KT, Knutson CG, Wishnok JS, Tannenbaum SR, Marletta MA. 2011. Site-specific and redox-controlled S-nitrosation of thioredoxin. Proc Natl Acad Sci USA.108(35):E600-6. PMID: 21849622

Slade PG, Williams MV, Chang A, Iffrig E, Tannenbaum SR, Wishnok JS. 2011. A filtered database search algorithm for endogenous serum protein carbonyl modifications in a mouse model of inflammation. Mol Cell Proteomics. 10(10):M111.007658. PMID: 21768395

Ross AB, Vuong LT, Ruckle J, Synal HA, Schulze-König T, Wertz K, Rümbeli R, Liberman RG, Skipper PL, Tannenbaum SR, Bourgeois A, Guy PA, Enslen M, Nielsen IL, Kochhar S, Richelle M, Fay LB, Williamson G. 2011. Lycopene bioavailability and metabolism in humans: an accelerator mass spectrometry study. Am J Clin Nutr. 93(6):1263-73.

Watzek N, Böhm N, Feld J, Scherbl D, Berger F, Merz KH, Lampen A, Reemtsma T, Tannenbaum SR, Skipper PL, Baum M, Richling E, Eisenbrand G. 2012. N7-glycidamide-Guanine DNA adduct formation by orally ingested acrylamide in rats: a dose-response study encompassing human diet-related exposure levels. Chem Res Toxicol. 25(2):381-90. PMID: 22211389

Raczynski AR,Muthupalani S, Schlieper K, Fox JG, Tannenbaum SR, Schauer DB. 2012. Enteric Infection with Citrobacter Rodentium Induces Coagulative Liver Necrosis and Hepatic Inflamma. PLoS One.7(3):e33099. PMC3302869

Daniel R, Mores M, Kitchen R, Sundquist M, Hauser T, Stodola M, Tannenbaum SR, Skipper P, Liberman R, Young G, Corless S, Tucker M. 2012. Development of a Commercial Automated Laser Gas Interface (ALGI) for AMS. Elsevier [In Press]

Mangerich A, Knutson CG, Parry NM, Muthupalani S, Ye W, Prestwich E, Cui L, McFaline JL, Mobley M, Ge Z, Taghizadeh K, Wishnok JS, Wogan GN, Fox JG, Tannenbaum SR, Dedon PC. 2012. Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer. Proc Natl Acad Sci U S A. 109(27):E1820-9. PMID: 22689960/PMCID: 3390855

Ho WE, Cheng C, Peh HY, Xu F, Tannenbaum SR, Ong CN, Wong WS. 2012. Anti-malarial drug artesunate ameliorates oxidative lung damage in experimental allergic asthma.Free Radic Biol Med. 53(3):498-507. PMID: 22634146

Eisenbrand G, Gates KS, Hecht SS, Janzowski C, Keefer LK, Marnett LJ, Tannenbaum SR. 2012. Richard loeppky (1937-2012). Chem Res Toxicol. 25(6):1155-6. PMID: 22632260

Raczynski AR, Muthupalani S, Schlieper K, Fox JG, Tannenbaum SR, Schauer DB. 2012. Enteric infection with Citrobacter rodentium induces coagulative liver necrosis and hepatic inflammation prior to peak infection and colonic disease. PLoS One. 7(3):e33099. PMID: 22427959/PMCID: 3302869

Lu K., Knutson C.G., Wishnok J.S., Fox J.G., Tannenbaum S.R. (2012) Serum metabolomics in a Helicobacter hepaticus mouse model of Inflammatory Bowel Disease reveals important changes in the microbiome, serum peptides, and intermediary metabolism. J Proteome Res., [Epub ahead of print]. PMID:22957933

Wogan, G.N., Dedon, P.C., Tannenbaum, S.R., Fox, J.G. (2012) Infection, inflammation and colon carcinogenesis. Oncotarget, 3(8):737-8. PMID:22964519

Mangerich A, Knutson CG, Parry NM, Muthupalani S, Ye W, Prestwich E, Cui L, McFaline JL, Mobley M, Ge Z, Taghizadeh K, Wishnok JS, Wogan GN, Fox JG, Tannenbaum SR, Dedon PC. 2012. Infectioninduced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer. Proc Natl Acad Sci U S A. 109(27):E1820-9. PMCID: 3390855

Ho WE, Cheng C, Peh HY, Xu F, Tannenbaum SR, Ong CN, Wong WS. 2012. Anti-malarial drug artesunate ameliorates oxidative lung damage in experimental allergic asthma. Free Radic Biol Med. 53(3):498-507. PMID: 22634146

Louissaint NA, Cao YJ, Skipper PL, Liberman RG, Tannenbaum SR, Nimmagadda S, Anderson JR, Everts S, Bakshi RP, Fuchs EJ, Hendrix C. 2013. Single Dose Pharmacokinetics of Oral Tenofovir in Plasma, Peripheral Blood Mononuclear Cells, Colonic and Vaginal Tissue. AIDS Res Hum Retroviruses, 29(11):1443-50. PMC3809387 [available 2014/11/1]

Song YA, Wu L, Tannenbaum SR, Wishnok JS, Han J. 2013. Tunable membranes for free-flow zone electrophoresis in PDMS microchip using guided self-assembly of silica microbeads. Anal Chem. 85(24):11695-9. PMC3896612 [Available on 2014/12/17]

Seneviratne U, Godoy LC, Wishnok JS, Wogan GN, Tannenbaum SR. 2013. Mechanism-Based Triarylphosphine-Ester Probes for Capture of Endogenous RSNOs. J Am Chem Soc. 135(20):7693-704. PMC3663071

Knutson CG, Mangerich A, Zeng Y, Raczynski AR, Liberman RG, Kang P, Ye W, Prestwich EG, Lu K, Wishnok JS, Korzenik JR, Wogan GN, Fox JG, Dedon PC, Tannenbaum SR. 2013. Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease. Proc Natl Acad Sci USA 110(26):E2332-41. PMC3696795

Kumar Y, Liang C, Limmon GV, Liang L, Engelward BP, Ooi EE, Chen J, Tannenbaum SR. 2014. Molecular analysis of serum and bronchoalveolar lavage in a mouse model of influenza reveals markers of disease severity that can be clinically useful in humans. PLoS One 5;9(2):e86912. PMC3914809

Lu K, Cable PH, Abo RP, Ru H, Graffam ME, Schlieper KA, Parry NM, Levine S, Bodnar WM, Wishnok JS, Styblo M, Swenberg JA, Fox JG, Tannenbaum SR. 2013. Gut microbiome perturbations induced by bacterial infection affect arsenic biotransformation. Chem Res Toxicol. 26(12):1893-903. PMC3974266

Lu K, Abo RP, Schlieper KA, Graffam ME, Levine S, Wishnok JS, Swenberg JA, Tannenbaum SR, Fox JG. 2014. Arsenic exposure perturbs the gut microbiome and its metabolic profile in mice: an integrated metagenomics and metabolomics analysis. Environ Health Perspect. 122(3):284-91. PMC3948040

Lu K, Mahbub R, Cable PH, Ru H, Parry NM, Bodnar WM, Wishnok JS, Styblo M, Swenberg JA, Fox JG, Tannenbaum SR. 2014. Gut microbiome phenotypes driven by host genetics affect arsenic metabolism. Chem Res Toxicol. 27(2):172-4. PMC3997221

Ho WE, Xu YJ, Xu F, Cheng C, Peh HY, Huang SM, Tannenbaum, SR, Ong CN, Wong WSF. 2014. Anti-malarial drug artesunate restores metabolic changes in experimental allergic asthma. Metabolomics. DOI 10.1007/s11306-014-0699-x

Chao MW, Erkekoglu PN, Tseng CY, Ye W, Trudel LJ, Skipper PL, Tannenbaum SR, Wogan GN. 2015. Protective effects of ascorbic acid against the genetic and epigenetic alterations induced by 3,5-dimethylaminophenol in AA8 cells. J Appl Toxicol. 35(5):466-77. PMID 25178734

Darby A, Lertpiriyapong K, Sarkar U, Seneviratne U, Park DS, Gamazon ER, Batchelder C, Cheung C, Buckley EM, Taylor NS, Shen Z, Tannenbaum SR, Wishnok JS, Fox JG. 2014. Cytotoxic and pathogenic properties of Klebsiella oxytoca isolated from laboratory animals. PLoS One. 2014 Jul 24;9(7):e100542. PMC4109914

Erkekoglu P, Chao MW, Ye W, Ge J, Trudel LJ, Skipper PL, Kocer-Gumusel B, Engelward BP, Wogan GN, Tannenbaum SR. 2014. Cytoplasmic and nuclear toxicity of 3,5-dimethylaminophenol and potential protection by selenocompounds. Food Chem Toxicol. Oct;72:98-110. PMID 25014158

Chao MW, Erkekoglu P, Tseng CY, Ye W, Trudel LJ, Skipper PL, Tannenbaum SR, Wogan GN. 2014. Intracellular generation of ROS by 3,5-dimethylaminophenol: persistence, cellular response, and impact of molecular toxicity. Toxicol Sci. 2014 Sep;141(1):300-13. PMC4271125

Lee YH, Tan CW, Venkatratnam A, Tan CS, Cui L, Loh SF, Griffith L, Tannenbaum SR, Chan JK. 2014. Dysregulated sphingolipid metabolism in endometriosis. J Clin Endocrinol Metab. 99(10):E1913-21. PMID 24960545

Ho WE, Xu YJ, Cheng C, Peh HY, Tannenbaum SR, Wong WS, Ong CN. 2014. Metabolomics Reveals Inflammatory-Linked Pulmonary Metabolic Alterations in a Murine Model of House Dust Mite-Induced Allergic Asthma. J Proteome Res. MID: 24956233

Sarkar U , Rivera-Burgos D , Large EM , Hughes DJ , Ravindra KC , Dyer RL , Ebrahimkhani MR , Wishnok JS , Griffith LG , Tannenbaum SR . 2015. Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor. Drug Metab Dispos. 43(7):1091-9. PMID: 25926431

Ravindra KC, Ho WE, Cheng C, Godoy LC, Wishnok JS, Ong CN, Wong WS, Wogan GN, Tannenbaum SR. 2015. Untargeted Proteomics and Systems-Based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial Cells. Chem Res Toxicol. 2015 Oct 19;28(10):1903-13. PMID 26340163

Yu J, Cilfone NA, Large EM, Sarkar U, Wishnok JS, Tannenbaum SR, Hughes DJ, Lauffenburger DA, Griffith LG, Stokes CL, Cirit M. 2015. Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration. CPT Pharmacometrics Syst Pharmacol. 2015 Oct;4(10):585-94. PMC 4625863

Rivera-Burgos D, Sarkar U, Lever AR, Avram MJ, Coppeta JR, Wishnok JS, Borenstein JT, Tannenbaum SR. 2015. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. Drug Metab Dispos. PMID 26586376

Ravindra KC, Trudel LJ, Wishnok JS, Wogan GN, Tannenbaum SR, Skipper PL. 2016. Hydroxyphenylation of Histone Lysines: Post-translational Modification by Quinone Imines. ACS Chem Biol. PMID 26866676

Wang J, Zhang J, Zhang CJ, Wong YK, Lim TK, Hua ZC, Liu B, Tannenbaum SR, Shen HM, Lin Q. 2016. In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line. Sci Rep. Feb 26;6:22146. PMC 4768257

Seneviratne U, Nott A, Bhat VB, Ravindra KC, Wishnok JS, Tsai LH, Tannenbaum SR. 2016. S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration. Proc Natl Acad Sci USA. PMC 4839463

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