Adam H Marblestone

Email: adam.h.marblestone [at] gmail

Publications: google scholar

Patents: google patents



Architecting Discovery: A Model for How Engineers Can Help Invent Tools for Neuroscience (NEURON)

"Sometimes there is a tension in biomedicine: do we pursue basic science for curiosity’s sake, or do we focus on translational work... One way to connect the two is to consider a third path: what if we could accelerate our understanding of the basic science, via new technology, so that we could reduce the risk of translational work, and magnify the impact of the latter?"

How to Study the Brain (The Chronicle Review)

"We can’t simply ask 'what does this bundle of neurons do'? We have to ask, how might the brain work in principle, what clues can we gather from psychology and behavior... To a theoretical physicist, theory might look like elegant mathematical equations that quantitatively predict the behavior of a system. To a computer scientist, theory might mean the construction of classes of algorithms that behave in ways similar to how the brain processes information. Cognitive scientists have theories of the brain that are formulated in other ways..."

Designing Tools for Assumption-Proof Brain Mapping (NEURON)

"The timing is right to elucidate design principles for neuro-technologies that work backward from the fundamental properties of the brain and are equal to the challenge of mapping their mechanisms, rather than working forward from known technology building blocks..."

Selected Talks / Lectures

Fiber optic reflectometry neural recording (Glasgow, 2017): slides

Designing scalable biological interfaces (Harvard, 2014): slides

Stanford cs379c discussion: dense labeling with combinatorial codes (Stanford, 2015): slides, course notes

digital encoding for scalable brain mapping (MIT Media Lab, 2014): slides, video, meeting

Stanford cs379c discussion: molecular ticker tapes (Google, 2013): slides, audio, course notes

billion year old information technologies (TEDxBeaconStreet, 2012): video, TEDx blog, follow-up post

programming matter (Harvard, 2012): video

from quantum noise to heat (Yale, 2008): PDF

quantum entanglement, bell's theorem and reality in 12 minutes (Yale, 2006): PDF

Other talks and lectures I found interesting:

Some of the many papers that have influenced me over the years and/or that just blow my mind:

A few of many technical and semi-technical books that have influenced me over the years:

Some other interesting stuff online:

  • Michael Nielsen on bitcoin
  • Michael Nielsen on the Google technology stack
  • Michael Nielsen on augmenting long-term memory and How can we develop transformative tools for thought?
  • Richard Ngo blog
  • Baez on climate
  • Y Combinator on carbon scrubbing
  • Nintil blog and Longevity talk and Podcast
  • Low cost DNA production roadmap
  • Church lab projects
  • MIT Xapiens club
  • Molecule of the month
  • Astronomy picture of the day
  • Computational psychiatry course readings
  • Guzey on how life sciences actually work
  • Alan Kay on how to fund research
  • Fourmilab
  • Greg Egan, e.g., his story Crystal Nights about developing AGI
  • The lifecycle of software objects: about one way AGI may be developed
  • Hyman on the stalled revolution in neuropsych drug development
  • The Mandelbrot set
  • Aaronson blog
  • Sustainable energy without the hot air
  • SpaceX
  • Graham essays
  • Marginal Revolution University economics courses
  • DNA and Molecular Computation
  • Protocol labs
  • Wolfram
  • NAS on negative emissions
  • ARPA-E ROOTS program
  • Minsky on education (and see OLPC-2 and so on)
  • Minsky in general
  • Merkle
  • The Threshold of Nanotechnology
  • WorryDream's refs
  • Meditations on Moloch
  • Bayesian psychiatry
  • KITP lectures
  • Chapman on: how to evaluate AI progress and alt-research
  • How to become a GOOD theoretical physicist
  • Shalizi notebooks
  • Some posts from gwern that are smart
  • Brain inspired podcast
  • The four layers of intellectual conversation and Reducing unnecessary negativity
  • Paul Christiano
  • BRAIN initiative
  • Sarah Constantin
  • A software agent illustrating some features of an illusionist account of consciousness
  • Cognitive consilience
  • Sinclair predictions on aging
  • Norvig and Lisp in Python
  • Surprised by brains
  • Calico pubs
  • Wait But Why
  • How to Start a Startup
  • Fab Academy
  • Culturing mammalian cells with only plant-based ingredients?
  • Laura Deming Longevity FAQ
  • Weyl Srinivasan podcast
  • Old Edge Master Class on Synthetic Biology by Church and Venter
  • The Long Now Foundation
  • Open Philanthropy Project
  • The Hertz Foundation
  • Bellingcat
  • Multiagent models of mind
  • Biosecurity and biorisk reading list
  • Noahpinion interviews Patrick Collison
  • Moore's law for everything (Sam Altman)
  • The Knowledge (book) and Survivor Library
  • Cummings blog
  • Geothermal Entrepreneurship Organization
  • Steven J Byrnes science programming
  • NeuroMatch academy materials