Publications

Original articles and reviews: Chemical Toxicology: 1990-1999

[1960-1979]   [1980-1989]   [1990-1999]   [2000-2009]   [2010-]

Contact Ms. Marcia Ross for reprints or preprints: mross@mit.edu.

M. Maclure, M.S. Bryant, P.L. Skipper and S.R. Tannenbaum. 1990. Decline of the hemoglobin adduct of 4-aminobyiphenyl in quitting smokers. Cancer Res. 50, 181-184.

P.L. Skipper and S.R. Tannenbaum. 1990. The role of protein adducts in the study of chemical carcinogenesis. Mutation and the Environment, Part C, Wiley-Liss, Inc., New York, pp. 301-310.

P. Vineis, N. Caporaso, S. Tannenbaum, P. Skipper, J. Glogowski, H. Bartsch, M. Coda, G. Talaska and F. Kadlubar. 1990. The acetylation phenotype, carcinogen-hemoglobin adducts, and cigarette smoking. Cancer Res. 50, 3002-3004.

S. Naylor, L-S. Gan, B.W. Day, R. Pastorelli, P.L. Skipper, and S.R. Tannenbaum. 1990. Benzo[a]pyrene diol epoxide adduct formation in the mouse and human-hemoglobin: physico­chemical basis for dosimetry. Chem. Res. Toxicol. 3, 111-117.

C.D. Leaf, J.S. Wishnok, J.P. Hurley, W.D. Rosenblad, J.G. Fox and S.R. Tannenbaum. 1990. Nitrate biosynthesis in rats, ferrets and humans. Precursor studies with L-arginine. Carcinogenesis 11, 855-858.

Y. Sahali, P.L. Skipper and S.R. Tannenbaum. 1990. A new syntheses of cyclopenta [cd] pyrene 3,4-oxide and 4-pyrenyl acetic acid. J. Org. Chem., 55, 2918-2920.

P.L. Skipper and S.R. Tannenbaum. 1990. Protein adducts in the molecular dosimetry of chemical carcinogens. Carcinogenesis 11, 507-518.

G. Ronco, P. Vineis, M.S. Bryant and S.R. Tannenbaum. 1990. Haemoglobin adducts formed by aromatic amines in smokers: sources of inter-individual variability. Brit. J. Cancer, 61, 534-537.

P. Correa, W. Haenszel, C. Cuello, D. Zavala, E. Fontham, G. Zarama, S. Tannenbaum, T. Collazos and B. Ruiz. 1990. Gastric precancerous process in a high risk population: Cross-sec­tional studies. Cancer Res. 50, 4731-4736.

P. Correa, W. Haenszel, C. Cuello, D. Zavala, E. Fontham, G. Zarama, S. Tannenbaum, T. Collazos and B. Ruiz. 1990. Gastric precancerous process in a high risk population: Cohort follow-up. Cancer Res. 50, 4737-4740.

B.W. Day, P.L. Skipper, J.S. Wishnok, J. Coughlin, S.K. Hammond, P. Gann and S.R. Tannenbaum. 1990. Identification of an in vivo chrysene diol epoxide adduct in human hemoglobin. Chem. Res. Toxicology. 3, 340-343.

B.W. Day, S. Naylor, L.-S. Gan, Y. Sahali, T.T. Nguyen, P.L. Skipper, J.S. Wishnok and S.R. Tannenbaum. 1990. Molecular dosimetry of polycyclic aromatic hydrocarbon epoxides and diol epoxides via hemoglobin adducts. Cancer Res., 50, 4611-4618.

R. Jankowiak, B.W. Day, P.-Q. Lu, M.M. Doxtader, P.L. Skipper, S.R. Tannenbaum, and G.J. Small. 1990. Fluorescence line-narrowing spectral analysis of in vitro human hemoglobin-benzo(a)pyrene adducts: comparison to synthetic analogues. J. Amer. Chem. Soc. 112, 5866-5869.

V. Prevost, D.E.G. Shuker, H. Bartsch, R. Pastorelli, W.G. Stillwell, L.J. Trudel, and S.R. Tannenbaum. 1990. The determination of urinary 3-methyladenine by immunoaffinity chro­matography monoclonal antibody-based ELISA: use in human biomonitoring studies. Carcinogenesis 11, 1747-1751.

P.L. Skipper and S.R. Tannenbaum. 1990. Protein adducts as biomarkers for chemical carcino­gens. In: Genetic Toxicology of Complex Mixtures, Environ. Sci. Res., Vol. 39,. M.D. Walters et al. (Ed.) Plenum Publishing, NY, pp. 323-330.

H. Bartsch, N. Caporaso, M. Coda, F.F. Kadlubar, C. Malaveille, P. Skipper, G. Talaska, S.R. Tannenbaum, and P. Vineis. 1990. Carcinogen-hemoglobin adducts, urinary mutagenicity and metabolic phenotype in active and passive cigarette smokers. J. Natl. Canc. Inst. 82, 1826-1831.

M.M. Doxtader, B.W. Day, S.R. Tannenbaum and R.R. Dasari. 1990. Analysis of macromolecu­lar adducts of carcinogens by fluorescence line narowing spectroscopy. In: Laser Spectroscopy and Nonlinear Optics (S. Radhakrisna and B.C. Tan, Eds.), Springer-Verlag, pp. 294-304.

W.G. Stillwell, H-X. Xu, J. Glogowski, J.S. Wishnok, S.R. Tannenbaum and P. Correa. 1991. Comparison of urinary nitrate, N-nitrosoproline, 7-methylguanine, and 3-methyladenine in a human population at risk for gastric cancer. In: Relevance to Human Cancer of N-nitroso Compounds, Tobacco Smoke and Mycotoxins. (I.K. O’Neill, J. Chen and H. Bartsch (eds.), IARC Scientific Publication No. 105, International Agency for Research on Cancer: Lyon, France, pp. 83-87.

W.G. Stillwell, J. Glogowski, H.-X. Xu, J.S. Wishnok, D. Zavala, G. Montes, P. Correa, and S.R. Tannenbaum. 1991. Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine and 7-methylguanine in a Colombian population at high risk for stomach cancer. Cancer Res. 51, 190-194.

S.R. Tannenbaum, J.S. Wishnok and C.D. Leaf. 1991. Inhibition of nitrosamine formation by ascorbic acid. American Journal of Clinical Nutrition Supplement 53, S247-S250.

J. Coghlin, P.H. Gann, S.K. Hammond, P.L. Skipper, K. Taghizadeh, M. Paul, and S.R. Tannenbaum. 1991. 4-Aminobiphenyl hemoglobin adducts in fetuses exposed to the tobacco smoke carcinogen in utero. J. Natl. Can. Inst., 83, 274-280.

B.W. Day, S. Naylor, L-S. Gan, Y. Sahali, T.T. Nguyen, P.L. Skipper, J.S. Wishnok, and S.R. Tannenbaum. 1991. Gas Chromatographic/mass spectrometric analysis of diols and tetrols from reactions of polycyclic aromatic hydrocarbon epoxides with hemoglobin. J. Chromatogr., 562, 563-571.

C.D. Leaf, J.S. Wishnok, and S.R. Tannenbaum. 1991. Endogenous incorporation of nitric oxide from L-arginine into N-nitrosomorpholine stimulated by Escherichia coli lipoploysaccha­ride in the rat. Carcinogenesis 12, 537-539.

S.R. Tannenbaum. 1991. Hemoglobin-carcinogen adducts as molecular biomarkers in epi­demiology. IN: Xenobiotics and Cancer. Implications for Chemical Carcinogenesis and Cancer Chemotherapy. L. Ernster et al. eds., Tokyo, Japan Scientific Societies Press; London, Taylor & Francis Ltd. pp 351-360.

B.W. Day, P.L. Skipper, R.H. Rich, S. Naylor, and S.R. Tannenbaum. 1991. Conversion of a hemoglobin alpha-chain aspartate(47) ester N-(2,3-dihydroxypropyl)-asparagine as a method for the identification of the principal binding site for benzo[a]pyrene anti-diol epoxide. Chem. Res. Toxicol. 4, 359-363.

F.F. Kadlubar, K.L. Dooley, C.H. Teitel, D.W. Roberts, R.W. Benson, M.A. Butler, J.R. Bailey, J.F. Young, P.L. Skipper, and S.R. Tannenbaum. 1991. Frequency of urination and its effects on metabolism, pharmacokinetics, blood hemoglobin adduct formation, and liver and urinary bladder DNA adduct levels in beagle dogs given the carcinogen, 4-aminobiphenyl. Cancer Res. 51, 4371-4377.

B.W. Day, P.L. Skipper, J. Zaia, and S.R. Tannenbaum. 1991. Benzo[a]pyrene anti-diol epoxide covalently modifies human serum albumin carboxylate side chains and imidazole side chain of histidine(146). J. Amer. Chem. Soc. 113, 8505-8509.

S.R. Tannenbaum. 1991. Bladder cancer in workers exposed to aniline. J. Natl. Canc. Inst. 83, 1507-1508.

A. Weston, N.E. Caporaso, R.N. Hoover, S.R. Tannenbaum, P.L. Skipper, J.H. Resau, B.F. Trump, and C.C. Harris. 1991. Measurement of 4-aminobiphenyl-hemoglobin adducts in lung cancer cases and controls. Cancer Res. 51, 5219-5223.

Talaska, M. Schamer, P.L. Skipper, S.R. Tannenbaum, N. Caporaso, L. Unruh, F.F. Kadlubar, H. Bartsch, C. Malaveille, and P. Vineis. 1991. Detection of carcinogen-DNA adducts in exfoliated urothelial cells of cigarette smokers: associated with smoking, hemoglobin adducts, and urinary mutagenicity. Cancer Epidemiol. and Biomarkers 1, 61-66.

M.S. Bryant, P.L. Skipper, J.S. Wishnok, W.G. Stillwell, J.A. Glogowski, Jr. and S.R. Tannenbaum. 1992. Determination of hemoglobin adducts of aromatic amines by gas chro­matography-mass spectrometry. In: Environmental Carcinogens, Methods of Analysis and Exposure Measurement. IARC Scientific Publications No. 109, International Agency for Research on Cancer: Lyon, France, pp. 275-285.

B.W. Day, M.M. Doxtader, R.H. Rich, P.L. Skipper, K. Singh, R.R. Dasari, and S.R. Tannenbaum. 1992. Human serum albumin-benzo[a]pyrene anti-diol epoxide adduct structure elucidation by fluorescence line narrowing spectroscopy. Chem. Res. Toxicol. 5, 71-76.

T. Nguyen, D. Brunson, C.L. Crespi, B.W. Penman, J.S. Wishnok, and S.R. Tannenbaum. 1992. DNA damage and mutation in human cells exposed to nitric oxide in vitro. Proc. Natl. Acad. Sci. 89, 3030-3034.

S.R. Tannenbaum and J.S. Wishnok. 1992. Genotoxicity of nitric oxide via nitrosative deamina­tion of bases in DNA. IN: Biology of Nitric Oxide. Portland Press, Ltd., pp. 206-208.

Y. Sahali, H. Kwon, P.L. Skipper, and S.R. Tannenbaum. 1992. Microsomal metabolism of cy­clopenta[cd]pyrene. Characterization of new metabolites and their mechanism of formation. Chem. Res. Toxicol. 5, 157-162.

J.D. Groopman, P.L. Skipper, P.R. Donahue, L.J. Trudel, M. Wildschutte, F.F. Kadlubar and S.R. Tannenbaum. 1992. Monoclonal antibodies and rabbit antisera recognizing 4-amino­biphenyl-DNA adducts and application to immunoaffinity chromatography. Carcinogenesis 13, 917-922.

H. Kwon, Y. Sahali, P.L. Skipper, S.R. Tannenbaum. 1992. Oxidation of cyclopenta[cd]pyrene by human and mouse liver microsomes and selected P450 isozymes. Chem. Res. Toxicol. 5, 760-764.

B.W. Day, Y. Sahali, D.A. Hutchins, M. Wildschutte, R. Pastorelli, T.T. Nguyen, S. Naylor, P.L. Skipper, J.S. Wishnok, and S.R. Tannenbaum. 1992. Fluoranthene metabolism: human and rat liver microsomes display different stereoselective formation of the trans-2,3,-dihydrodiol. Chem. Res. Toxicol. 5, 779-786.

N.K. Brown, T.T. Nguyen, K. Taghizadeh, J.S. Wishnok, and S.R. Tannenbaum. 1992. Mutagenic decomposition products of nitrosated 4-chloroindole. Chem. Res. Toxicol. 5, 797-801.

S.R. Tannenbaum, P.L. Skipper, J.S. Wishnok, W.G. Stillwell, B.W. Day, and K. Taghizadeh. 1993. Characterization of various classes of protein adducts. Environ. Health Perspectives 99, 51-55.

J.S. Wishnok, S.R. Tannenbaum, W.G. Stillwell, J.G. Glogowski, and C.D. Leaf. 1993. Urinary markers for exposures to alkylating or nitrosating agents. Environ. Health Perspectives 99, 155-159.

L. Castillo, T.C. de Rojas, T.E. Chapman, J. Vogt, S.R. Tannenbaum, and V.R. Young. 1993. Splanchnic metabolism of dietary arginine in relation to nitric oxide synthesis in normal adult man. Proc. Natl. Acad. Sci. 90, 193-197.

S.K. Hammond, J. Coghlin, P.H. Gann, M. Paul, K. Taghizadeh, P.L. Skipper, and S.R. Tannenbaum. 1993. The relationship between exposure to environmental tobacco smoke and carcinogen-hemogolbin adduct levels in nonsmokers. J. Natl. Canc. Inst. 85, 474-478.

R.S. Lewis, W.M. Deen, S.R. Tannenbaum, and J.S. Wishnok. 1993. Membrane mass spectrom­eter inlet for quantitation of nitric oxide. J. Biol. Mass Spectrometry 22, 45-52.

Y.-J. Surh, H. Kwon, and S.R. Tannenbaum. 1993. Sulfotranfersase-mediated activation of 4-hydroxy- and 3,4-dihydroxy-3,4-dihydrocyclopenta[c,d]pyrene, major metabolites of cy­clopenta[cd]pyrene. Cancer Res. 53, 1017-1022.

S.R. Tannenbaum, S. Tamir, T. deRojas-Walker, and J.S. Wishnok. 1994. DNA damage and cy­totoxicity by nitric oxide. IN: ACS Symposium Series 553, Nitrosamines and Related N-Nitroso Compounds: Chemistry and Biochemistry, Washington, DC. R.A. Loeppky and C.J. Michejda, eds. pp. 120-135.

K. Singh, P.L. Skipper, S.R. Tannenbaum, and R.R. Dasari. 1993. Fluorescence line narrowing studies of antibody-benzo(a)pyrene tetrol complexes. Photochem. and Photobiol. 58, 632-642.

T. Nunoshiba, T. deRojas-Walker, J.S. Wishnok, S.R. Tannenbaum, and B. Demple. 1993. Activation by nitric oxide of an oxidative stress response that defends Escherichia coli against ac­tivated macrophages. Proc. Natl. Acad. Sci. 90, 9993-9997.

S.R. Tannenbaum and P.L. Skipper. 1994. Quantitative analysis of hemoglobin-xenobiotic adducts. In: Methods in Enzymology - Hemoglobins, Chp. XXX - Xenobiotic Adducts of Human Hemoglobin. J. Everse, et al., eds. Academic Press, pp. 625-632.

G.A. Gross, R.J. Turesky, L.B. Fay, W.G. Stillwell, P.L. Skipper, and S.R. Tannenbaum. 1993. Heterocyclic aromatic amine formation in grilled bacon, beef, and fish in grill scrapings. Carcinogenesis 14, 2313-2318.

S. Tamir, R.S. Lewis, T.C. deRojas-Walker, W.M. Deen, J.S. Wishnok, and S.R. Tannenbaum. 1993. The influence of dose rate on the chemistry and biological effects of nitric oxide. Chem. Res. Toxicol. 6, 895-899.

H. Esumi and S.R. Tannenbaum. 1993. U.S.-Japan Cooperative Cancer Research Program: Seminar on "Nitric Oxide Synthase and Carcinogenesis," January 19 and 20, 1993. Cancer Res. 54, 297-301.

R.J. Turesky, W.G. Stillwell, P.L. Skipper, and S.R. Tannenbaum. 1993. Metabolism of the food-borne carcinogens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimi­dazo[4,5-f]quinoxaline (MeIQx) in the rat as a model for human biomonitoring. Environ. Health Perspectives 99, 123-128.

J.G. Fox, J.S. Wishnok, S.R. Tannenbaum, and P. Correa. 1993. MNNG-induced gastric carci­noma in ferrets infected with Helicobacter mustelae. Carcinogenesis 14, 1957-1961.

M.C. Yu, P.L. Skipper, K. Taghizadeh, S.R. Tannenbaum, K.K. Chan, B.E. Henderson, and R.K. Ross. 1994. Acetylator phenotype, aminobiphenyl hemoglobin adduct levels and bladder cancer risk in white, black and asian men in Los Angeles. J. Natl. Cancer Inst. 86, 712-716.

P. Vineis, H. Bartsch, N. Caporaso, A.M. Harrington, F. Kadlubar, M.T. Landi, C. Malaveille, P. Shields, P.L. Skipper, G. Talaska, and S.R. Tannenbaum. 1994. Genetically-based N-acetyltrans­ferase metabolic polymorphisms and low-level environmental exposure to carcinogens. Nature 369, 154-156.

C.K. Soohoo, K. Singh, P.L. Skipper, R.R. Dasari and S.R. Tannenbaum. 1994. Characterization of benzo[a]pyrene anti-diol epoxide adducts to human histones. Chem. Res. Toxicol. 7, 134-138.

P.L. Skipper, X. Peng, C.K. SooHoo, and S.R. Tannenbaum. 1994. Protein adducts as biomarkers of human carcinogen exposure. Drug Metabolism Rev. 26, 111-124.

Y.-J. Surh, and S.R. Tannenbaum. 1994. Bioactivation of cyclopenta- and cyclohexafused polycyclic aromatic hydrocarbons via the formation of benzylic sulfuric acid esters. IN: Polycyclic Aromatic Compounds, Vol. 7, E. Cavalieri, et al., eds., pp. 83-90.

Y.-J. Surh and S.R. Tannenbaum. 1994. Activation of the Maillard reaction product, 5-hydroxymethylfurfural to strong mutagens via allylic sulfonation and chlorination. Chem. Res. Toxicol. 7, 313-318.

W.G. Stillwell, R.J. Turesky, G.A. Gross, P.L. Skipper and S.R. Tannenbaum. 1994. Human urinary excretion of sulfamate and glucuronide conjugates of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). Cancer Epidemiol., Biomarkers & Prev. 3, 399-405.

H. Ji, M.C. Yu, W.G. Stillwell, P.L. Skipper, R.K. Ross, B.E. Henderson, and S.R. Tannenbaum. 1994. Urinary excretion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in white, black, and asian men in Los Angeles Country. Cancer Epidemiol., Biomarkers & Prev. 3, 407-411.

Y. Sahali, P.L. Skipper, and S. Tannenbaum. 1994. Metabolism of Benz[a]anthracene by human liver microsomes. Cancer Lett. 83, 299-303.

Y.-J. Surh, A. Liem, J. Miller, and S.R. Tannenbaum. 1994. 5-Sulfooxymethylfurfural as a possible ultimate mutagenic and carcinogenic metabolite of the Maillard reaction product 5-hydroxymethylfurfural. Carcinogenesis 15, 2375-2377.

C.C. Özbal, I. Velic, C.K. SooHoo, P.L. Skipper, and S.R. Tannenbaum. 1994. Conservation of histone carcinogen adducts during replication: implications for long term molecular dosimetry. Cancer Res. 54, 5599-5601.

B.W. Day, P.L. Skipper, J. Zaia, K. Singh, and S.R. Tannenbaum. 1994. Enantiospecificity of covalent addict formation by benzo[a]pyrene anti-diol epoxide with human serum albumin. Chem. Res. Toxicol. 7, 829-835.

E.A. Carter, T.C. deRojas-Walker, S. Tamir, S.R.Tannenbaum, Y.-M. Yu, and R.G. Tompkins. 1994. Nitric oxide production is intensely and persistently increased in tissues by thermal injury. J. Biochem. 304, 201-204.

P.L. Skipper and S.R. Tannenbaum. 1994. Molecular dosimetry of aromatic amines in human populations. Environ. Health Perspectives 102 (Suppl. 6), 17-21.

R.J. Turesky, G.A. Gross, W.G. Stillwell, P.L. Skipper, and S.R. Tannenbaum. 1994. Species dif­ferences in metabolism of heterocyclic aromatic amines, human exposure and biomonitoring. Environ. Health Perspectives 102 (Suppl. 6), 47-51.

L. Castillo, M. Sanchez, J. Vogt, T.E. Chapman, T.C. deRojas-Walker, S.R. Tannenbaum, A.M. Ajami, and V.R. Young. 1995. Plasma arginine, citrulline, and ornithine kinetics in adults, with observations on nitric oxide synthesis. Am. J. Phys. 268 (Endocrinol. Metab. 31): E360-E367.

S.R. Tannenbaum, S. Stillwell, H. Ji, P. Skipper, M. Yu, R. Ross, B. Henderson, R.J. Turesky, and G.A. Gross. 1995. MeIQx (2-amino-dimethylimidazo[4,5-f]quinoxaline): Metabolism in hu­mans and urinary metabolites in human populations. IN: Heterocyclic Amines in Cooked Foods: Possible Human Carcinogens. Proc. of the International Symposium of the Princess Takamatsu Cancer Research Fund (R.H. Adamson, et al., eds.), Princeton Scientific Publishing Co., Inc., Princeton, NJ, pp. 197-206.

T.C. deRojas-Walker, S. Tamir, H. Ji, J.S. Wishnok, and S.R. Tannenbaum. 1995. Nitric oxide induces oxidative damage in addition to deamination in macrophage DNA. Chem. Res. Toxicol. 8, 473-477.

T. Nunoshiba, T. deRojas-Walker, S.R. Tannenbaum, and B. Demple. 1995. Roles of nitric oxide in inducible resistance of Escherichia coli to activated murine macrophages. Infect. Immun. 63, 794-798.

S.R. Tannenbaum and J.S. Wishnok. 1995. Genotoxicity of nitric oxide via nitrosative deamination of bases in DNA. IN: Biology of Nitric Oxide. (S. Moncada, M.A. Marletta, J.B. Hibbs, Jr. and E.A. Higgs, Editors), Portland Press, Ltd., pp. 206-208.

Y. Surh and S.R. Tannenbaum. 1995. Sulfotransferase-mediated activation of 7,8,9,10-tetrahydro-7-ol, 7,8-dihydrodiol, and 7,8,9,10-tetraol derivatives of benzo[a]pyrene. Chem. Res. Toxicol. 8, 693-698.

S. Tamir, T. deRojas-Walker, A. Gal, A.H. Weller, X. Li, J.G. Fox, G.N. Wogan, and S.R. Tannenbaum. 1995. Nitric oxide production in relation to spontaneous B-cell lymphoma and myositis in SJL mice. Cancer Res. 55, 4391-4397.

B.A.G. Jönsson, J.S. Wishnok, P.L. Skipper, W.G. Stillwell, and S.R. Tannenbaum. 1995. Lysine adducts between methyltetrahydrophthalic anhydride and collagen in guinea pig lung. Toxicol. Appl. Pharmacol. 135, 156-162.

M.C. Yu, R.K. Ross, K.K. Chan, B.E. Henderson, P.L. Skipper, S.R. Tannenbaum, G.A. Coetzee. 1995. Glutathione S-transferase M1 genotype affects aminobiphenyl-hemglobin adduct levels in white, black, and Asian smokers and nonsmokers. Cancer Epidemiol. Biomarkers & Prev. 4, 861-864.

H. Wallin, P.L. Skipper, S.R. Tannenbaum, J.P.A. Jensen, L. Rylander, and J.H. Olsen. 1995. Altered aromatic amine metabolism in epileptic patients treated with phenobarbital. Cancer Epidemiol. Biomarkers & Prev. 4, 771-773.

M.M. Kurrek, L. Castillo, K.D. Block, S.R. Tannenbaum, and W.M. Zapol. 1995. Inhaled nitric oxide does not alter enotoxin-induced nitric oxide synthase activity during rat lung perfusion. J. Physiol. 79, 1088-1092.

R.S. Lewis, S. Tamir, S.R. Tannenbaum, and W.M. Deen. 1995. Kinetic analysis of the fate of nitric oxide synthesized by macrophages in vivo. J. Biol. Chem. 270, 29350-29355.

R.S. Lewis, S.R. Tannenbaum, and W.M. Deen. 1995. Kinetics of N-nitrosation in oxygenated nitric oxide solutions at physiological pH: role of nitrous anhydride and effects of phosphate and chloride. J. Am. Chem. Soc. 117, 3933-3939.

S. Tamir, S. Burney, and S.R. Tannenbaum. 1996. DNA damage by nitric oxide. Chem. Res. Toxicol. 9 (5), 821-827

C.D. Leaf and S.R. Tannenbaum. 1996. The role of dietary nitrate and nitrite in human cancer. IN: Nutrition and Cancer Prevention, R.R. Watson, ed., CRC Press, Chapter 17, 317-324.

J. S. Wishnok, J.A. Glogowski, and S.R. Tannenbaum. 1996. Quantitation of nitrate, nitrite, and nitrosating agents. IN: Nitric Oxide, Lester Packer (editor), Methods in Enzymology Series, Vol. 268, Academic Press, Inc., pp. 130-141.

S. Tamir, T. deRojas-Walker, J.S. Wishnok, and S.R. Tannenbaum. 1996. DNA damage and genotoxicity by nitric oxide. IN: Nitric Oxide, Lester Packer (editor), Methods in Enzymology Series, Vol. 269, Academic Press, Inc., pp. 230-243.

S.R. Tannenbaum. 1995. Safety evaluation of inhaled nitric oxide. IN: Lung Biology in Health and Disease, Marcel Dekker, Inc., New York, pp. 247-250.

S. Luperchio, S. Tamir, and S.R. Tannenbaum. 1996. NO-Induced oxidative stress and glutathione metabolism in rodent and human cells. Free Radical Biol. Med. 21: 513-519.

S. Tamir and S. R. Tannenbaum. 1996. The role of nitric oxide (NO.) in the carcinogenic process. Biochim Biophys Acta 1288, F31-F36.

M.T. Landi, C. Zocchetti, H. Bernucci, F.F. Kadlubar, S. Tannenbaum, P. Skipper, H. Bartsch, C. Malaveille, P. Shields, N.E. Caporaso and P. Vineis. 1996. Cytochrome P4501A2: Enzyme induction and genetic control in determining 4-aminobiphenyl-hemoglobin adduct levels. Cancer Epidemiology, Biomarkers & Prevention, 5, 693-698.

J.L. Caulfield, S.P. Singh, J.S. Wishnok, W.M. Deen, and S.R. Tannenbaum. 1996. Bicarbonate inhibits N-nitrosation in oxygenated nitric oxide solutions. J. Biol. Chem. 271, 25859-25863.

A. Gal, S. Tamir, S.R. Tannenbaum and G.N. Wogan. 1996. Nitric oxide production in SJL mice bearing the RcsX lymphoma: A model for in vivo toxicological evaluation of NO·. Proc. Natl. Acad. Sci. U.S.A., 93, 11499-11503.

M. Keshive, S. Singh, J.S. Wishnok, S.R. Tannenbaum, and W.M. Deen. 1996. Kinetics of nitrosothiol formation. Chem. Res. Toxicol., 9, 988-993.

S.P. Singh, J.S. Wishnok, M. Keshive, W.M. Deen and S.R. Tannenbaum. 1996. The Chemistry of S-Nitrosoglutathione. Proc. Natl. Acad. Sci., 93, 14428-14433.

L.J. Kennedy, K. Moore, Jr., J.L. Caulfield, S.R. Tannenbaum and P.C. Dedon. 1997. Quantitation of 8-oxoguanine and strand breaks produced by four oxidizing agents. Chem. Res. Toxicol., 10, 386-392.

A. Gal, S. Tamir, L.J. Kennedy, S.R. Tannenbaum and G.N. Wogan. 1997. Nitrotyrosine formation, apoptosis, and oxidative damage: Relationships to nitric oxide production in SJL mice bearing the RcsX tumor. Cancer Res., 57, 1823-1828.

V.B. Kartha, R.R. Dasari, C.C. Özbal, P.L. Skipper, and S.r. Tannenbaum. 1997. Subfemtomole detection of PAH adducts of DNA and histones by laser induced fluorescnece. IN: A.P. Roy (ed.), Spectroscopy: Perspectives and Frontiers, pp. 271-283, New Delhi: Narosa Publishing House.

S.P. Harriman, M.J. Hill, S.R. Tannenbaum, and J.S. Wishnok. 1997. Detection and identification of carcinogen-peptide adducts by nanoelectrospray tandem mass spectrometry. J. Am. Soc. Mass Spectrom., 9, 202-207.

C.-H. Hsu, P.L. Skipper, T.M. Harris and S.R. Tannenbaum. 1997. Characterization of DNA adducts formed by Cyclopenta[cd]pyrene epoxide. Chem. Res. Toxicol. 10, 248-253.

S. Burney, S. Tamir, A. Gal and S.R. Tannenbaum. 1997. A mechanistic analysis of nitric oxide-induced cellular toxicity. Nitric Oxide: Biology and Chemistry, 1, 130-144 .

W.G. Stillwell, L.R. Kidd, J.S. Wishnok, S.R. Tannenbaum and R. Sinha. 1997. Urinary excretion of unmetabolized and Phase II conjugates of PhIP and MeIQx in humans: Relationship to cytochrome P4501A2 and NAT2 activity. Cancer Res., 57, 3457-3464.

P. Brunmark, S. Harriman, P.L. Skipper, J.S. Wishnok, S. Amin and S.R Tannenbaum. 1997.
Identification of Subdomain IB in Human Serum Albumin as a Major Binding Site for Polycyclic Aromatic Hydrocarbon Epoxides. Chem. Res. Toxicol. 10, 880-886.

B.J. Hughey, R.E. Klinkowstein, R.E. Shefer, P.L. Skipper, S.R. Tannenbaum, and J.S. Wishnok. 1997. Design of a compact 1 MV AMS system for biomedical research. Nuclear Inst. Meth. Phys. Res., B, 123, 153-158.

N.M. Probst-Hensch, S.R. Tannenbaum, K.K. Chan, G.A. Coetzee, R.K. Ross, and M.C. Yu. 1998. Absence of the glutathione S-transferase M1 gene increases cytochrome P4501A2 activity among frequent consumers of cruciferous vegetables in a Caucasian population. Cancer Epidemiology, Biomarkers & Prevention. 7, 635-638.

S.P. Harriman, J.A. Hill, S.R. Tannenbaum, and J.S. Wishnok. 1998. Detection and identification of carcinogen-peptide adducts by nanoelectrospray tandem mass spectrometry. JASMS, 9, 202-207.

B.J. Hughey, R.E.Klinkowstein, R.E. Shefer, N.A. Fried, P.L. Skipper, J.S. Wishnok, K. Jiao, and S.R. Tannenbaum. 1998. Development of a GC-AMS system for biomedical research. IN: Synthesis and Applications of Isotopically Labelled Compounds 1997. (J.H. Heys and D.G. Melillo, eds.), John Wiley & Sons Ltd., pp. 107-109.

J.L. Caulfield, J.S. Wishnok, and S.R. Tannenbaum. 1998. Nitric oxide-induced deamination of cytosine and guanine in deoxynucleosides and oligonucleotides. J. Biol. Chem. 273 (21), 12689-12695
J. Nair, A. Gal, S. Tamir, S.R. Tannenbaum, G. N. Wogan and H. Bartsch. 1998. Etheno adducts in spleen DNA of SJL mice stimulated to overproduce nitric oxide. Carcinogenesis, 19 (12), 2081-2084.

S. Burney, J.L. Caulfield, J.C. Niles, J.S.Wishnok and S.R. Tannenbaum. 1999. The chemistry of DNA damage from nitric oxide and peroxynitrite. Mutation Resesearch 424, 37-49

C-H. Hsu, P.L. Skipper, and S.R. Tannenbaum. 1999. DNA adduct formation by secondary metabolites of cyclopenta[cd]pyrene in vitro. Cancer Letters 136, 137-141

S. Burney, J.C. Niles, P.C. Dedon, and S.R. Tannenbaum. 1999. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite. Chemical Research In Toxicology 12, 513-520

J.C. Niles, S. Burney, S.P. Singh, J.S. Wishnok and S.R. Tannenbaum. 1999. Peroxynitrite reaction products of 3',5'-di-O-acetyl-7,8-dihydro-8-oxo-2'-deoxyguanosine. Proceedings of the National Academy of Sciences. 96, 11729-11734.

W.G. Stillwell, R.J. Turesky, R. Sinha, P.L. Skipper, and S.R. Tannenbaum. 1999. Biomonitoring of heterocyclic aromatic amine metabolites in human urine. Cancer Lett., 143: 145-148.

N.Y. Tretyakova, J.C. Niles, S. Burney, J.S. Wishnok, and S.R. Tannenbaum. 1999. Peroxynitrite-induced reactions of synthetic oligonucleotides containing 8-oxoguanine. Chem. Res. Toxicol. 12, 459-466.

L.R. Kidd, W.G. Stillwell, M.C. Yu, J.S. Wishnok, P.L. Skipper, R.K. Ross, B.E. Henderson, and S.R. Tannenbaum. 1999. Urinary excretion of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in White, African-American and Asian-American men in Los Angeles County. Cancer Epidemiology, Biomarkers & Prevention, 8, 439-445.

W.G. Stillwell, R.J. Turesky, R.Sinha, and S.R. Tannenbaum. 1999. N-Oxidative metabolism of MeIQx (2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline) in humans: excretion of the N2-glucuronide conjugate of 2-hydroxyamiono-MeIQx in urine. Cancer Res., 59: 5154-5159.

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